2-Aminothiazole
- Product Name
- 2-Aminothiazole
- CAS No.
- 96-50-4
- Chemical Name
- 2-Aminothiazole
- Synonyms
- Aminothiazole;1,3-Thiazol-2-amine;aminothiazol;2-THIAZOLAMINE;Abadol;cp1585;BASEDOL;RP 2921;ABADOLE;AKOS 204-05
- CBNumber
- CB5215834
- Molecular Formula
- C3H4N2S
- Formula Weight
- 100.14
- MOL File
- 96-50-4.mol
2-Aminothiazole Property
- Melting point:
- 91-93 °C (lit.)
- Boiling point:
- 117 °C (15.002 mmHg)
- Density
- 1.241 (estimate)
- vapor pressure
- <1 hPa (20 °C)
- refractive index
- 1.5300 (estimate)
- Flash point:
- 117°C/15mm
- storage temp.
- Store below +30°C.
- solubility
- 1 M HCl: soluble50mg/mL, clear (dark yellow-brown)
- pka
- 5.36(at 20℃)
- form
- Crystalline Powder, Grains, Lumps or Flakes
- color
- Brown
- PH
- 9.6 (100g/l, H2O, 20℃)
- Water Solubility
- 100 g/L (20 ºC)
- Merck
- 14,479
- BRN
- 105738
- InChIKey
- RAIPHJJURHTUIC-UHFFFAOYSA-N
- LogP
- 0.380
- CAS DataBase Reference
- 96-50-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Aminothiazole(96-50-4)
- EPA Substance Registry System
- 2-Aminothiazole (96-50-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36-36/37-20/21/22
- Safety Statements
- 26-36/37-39-36
- WGK Germany
- 3
- RTECS
- XJ2100000
- F
- 8-9
- Autoignition Temperature
- 600 °C
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29341000
- Toxicity
- LD50 orally in Rabbit: 480 mg/kg
N-Bromosuccinimide Price
- Product number
- 8.01272
- Product name
- 2-Aminothiazole
- Purity
- for synthesis
- Packaging
- 100g
- Price
- $41.9
- Updated
- 2024/03/01
- Product number
- 123129
- Product name
- 2-Aminothiazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $30.1
- Updated
- 2024/03/01
- Product number
- 8.01272
- Product name
- 2-Aminothiazole
- Purity
- for synthesis
- Packaging
- 500g
- Price
- $152
- Updated
- 2024/03/01
- Product number
- 123129
- Product name
- 2-Aminothiazole
- Purity
- 97%
- Packaging
- 100g
- Price
- $57.1
- Updated
- 2024/03/01
- Product number
- A0633
- Product name
- 2-Aminothiazole
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $22
- Updated
- 2024/03/01
2-Aminothiazole Chemical Properties,Usage,Production
Chemical Properties
brown crystalline powder, grains, lumps or flakes
Uses
antithyroid agent
Uses
Usually used in the synthesis of 2-aminothiazole-modified silica gel，and aslo used in Ulmann coupling with 2-chlorobenzoic acids mediated by ultrasonic irradiation.
Uses
2-Aminothiazole is a heterocyclic amine and is the beginning reagent for the synthesis of many pharmaceutical and agricultural related compounds.
Definition
ChEBI: A primary amino compound that is 1,3-thiazole substituted by an amino group at position 2.
Synthesis Reference(s)
Journal of the American Chemical Society, 76, p. 693, 1954 DOI: 10.1021/ja01632a016
General Description
Light brown crystals or brown granular solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Aminothiazole reacts violently when nitrated with nitric or nitric-sulfuric acids. 2-Aminothiazole is also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides.
Fire Hazard
Flash point data for 2-Aminothiazole are not available; however, 2-Aminothiazole is probably combustible.
Biochem/physiol Actions
2-Aminothiazoles are potent cyclin-dependent kinase 5 inhibitors and are therapeutic agents for the treatment of Alzheimer′s disease and other neurodegenerative disorders.
Safety Profile
Poison by ingestion andintraperitoneal routes. Mutation data reported.Spontaneous ignition occurs at 100°. Mixtures with nitricacid or nitric acid + sulfuric acid explode on heating.Incompatible with HNO3 and H2SO4. When heated todecomposition it emi
Purification Methods
It crystallises from pet ether (b 100-120o), or EtOH. [Beilstein 27 III/IV 4574.]
2-Aminothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Aminothiazole manufacturers
- Product
- 2-Aminothiazole 96-50-4
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 200mt/year
- Release date
- 2021-07-08
- Product
- 2-Aminothiazole 96-50-4
- Price
- US $58.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-22
- Product
- 2-Aminothiazole 96-50-4
- Price
- US $75.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10T
- Release date
- 2021-06-03