ChemicalBook > CAS DataBase List > 5-(trifluoromethyl)thiazol-2-amine

5-(trifluoromethyl)thiazol-2-amine

Product Name
5-(trifluoromethyl)thiazol-2-amine
CAS No.
169260-97-3
Chemical Name
5-(trifluoromethyl)thiazol-2-amine
Synonyms
2-aMino-5-trifluoroMethyl-thiazole;5-(trifluoromethyl)thiazol-2-amine;5-(trifluoromethyl)-2-Thiazolamine;5-Trifluoromethyl-thiazol-2-ylamine;2-Thiazolamine, 5-(trifluoromethyl)-;2-Amino-5-trifluoromethyl-1,3-thiazole;5-(trifluoromethyl)-1,3-thiazol-2-amine
CBNumber
CB51559801
Molecular Formula
C4H3F3N2S
Formula Weight
168.14
MOL File
169260-97-3.mol
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5-(trifluoromethyl)thiazol-2-amine Property

Boiling point:
214.0±35.0 °C(Predicted)
Density 
1.557±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
2.61±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

RIDADR 
UN3077
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-WAA0094
Product name
5-(Trifluoromethyl)thiazol-2-amine
Packaging
100mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-WAA0094
Product name
5-(Trifluoromethyl)thiazol-2-amine
Packaging
250mg
Price
$103
Updated
2021/12/16
Ark Pharm
Product number
P000201535
Product name
5-(Trifluoromethyl)thiazol-2-amine
Purity
95+%
Packaging
250mg
Price
$103
Updated
2021/12/16
Ark Pharm
Product number
P000201535
Product name
5-(Trifluoromethyl)thiazol-2-amine
Purity
95+%
Packaging
1g
Price
$307
Updated
2021/12/16
ChemScene
Product number
CS-WAA0094
Product name
5-(Trifluoromethyl)thiazol-2-amine
Packaging
1g
Price
$310
Updated
2021/12/16
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5-(trifluoromethyl)thiazol-2-amine Chemical Properties,Usage,Production

Uses

5-(trifluoromethyl)thiazol-2-amine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Sodium dithionite (1.0 mmol) was added in one portion to a mixture of 2-aminothiazole (1.0 mmol), NaHCO3 (1.0 mmol) and polyfluoroalkyl iodide (1.5 mmol) in acetonitrile/water (4:1/v:v) at 5-10 °C under Ar atmosphere. The mixture was stirred until complete conversion of starting material as indicated by TLC analysis. Acetonitrile was removed under reduced pressure and water (5 mL) was added. The mixture was extracted with ethyl acetate (4.0 mL .x. 3) and the combined organic layers were dried over Na2SO4. The solvent was removed under vacuum and the residue was purified by column chromatography on silica gel (petroleum/ethyl acetate) to give the product.

References

[1] Journal of Fluorine Chemistry, 2012, vol. 133, p. 115 - 119

5-(trifluoromethyl)thiazol-2-amine Preparation Products And Raw materials

Raw materials

Sulfur tetrafluoride Hydrogen fluoride 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID Sodium carbonate

Preparation Products

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View Lastest Price from 5-(trifluoromethyl)thiazol-2-amine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5-(Trifluoromethyl)-1,3-thiazol-2-amine 169260-97-3
Price
US $1.60-9.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-20
Longyan Tianhua Biological Technology Co., Ltd
Product
2-amino-5-trifluoromethyl-thiazole 169260-97-3
Price
US $12.00/Kg/Bag
Min. Order
25Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-11-13
Career Henan Chemical Co
Product
5-(trifluoromethyl)thiazol-2-amine 169260-97-3
Price
US $5.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

169260-97-3, 5-(trifluoromethyl)thiazol-2-amineRelated Search:


  • 5-(trifluoromethyl)thiazol-2-amine
  • 2-aMino-5-trifluoroMethyl-thiazole
  • 5-Trifluoromethyl-thiazol-2-ylamine
  • 5-(trifluoromethyl)-2-Thiazolamine
  • 2-Amino-5-trifluoromethyl-1,3-thiazole
  • 5-(trifluoromethyl)-1,3-thiazol-2-amine
  • 2-Thiazolamine, 5-(trifluoromethyl)-
  • 169260-97-3