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2-Amino-5-nitrothiazole

Uses
Product Name
2-Amino-5-nitrothiazole
CAS No.
121-66-4
Chemical Name
2-Amino-5-nitrothiazole
Synonyms
5-Nitrothiazol-2-amine;ENHEPTYNE;Nitazoxanide Related Compound A (25 mg) (2-Amino-5-nitrothiazole);NSC 4;ENHEPTIN;entramin;AKOS 203;ENTRAMINE;enheptint;nci-c03065
CBNumber
CB5143401
Molecular Formula
C3H3N3O2S
Formula Weight
145.14
MOL File
121-66-4.mol
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2-Amino-5-nitrothiazole Property

Melting point:
195-200 °C (dec.) (lit.)
Boiling point:
345.1±15.0 °C(Predicted)
Density 
1.583 (estimate)
refractive index 
1.6740 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
95% ethanol: soluble1g/150g at 20°C
form 
Powder
pka
1.26±0.10(Predicted)
color 
Yellow
Water Solubility 
<0.1 g/100 mL at 20 ºC
Sensitive 
Light Sensitive
Merck 
14,457
BRN 
126797
Stability:
Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.
InChIKey
MIHADVKEHAFNPG-UHFFFAOYSA-N
CAS DataBase Reference
121-66-4(CAS DataBase Reference)
IARC
3 (Vol. 31, Sup 7) 1987
EPA Substance Registry System
2-Amino-5-nitrothiazole (121-66-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
XJ2800000
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29341000
Hazardous Substances Data
121-66-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2889
Product name
Nitazoxanide Related Compound A
Purity
pharmaceutical secondary standard, certified reference material
Packaging
50MG
Price
$518
Updated
2024/03/01
Sigma-Aldrich
Product number
133507
Product name
2-Amino-5-nitrothiazole
Purity
97%
Packaging
25g
Price
$43.6
Updated
2024/03/01
Sigma-Aldrich
Product number
133507
Product name
2-Amino-5-nitrothiazole
Purity
97%
Packaging
100g
Price
$62
Updated
2024/03/01
TCI Chemical
Product number
A0381
Product name
2-Amino-5-nitrothiazole
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
A0381
Product name
2-Amino-5-nitrothiazole
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$993
Updated
2023/06/20
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2-Amino-5-nitrothiazole Chemical Properties,Usage,Production

Uses

Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole.

Chemical Properties

greenish yellow, to orange or brown powder

Uses

2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein.

Definition

ChEBI: 2-Amino-5-nitrothiazole is a member of thiazoles and a C-nitro compound.

Production Methods

Early production of 2-Amino-5-nitrothiazole was based on nitration of 2-acetylaminothiazole and careful hydrolysis. Direct nitration of 2-aminothiazole gives a cleaner product and is best achieved by adding 2-aminothiazole nitrate [57530-25-3] to concentrated sulfuric acid at 0 – 10 ℃. This process and the nitration of o-anisidine are the only large-scale processes based on rearrangement of an amine nitrate, and both are potentially hazardous due to the possibility of runaway exothermic reactions.

General Description

Greenish-yellow to orange-yellow fluffy powder or a brown chunky powder. Slightly bitter taste. Used as a veterinary medicine.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Amino-5-nitrothiazole may be sensitive to light. Incompatible with nitric acid and sulfuric acid. Also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. A preparative hazard .

Fire Hazard

Flash point data for 2-Amino-5-nitrothiazole are not available. 2-Amino-5-nitrothiazole is probably combustible.

Safety Profile

Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SO,. Incompatible with HNO3 and H2SO4. An antiprotozoal agent.

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2-Amino-5-nitrothiazole Suppliers

Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd.
Tel
+86-512-58813106 15862625988
Fax
0512-58813106
Email
sales@clentchem.com
Country
China
ProdList
165
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60
Shijiazhuang Outejia Chemical Co. LTD
Tel
0311-87795622
Fax
0311-87709298
Email
sales@adonghui.com
Country
China
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Hebei mo Jin biotechnology co., ltd
Tel
15097329902
Fax
18503279000
Email
sales@hebeimojin.com
Country
China
ProdList
2253
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58
Hubei Jiuchang New Material Technology Co., Ltd
Tel
13407109540
Email
15216757546@163.com
Country
China
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136
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58
Ningbo Meisheng Jiahe Pharmaceutical Technology Co., LTD
Tel
17855810803
Email
msjhpharm@163.com
Country
China
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26
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58
Shandong Wanhe Chemical Technology Co., Ltd
Tel
18854132367
Email
sales@wanhechemical.com
Country
China
ProdList
120
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Shanghai Lankun Pharmaceutical Technology Co., Ltd
Tel
18616122638 18616122638
Email
saleslee@kunrising.com
Country
China
ProdList
52
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
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View Lastest Price from 2-Amino-5-nitrothiazole manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Enheptyne;2-Amino-5-nitrothiazole 121-66-4
Price
US $10.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
1000tons/month
Release date
2024-03-21
Shandong Juchuang Chemical Co., LTD
Product
2-Amino-5-nitrothiazole 121-66-4
Price
US $44.00-22.00/kg
Min. Order
500kg
Purity
99.9
Supply Ability
200tons
Release date
2024-03-13
Shaanxi Dideu Medichem Co. Ltd
Product
2-Amino-5-nitrothiazole 121-66-4
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-26

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