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CARUMONAM

Product Name
CARUMONAM
CAS No.
87638-04-8
Chemical Name
CARUMONAM
Synonyms
AMA 1080;CARUMONAM;Ro 17-2301;CarlliIIonaln;CARUMONAM USP/EP/BP;Ro-17-2301：A-masulin;Antibiotic Ro 17-2301;(2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid;[[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid;[[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
CBNumber
CB5165269
Molecular Formula
C12H14N6O10S2
Formula Weight
466.4
MOL File
87638-04-8.mol
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CARUMONAM Property

alpha 
D26 -45° (c = 1 in DMSO)
Density 
2.13±0.1 g/cm3(Predicted)
pka
-0.43±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0007950
Product name
CARUMONAM
Purity
95.00%
Packaging
5MG
Price
$500.38
Updated
2021/12/16
AHH
Product number
MT-48971
Product name
Carumonam
Purity
98%
Packaging
0.1g
Price
$230
Updated
2021/12/16
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CARUMONAM Chemical Properties,Usage,Production

Description

Canunonam is an injectable antibiotic, the second monobactam ever developed (the first being Squibb’s aztreonam). It is highly active against Gram negative bacteria, particularly pseudomom, and is reportedly effective in the treatment of pneumonia, cystitis, peritonitis and secondary infections.

Originator

Takeda (Japan)

Definition

ChEBI: An N-sulfonated monobactam antibiotic.

brand name

Amasulin

Antimicrobial activity

A synthetic monobactam with activity against common pathogenic organisms similar to that of aztreonam. It is resistant to hydrolysis by the common plasmid and chromosomal β-lactamases, but it can be hydrolyzed by ESBLs.
It is administered intravenously, achieving a concentration of c. 78 mg/L after a 20-min infusion of 1 g. The plasma halflife is 1.7 h and the plasma protein binding 18–28%. Carumonam is almost entirely eliminated in the glomerular filtrate, probenecid having no effect on excretion; 96% of labeled compound is found in the urine, with 3% in the feces. Between 68% and 91% of the dose appears in the urine within 24 h.
Side effects and clinical use are similar to those of aztreonam.

CARUMONAM Preparation Products And Raw materials

Raw materials

Sodium borohydride Benzyl chloroformate 2,3-Di-O-para-toluoyl-D-tartaric acid

Preparation Products

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CARUMONAM Suppliers

China 17 Europe 2 India 1 United Kingdom 3 United States 10 Global 33
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
UK GREEN SCIENTIFIC CO.,LIMITED
Tel
--
Fax
--
Email
sales@gs-chem.com
Country
United Kingdom
ProdList
6098
Advantage
47
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View Lastest Price from CARUMONAM manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
CaruMonaM 87638-04-8
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-07
Career Henan Chemical Co
Product
CARUMONAM 87638-04-8
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

87638-04-8, CARUMONAMRelated Search:

Aztreonam DATMA CEFIXIME CARUMONAM CARUMONAM INTERMEDIATE (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid (S)-2-AZETIDINEMETHANOL Carumonam disodium salt CARUMONAM

  • CARUMONAM
  • Acetic acid, [[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
  • Acetic acid, [[[2-[[2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, [2S-[2α,3α(Z)]]-
  • AMA 1080
  • Antibiotic Ro 17-2301
  • Ro 17-2301
  • (2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid
  • [[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid
  • [[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
  • [2S-[2α，3α(Z)]]-[[[2-[[2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
  • CarlliIIonaln
  • Ro-17-2301：A-masulin
  • Acetic acid, 2-[[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
  • CARUMONAM USP/EP/BP
  • 87638-04-8
  • C12H14N6O10S2