BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID
- Product Name
- BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID
- CAS No.
- 83673-98-7
- Chemical Name
- BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID
- Synonyms
- N-BOC protected;2-Boc-AminothiazoL;3-thiazole-4-carboxylic acid;2-BOC-AMINOTHIAZOLE-4-CARBOXYLIC ACID;BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID;BOC-2-AMINO-4-THIAZOLE-CARBIXYLIC ACID;N-Boc-2-aMino thiazole-4-carboxylic acid;2-(N-BOC-Amino)-thiazol-4-carboxylic acid;2-(tert-butoxycarbonyl)thiazole-4-carboxylic acid;2-TERT-BUTOXYCARBONYLAMINOTHIAZOLE-4-CARBOXYLIC ACID
- CBNumber
- CB7314193
- Molecular Formula
- C9H12N2O4S
- Formula Weight
- 244.27
- MOL File
- 83673-98-7.mol
BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID Property
- Melting point:
- 250-252
- Density
- 1.406±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 5.53±0.70(Predicted)
- form
- solid
- color
- Pale yellow
- InChI
- InChI=1S/C9H12N2O4S/c1-9(2,3)15-8(14)11-7-10-5(4-16-7)6(12)13/h4H,1-3H3,(H,12,13)(H,10,11,14)
- InChIKey
- PIWSRJPUYPNQJE-UHFFFAOYSA-N
- SMILES
- S1C=C(C(O)=O)N=C1NC(OC(C)(C)C)=O
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-43
- Safety Statements
- 26-36/37/39-36/37
- HazardClass
- IRRITANT
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B6144
- Product name
- 2-[(tert-Butoxycarbonyl)amino]thiazole-4-carboxylic Acid
- Packaging
- 1G
- Price
- $42
- Updated
- 2025/07/31
- Product number
- B6144
- Product name
- 2-[(tert-Butoxycarbonyl)amino]thiazole-4-carboxylic Acid
- Packaging
- 5G
- Price
- $167
- Updated
- 2025/07/31
- Product number
- B619673
- Product name
- 2-Boc-Aminothiazole-4-carboxylicAcid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B619673
- Product name
- 2-Boc-Aminothiazole-4-carboxylicAcid
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B619673
- Product name
- 2-Boc-Aminothiazole-4-carboxylicAcid
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
189512-01-4
83673-98-7
GENERAL METHOD: An aqueous KOH solution (10% w/v) was added to a THF solution containing ethyl 2-((tert-butoxycarbonyl)amino)thiazole-4-carboxylate. The reaction mixture was stirred at room temperature until the complete disappearance of the ingredients was confirmed by thin layer chromatography (TLC). Subsequently, the pH was adjusted to 4 by adding 1 M HCl and the reaction solution was extracted with ethyl acetate (EtOAc). The organic layer was dried with anhydrous magnesium sulfate (MgSO4) and subsequently concentrated under reduced pressure to afford the target product 2-Boc-aminothiazole-4-carboxylic acid.
References
[1] European Journal of Medicinal Chemistry, 2017, vol. 126, p. 776 - 788
[2] Patent: US2006/41146, 2006, A1. Location in patent: Page/Page column 15
[3] Journal of the American Chemical Society, 2000, vol. 122, # 27, p. 6382 - 6394
[4] Chinese Chemical Letters, 2015, vol. 26, # 10, p. 1315 - 1318
[5] Patent: US2002/173490, 2002, A1
BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BOC-2-AMINO-4-THIAZOLE-CARBOXYLIC ACID manufacturers
- Product
- 2-BOC-aminothiazole-4-carboxylic acid 83673-98-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-10
- Product
- 2-BOC-aminothiazole-4-carboxylic acid 83673-98-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-09