(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE

Acute toxicity

Product Name: (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
CAS No.: 64285-06-9
Chemical Name: (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
Synonyms: Antx-a;anatoxini;Anatoxin 1;Brn 5477454;(1r)-ethanon;(-)-Anatoxin;(+)-Anatoxin-a;(+/-)-ANATOXIN A;(+/-)-ANATOXIN A FUMERATE;(+/-)-ANATOXIN A FUMARATE
CBNumber: CB5154476
Molecular Formula: C10H15NO
Formula Weight: 165.23
MOL File: 64285-06-9.mol

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(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Property

alpha: D25 +39.8°
Boiling point:: 293.09°C (rough estimate)
Density: 1.0203 (rough estimate)
refractive index: 1.5200 (estimate)
storage temp.: Desiccate at +4°C
pka: 9.4(at 25℃)
form: White solid.
color: Oil
EPA Substance Registry System: Ethanone, 1-(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl- (64285-06-9)

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Safety

Hazardous Substances Data: 64285-06-9(Hazardous Substances Data)
Toxicity: LD50 i.p. in mice: 200 mg/kg (Carmichael)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: TOX0000576
Product name: (+/-)-ANATOXIN A
Purity: 95.00%
Packaging: 5MG
Price: $505.04
Updated: 2021/12/16

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(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Chemical Properties,Usage,Production

Acute toxicity

Intraperitoneal-mouse LDL0: 0.25 mg/kg

Occurrence

An oily alkaloid, anatoxin-a has been isolated from Anabaena jfos-aquae.

Uses

(+)-Anatoxin-a is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.

Synthesis Reference(s)

Journal of the American Chemical Society, 106, p. 4539, 1984 DOI: 10.1021/ja00328a040

Biological Activity

A potent nicotinic agonist (K i values are 1.25 and 1840 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Stimulates [ 3 H]-dopamine release from rat striatal synaptosomes (EC 50 = 136 nM).

Safety Profile

Poison by intraperitoneal route.An experimental teratogen. When heated todecomposition it emits toxic fumes of NOx.

(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Suppliers

Canada 1 CHINA 24 Germany 2 India 1 Japan 1 Norway 1 United Kingdom 5 United States 9 Global 44

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64285-06-9, (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATERelated Search:

Herba Houttuyniae Polysaccharide (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE (+)-ANATOXIN A HYDROCHLORIDE Nodular toxin MICROCYSTIN-LR

(1r)-ethanon

anatoxini

(+/-)-ANATOXIN A

(+/-)-ANATOXIN A FUMARATE

(+/-)-ANATOXIN A FUMERATE

(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE

(-)-Anatoxin

(1β,6β)-5-Acetyl-9-azabicyclo[4.2.1]non-4-ene

[1S,6S,(-)]-2-Acetyl-9-azabicyclo[4.2.1]non-2-ene

(1R,6R)-2-Acetyl-9-azabicyclo[4.2.1]non-2-ene

Anatoxin 1

Antx-a

Brn 5477454

Ethanone, 1-(1R,6R)-9-azabicyclo(4.2.1)non-2-en-2-yl-

Ethanone, 1-(9-azabicyclo(4.2.1)non-2-en-2-yl)-, (1R)-

(+)-Anatoxin-a

(+)-Anatoxin A DISCONTINUED. Please see A653360.

Anatoxin-a (ATX-a) 30 μmol/L in Methanol/Water (9:91) with 0.01% acetic acid

64285-06-9

C10H15NOC4H4O4

Amines

Intermediates & Fine Chemicals

Pharmaceuticals

Nicotinic

Acetylcholine receptor