ChemicalBook > CAS DataBase List > DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE

DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE

Product Name
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
CAS No.
881-95-8
Chemical Name
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
Synonyms
DL-METANEPHRINE HYDROCHLORIDE;METANEPHRINE HYDROCHLORIDE;Methoxyadrenaline;METANEPHRINE (HCL);DL-MetanephrineHCl;Epinephrine Impurity 29;Metadrenaline Hydrochloride;Metanephrine HCl (solution);Metanephrine hydrochloride salt;3-methoxy-adrenalinhydrochloride
CBNumber
CB5185427
Molecular Formula
C10H16ClNO3
Formula Weight
233.69
MOL File
881-95-8.mol
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DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Property

Melting point:
180-182?C
Density 
1.320 g/cm3
storage temp. 
2-8°C
solubility 
H2O: soluble
form 
powder
color 
white to off-white
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
DA4798000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0399
Product name
D,L-Metanephrine hydrochloride
Purity
≥98% (HPLC)
Packaging
10mg
Price
$155
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0399
Product name
D,L-Metanephrine hydrochloride
Purity
≥98% (HPLC)
Packaging
50mg
Price
$613
Updated
2024/03/01
TRC
Product number
M258760
Product name
racMetanephrineHydrochlorideSalt
Packaging
10mg
Price
$110
Updated
2021/12/16
TRC
Product number
M258760
Product name
racMetanephrineHydrochlorideSalt
Packaging
500mg
Price
$1295
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
4167
Product name
Metanephrinehydrochloride
Purity
>99%
Packaging
100mg
Price
$390
Updated
2021/12/16
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DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A metabolite of Epinephrine (E588585). A naturraly occurring derivative of Epinephrine, found in urine and in certain tissues.

Biochem/physiol Actions

Metanephrine is an endogenous metabolite of ephinephrine, formed by catechol-O-methyl transferase activity. It is best known as a biomarker for cancers, as levels of free metanephrine are used to diagnose pheochromocytoma. Metanephrine was previously thought to be biologically inactive, but it is a more potent agonist at Trace amine associated receptor TAAR1 than either epinephrine or norepinephrine. Trace amine associated receptors (TAARs) are recently discovered GPCRs that are activated by endogenous trace amines (tyramine, tryptamine, synephrine, octopamine, β-phenylethylamine), which are chemically similar to monoaminergic neurotransmitters (epinephrine, norepinephrine, dopamine). Trace amines and TAARs are expressed in brain and are implicated in modulation of monoaminergic neurotransmission.

DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE Suppliers

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881-95-8, DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDERelated Search:

Methoxyammonium chloride Norepinephrine L(-)-Epinephrine NOSCAPINE HYDROCHLORIDE Dipivefrin hydrochloride (+)-B-HYDRASTINE HCL DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE BICUCULLINE METHYLCHLORIDE (-), [METHYL-3H] PHOMOPSIN A DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE METANEPHRINE HYDROCHLORIDE [N-METHYL-3H] (-)-BICUCULLINE METHOCHLORIDE BICUCULLINE METHYLCHLORIDE (-), [METHYL-14C] (-)-BICUCULLINE METHCHLORIDE, 1(S),9(R) NOSCAPINE HYDROCHLORIDE HYDRATE TIMTEC-BB SBB006457 LABOTEST-BB LT00847526 SALOR-INT L123331-1EA

  • (+-)-4-hydroxy-3-methoxy-alpha-((methylamino)methyl)benzenemethanolhydrochlo
  • 3-methoxy-adrenalinhydrochloride
  • 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-benzenemethanohydrochlorid
  • alpha-((methylamino)methyl)-vanillylalcohohydrochloride
  • 4-HYDROXY-3-METHOXY-ALPHA-[METHYLAMINOMETHYL]BENZENE-METHANOL HYDROCHLORIDE
  • 4-HYDROXY-3-METHOXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE
  • METANEPHRINE (HCL)
  • METANEPHRINE HYDROCHLORIDE
  • DL-METANEPHRINE HYDROCHLORIDE
  • DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
  • (.+-)-alpha-[(methylamino)methyl]vanillyl alcohol hydrochloride
  • METANEPHRINE HYDROCHLORIDE >97% REFERENC E STD. FOR CH
  • DL-MetanephrineHCl
  • DL-m-O-Methylepinephrine hydrochloride, 4-Hydroxy-3-methoxy-α-(methylaminomethyl)benzene-methanol hydrochloride
  • DL-MetanephrineCl (not deuterated)
  • (+/-)-alpha-[(Methylamino)methyl]vanillyl alcohol hydrochloride
  • (+/-)-Metanephrine hydrochloride
  • 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride
  • 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxy-phenol hydrochloride
  • 4-Hydroxy-3-Methoxy-α-[(MethylaMino)Methyl]benzeneMethanol Hydrochloride
  • Metadrenaline Hydrochloride
  • α-[(MethylaMino)Methyl]-vanillyl Alcohol Hydrochloride
  • DL-3-O-Methyladrenaline hydrochloride
  • m-O-Methyladrenaline hydrochloride
  • D,L-Metanephrine hydrochloride salt
  • Metanephrine HCl (solution)
  • Metanephrine hydrochloride salt
  • rac Metanephrine Hydrochloride Salt (0.1mg/mL in Methanol)
  • Methoxyadrenaline
  • Metanephrine 13C D3 hydrochloride
  • Metanephrine Hydrochloride (Rac)
  • Epinephrine Impurity 29
  • DL-M-O-Methylepinephrine hydrochloride?New
  • Benzenemethanol, 4-hydroxy-3-methoxy-α-[(methylamino)methyl]- , hydrochloride (1:1) (ACI)
  • rac Metanephrine Hydrochloride Salt/Metanephrine HCl
  • (+/-)-Metanephrine hydrochloride in methanol
  • rac Metanephrine Hydrochloride Salt(as free base) in Methanol
  • 881-95-8
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Standards - 13C & 2H for GC-Mass Spectrometry