2-Amino-5-nitrothiazole
Uses- Product Name
- 2-Amino-5-nitrothiazole
- CAS No.
- 121-66-4
- Chemical Name
- 2-Amino-5-nitrothiazole
- Synonyms
- 5-Nitrothiazol-2-amine;ENHEPTYNE;Nitazoxanide Related Compound A (25 mg) (2-Amino-5-nitrothiazole);NSC 4;ENHEPTIN;entramin;AKOS 203;ENTRAMINE;enheptint;nci-c03065
- CBNumber
- CB5143401
- Molecular Formula
- C3H3N3O2S
- Formula Weight
- 145.14
- MOL File
- 121-66-4.mol
2-Amino-5-nitrothiazole Property
- Melting point:
- 195-200 °C (dec.) (lit.)
- Boiling point:
- 345.1±15.0 °C(Predicted)
- Density
- 1.583 (estimate)
- refractive index
- 1.6740 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- 95% ethanol: soluble1g/150g at 20°C
- form
- Powder
- pka
- 1.26±0.10(Predicted)
- color
- Yellow
- Water Solubility
- <0.1 g/100 mL at 20 ºC
- Sensitive
- Light Sensitive
- Merck
- 14,457
- BRN
- 126797
- Stability:
- Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.
- InChIKey
- MIHADVKEHAFNPG-UHFFFAOYSA-N
- CAS DataBase Reference
- 121-66-4(CAS DataBase Reference)
- IARC
- 3 (Vol. 31, Sup 7) 1987
- EPA Substance Registry System
- 2-Amino-5-nitrothiazole (121-66-4)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- XJ2800000
- F
- 8
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29341000
- Hazardous Substances Data
- 121-66-4(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHR2889
- Product name
- Nitazoxanide Related Compound A
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 50MG
- Price
- $518
- Updated
- 2024/03/01
- Product number
- 133507
- Product name
- 2-Amino-5-nitrothiazole
- Purity
- 97%
- Packaging
- 25g
- Price
- $43.6
- Updated
- 2024/03/01
- Product number
- 133507
- Product name
- 2-Amino-5-nitrothiazole
- Purity
- 97%
- Packaging
- 100g
- Price
- $62
- Updated
- 2024/03/01
- Product number
- A0381
- Product name
- 2-Amino-5-nitrothiazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- A0381
- Product name
- 2-Amino-5-nitrothiazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 500g
- Price
- $993
- Updated
- 2023/06/20
2-Amino-5-nitrothiazole Chemical Properties,Usage,Production
Uses
Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole.
Chemical Properties
greenish yellow, to orange or brown powder
Uses
2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein.
Definition
ChEBI: 2-Amino-5-nitrothiazole is a member of thiazoles and a C-nitro compound.
Production Methods
Early production of 2-Amino-5-nitrothiazole was based on nitration of 2-acetylaminothiazole and careful hydrolysis. Direct nitration of 2-aminothiazole gives a cleaner product and is best achieved by adding 2-aminothiazole nitrate [57530-25-3] to concentrated sulfuric acid at 0 – 10 ℃. This process and the nitration of o-anisidine are the only large-scale processes based on rearrangement of an amine nitrate, and both are potentially hazardous due to the possibility of runaway exothermic reactions.
General Description
Greenish-yellow to orange-yellow fluffy powder or a brown chunky powder. Slightly bitter taste. Used as a veterinary medicine.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Amino-5-nitrothiazole may be sensitive to light. Incompatible with nitric acid and sulfuric acid. Also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. A preparative hazard .
Fire Hazard
Flash point data for 2-Amino-5-nitrothiazole are not available. 2-Amino-5-nitrothiazole is probably combustible.
Safety Profile
Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SO,. Incompatible with HNO3 and H2SO4. An antiprotozoal agent.
Potential Exposure
2-Amino-5-nitrothiazole is a synthetic veterinary antiprotozoal agent used since 1950 to treat farm fowl and pigeons. It is also used as an intermediate in manufacturing a group of dyes known as disperse azo dyes. It is not known to occur as a natural product. People may be exposed to 2-amino-5-nitrothiazole through contact with birds treated with the drug, releases from poultry farms, and occupational exposures in the dye industry.
2-Amino-5-nitrothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-5-nitrothiazole manufacturers
- Product
- 2-Amino-5-nitrothiazole 121-66-4
- Price
- US $350.00/kg
- Min. Order
- 200kg
- Purity
- 99%
- Supply Ability
- 5 tons
- Release date
- 2024-04-24
- Product
- Enheptyne;2-Amino-5-nitrothiazole 121-66-4
- Price
- US $10.00/kg
- Min. Order
- 25kg
- Purity
- 99%
- Supply Ability
- 1000tons/month
- Release date
- 2024-03-21
- Product
- 2-Amino-5-nitrothiazole 121-66-4
- Price
- US $44.00-22.00/kg
- Min. Order
- 500kg
- Purity
- 99.9
- Supply Ability
- 200tons
- Release date
- 2024-03-13