2-AMINOTHIAZOLE-5-CARBOXYLIC ACID

Product Name: 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID
CAS No.: 40283-46-3
Chemical Name: 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID
Synonyms: RARECHEM AL BE 1263;2-Amino-5-carboxy-1,3-thiazole;2-Aminothizole-5-carboxylic acid;Heterocyclic coMpounds / Pyrazole;2-AMINOTHIAZOLE-5-CARBOXYLIC ACID;2-AMINO-5-THIAZOLECARBOXYLIC ACID;2-AMINOTHIAZOL-5-YLCARBOXYLIC ACID;5-Thiazolecarboxylic acid, 2-aMino-;2-Amino-1,3-thiazole-5-carboxylic acid;2-Aminothiazole-5-carboxylic acid, >=98%
CBNumber: CB9116986
Molecular Formula: C4H4N2O2S
Formula Weight: 144.15
MOL File: 40283-46-3.mol

More

Less

2-AMINOTHIAZOLE-5-CARBOXYLIC ACID Property

Melting point:: 214-216
Boiling point:: 415.0±18.0 °C(Predicted)
Density: 1.657±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 2.14±0.10(Predicted)
form: Crystalline Powder
color: Off-white to yellow

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
Hazard Note: Irritant/Keep Cold
HS Code: 29341000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: A615650
Product name: 2-Aminothiazole-5-carboxylicAcid
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA36283
Product name: 2-Aminothiazole-5-carboxylic acid
Packaging: 5G
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 069813
Product name: 2-Aminothiazole-5-carboxylic acid
Purity: 98%
Packaging: 25g
Price: $98
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA36283
Product name: 2-Aminothiazole-5-carboxylic acid
Packaging: 10g
Price: $110
Updated: 2021/12/16

Apolloscientific

Product number: OR9398
Product name: 2-Amino-1,3-thiazole-5-carboxylicacid
Purity: 95%
Packaging: 1g
Price: $10
Updated: 2021/12/16

More

Less

2-AMINOTHIAZOLE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

32955-21-8

40283-46-3

General procedure for the synthesis of 2-aminothiazole-5-carboxylic acid from ethyl 2-aminothiazole-5-carboxylate: sodium hydroxide (0.65 g, 16.3 mmol) was added to a mixed THF/water (2:1, v/v) solution containing ethyl 2-aminothiazole-5-carboxylate (0.80 g, 4.32 mmol) and the reaction mixture was heated to reflux overnight. Upon completion of the reaction, THF was removed by distillation under reduced pressure.Subsequently, the reaction mixture was neutralized with 1 M hydrochloric acid solution. The resulting precipitate was collected by filtration, washed with ether and dried at 60 °C overnight. An off-white crystalline product was obtained in 86% yield with a melting point of 168-171 °C (literature value: 172-173 °C). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.81 (s, 1H, thiazole-H), 8.99 (br s, 2H, NH2) ppm. high-resolution mass spectrometry (HRMS-ESI) analysis: m/z [M+H]+ calculated value of 145.1475 (C4H5N2O2S), measured value 145.1502.

References

[1] European Journal of Medicinal Chemistry, 2013, vol. 67, p. 208 - 220
[2] Recueil des Travaux Chimiques des Pays-Bas, 1944, vol. 63, p. 226
[3] Yakugaku Zasshi, 1948, vol. 68, p. 101
[4] Chem.Abstr., 1953, p. 7452
[5] Chemische Berichte, 1943, vol. 76, p. 419,428

2-AMINOTHIAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

5-(trifluoromethyl)thiazol-2-amine

More

Less

2-AMINOTHIAZOLE-5-CARBOXYLIC ACID Suppliers

Belgium 1 China 116 Germany 4 India 9 Japan 1 Switzerland 1 United Kingdom 4 United States 24 Global 160

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

More

Less

View Lastest Price from 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID 40283-46-3
Price: US $150.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20KG
Release date: 2018-07-27

40283-46-3, 2-AMINOTHIAZOLE-5-CARBOXYLIC ACIDRelated Search:

Ethyl 2-amino-4-methylthiazole-5-carboxylate Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate ETHYL 2-(TERT-BUTOXYCARBONYLAMINO)THIAZOLE-5-CARBOXYLATE 2-AMINOTHIAZOLE-4-CARBOXYLIC ACID 95%,2-Aminothiazole-4-carboxylic acid,2-AMINOTHIAZOLE-4-CARBOXYLIC ACID HYDROBROMIDE 2-BOC-AMINOTHIAZOLE-4-CARBOXYLIC ACID Ethyl 2-aminothiazole-4-carboxylate hydrochloride Methyl 2-Aminothiazole-4-carboxylate 2-AMINOTHIAZOLE-4-CARBOXYLIC ACID, ETHYL ESTERHYDROCHLORIDE Ethyl 2-aminothiazole-5-carboxylate 2-AMINOTHIAZOLE-4-CARBOXYLIC ACID HYDROBROMIDE Methyl 2-aminothiazole-5-carboxylate 4-AMINO-3-PHENYL-2-THIOXO-2,3-DIHYDRO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 2-N-BOC-AMINO-THIAZOLE-5-CARBOXYLIC ACID 2-Aminothiazole-5-carboxylic acid amide 2-Aminothiazole Thiazole-5-carboxylic acid 2-AMINO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER 2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C&

2-AMINO-5-THIAZOLECARBOXYLIC ACID

2-AMINOTHIAZOLE-5-CARBOXYLIC ACID

2-AMINOTHIAZOL-5-YLCARBOXYLIC ACID

RARECHEM AL BE 1263

2-Amino-1,3-thiazole-5-carboxylic acid

2-Amino-1,3-thiazole-5-carboxylic acid 98%

2-Amino-5-carboxy-1,3-thiazole

5-Thiazolecarboxylic acid, 2-aMino-

Heterocyclic coMpounds / Pyrazole

2-Aminothiazole-5-carboxylic acid, >=98%

2-Aminothizole-5-carboxylic acid

40283-46-3

Amines

blocks

Carboxes

Thiazoles