(-)-LEUKOTRIENE A4 METHYL ESTER

Product Name: (-)-LEUKOTRIENE A4 METHYL ESTER
CAS No.: 73466-12-3
Chemical Name: (-)-LEUKOTRIENE A4 METHYL ESTER
Synonyms: (-)-leukotriene A4;PWXYNAKNLZUYAL-WAQVJNLQSA-N;LEUKOTRIENE A4 METHYL ESTER;(-)-LEUKOTRIENE A4 METHYL ESTER;LTA4 (Leukotriene A4 methyl ester);5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER;LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE);2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-
CBNumber: CB5184743
Molecular Formula: C21H32O3
Formula Weight: 332.48
MOL File: 73466-12-3.mol

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(-)-LEUKOTRIENE A4 METHYL ESTER Property

storage temp.: −20°C
solubility: Acetone: >50 mg/ml; DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: insoluble and unstable.
form: triethylamine:hexane solution

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Safety

Hazard Codes: F,Xn,N
Risk Statements: 11-36/37/38-48/20-51/53-62-65-67
Safety Statements: 9-16-29-33-36/37-61-62
RIDADR: UN 1208 3/PG 2
WGK Germany: 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

H315Causes skin irritation

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P331Do NOT induce vomiting.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20010
Product name: Leukotriene A4 methyl ester
Purity: ≥97%
Packaging: 25μg
Price: $144
Updated: 2024/03/01

Cayman Chemical

Product number: 20010
Product name: Leukotriene A4 methyl ester
Purity: ≥97%
Packaging: 50μg
Price: $274
Updated: 2024/03/01

Cayman Chemical

Product number: 20010
Product name: Leukotriene A4 methyl ester
Purity: ≥97%
Packaging: 100μg
Price: $519
Updated: 2024/03/01

Cayman Chemical

Product number: 20010
Product name: Leukotriene A4 methyl ester
Purity: ≥97%
Packaging: 500μg
Price: $1579
Updated: 2023/06/20

TRC

Product number: L473505
Product name: LTA4(LeukotrieneA4methylester)
Packaging: 0.1mg
Price: $290
Updated: 2021/12/16

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(-)-LEUKOTRIENE A4 METHYL ESTER Chemical Properties,Usage,Production

Description

Leukotriene A₄ (LTA₄) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA₄ synthase activities. LTA₄ is rapidly metabolized by LTA₄ hydrolase or LTC₄ synthase to LTB₄ or LTC₄, respectively. LTA₄, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA₄ by 15-LO leads to lipoxin biosynthesis. LTA₄ as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

Uses

LTA4 (Leukotriene A4 methyl ester) is an unstable intermediate in the biosynthesis of LTB4 and LTC4.

(-)-LEUKOTRIENE A4 METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-LEUKOTRIENE A4 METHYL ESTER Suppliers

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73466-12-3, (-)-LEUKOTRIENE A4 METHYL ESTERRelated Search:

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(-)-LEUKOTRIENE A4 METHYL ESTER

LEUKOTRIENE A4 METHYL ESTER

(-)-leukotriene A4

LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE)

LTA4 (Leukotriene A4 methyl ester)

PWXYNAKNLZUYAL-WAQVJNLQSA-N

5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER

2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-

73466-12-3

Biochemicals and Reagents

BioChemical

Unsaturated fatty acids and derivatives

Esters

Fatty Acids

Methyl Esters

Lipids