(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
Acute toxicity- Product Name
- (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
- CAS No.
- 64285-06-9
- Chemical Name
- (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
- Synonyms
- Antx-a;anatoxini;Anatoxin 1;Brn 5477454;(1r)-ethanon;(-)-Anatoxin;(+)-Anatoxin-a;(+/-)-ANATOXIN A;(+/-)-ANATOXIN A FUMERATE;(+/-)-ANATOXIN A FUMARATE
- CBNumber
- CB5154476
- Molecular Formula
- C10H15NO
- Formula Weight
- 165.23
- MOL File
- 64285-06-9.mol
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Property
- alpha
- D25 +39.8°
- Boiling point:
- 293.09°C (rough estimate)
- Density
- 1.0203 (rough estimate)
- refractive index
- 1.5200 (estimate)
- storage temp.
- Desiccate at +4°C
- pka
- 9.4(at 25℃)
- form
- White solid.
- color
- Oil
- EPA Substance Registry System
- Ethanone, 1-(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl- (64285-06-9)
Safety
- Hazardous Substances Data
- 64285-06-9(Hazardous Substances Data)
- Toxicity
- LD50 i.p. in mice: 200 mg/kg (Carmichael)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- TOX0000576
- Product name
- (+/-)-ANATOXIN A
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.04
- Updated
- 2021/12/16
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Chemical Properties,Usage,Production
Acute toxicity
Intraperitoneal-mouse LDL0: 0.25 mg/kg
Occurrence
An oily alkaloid, anatoxin-a has been isolated from Anabaena jfos-aquae.
Uses
(+)-Anatoxin-a is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.
Synthesis Reference(s)
Journal of the American Chemical Society, 106, p. 4539, 1984 DOI: 10.1021/ja00328a040
Biological Activity
A potent nicotinic agonist (K i values are 1.25 and 1840 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Stimulates [ 3 H]-dopamine release from rat striatal synaptosomes (EC 50 = 136 nM).
Safety Profile
Poison by intraperitoneal route.An experimental teratogen. When heated todecomposition it emits toxic fumes of NOx.
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Preparation Products And Raw materials
Raw materials
Preparation Products
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