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NOSCAPINE HYDROCHLORIDE

Product Name
NOSCAPINE HYDROCHLORIDE
CAS No.
912-60-7
Chemical Name
NOSCAPINE HYDROCHLORIDE
Synonyms
NOSCAPINEHCL;opianhydrochloride;capvalhydrochloride;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE / HCL;coscopinhydrochloride;longatinhydrochloride;nectadonhydrochloride
CBNumber
CB4168056
Molecular Formula
C22H24ClNO7
Formula Weight
449.88
MOL File
912-60-7.mol
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NOSCAPINE HYDROCHLORIDE Property

Melting point:
221-223 °C(lit.)
storage temp. 
2-8°C
solubility 
Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand.
form 
neat
color 
Crystals
Merck 
13,6752
EPA Substance Registry System
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22
Safety Statements 
36
RIDADR 
1544
WGK Germany 
3
RTECS 
NP7225000
10
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
cyt-ham:fbr 60 mg/L ESKHA5 96,55,78
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N9007
Product name
Noscapine hydrochloride hydrate
Purity
analytical standard
Packaging
5g
Price
$68.2
Updated
2020/08/18
Sigma-Aldrich
Product number
N9007
Product name
Noscapine hydrochloride hydrate
Purity
analytical standard
Packaging
25g
Price
$269
Updated
2020/08/18
TCI Chemical
Product number
N0963
Product name
Noscapine Hydrochloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$76
Updated
2021/03/22
Cayman Chemical
Product number
17255
Product name
Noscapine (hydrochloride)
Purity
≥98%
Packaging
5g
Price
$174
Updated
2021/03/22
Cayman Chemical
Product number
17255
Product name
Noscapine (hydrochloride)
Purity
≥98%
Packaging
1g
Price
$44
Updated
2021/03/22
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NOSCAPINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, hygroscopic.

Uses

topical fluoroquinolone antibiotic for acne

Uses

Anti-Tussive

Biological Activity

Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion and subcutaneous routes.Mutation data reported. When heated to decomposition itemits very toxic fumes of HCl and NOx.

NOSCAPINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NOSCAPINE HYDROCHLORIDE Suppliers

Qinghai Pharmaceutical Factory Co., Ltd.
Tel
--
Fax
--
Email
xcf@qhzhiyao.com、sqj@qhzhiyao.com
Country
China
ProdList
11
Advantage
58
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14457
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-67601398-809
Fax
021-57711696
Email
marketing_china@spectrumchemical.com;
Country
China
ProdList
9686
Advantage
60
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-3668-0489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28438
Advantage
80
TCI Europe
Tel
320-37350700-
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23696
Advantage
75
TCI AMERICA
Tel
+1-800-423-8616 / +1-503-283-1681
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
United States
ProdList
23679
Advantage
75
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399-
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4575
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810- ;025-57798810-
Fax
025-57019371
Email
sales@sunlidabio.com;sales@sunlidabio.com
Country
China
ProdList
3756
Advantage
55
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View Lastest Price from NOSCAPINE HYDROCHLORIDE manufacturers

Dideu Industries Group Limited
Product
NOSCAPINE HYDROCHLORIDE USP/EP/BP 912-60-7
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100Tons min
Release date
2021-06-10
Longyan Tianhua Biological Technology Co., Ltd
Product
Noscapine Hydrochloride Hydrate 912-60-7
Price
US $200.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2020-11-13
Shaanxi Dideu Medichem Co. Ltd
Product
Noscapine Hydrochloride Hydrate 912-60-7
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-04-24

912-60-7, NOSCAPINE HYDROCHLORIDERelated Search:


  • NOSCAPINE HYDROCHLORIDE
  • NARCOTINE HYDROCHLORIDE
  • ,3-dioxolo(4,5-g)isoquinolin-5-yl)-,hydrochloride,(s-(r*,s*))-
  • 1(3h)isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1
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  • nectadonhydrochloride
  • nsc5366hydrochloride
  • opianhydrochloride
  • opianinehydrochloride
  • terbenolhydrochloride
  • tusscapinehydrochloride
  • vadebexhydrochloride
  • NOSCAPINE EP STANDARD
  • NOSCAPINE USP STANDARD
  • NOSCAPINEHCL
  • (3S)-6,7-DIMETHOXY-3-[(5R)-5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-1(3H)-ISOBENZOFURANONE HYDROCHLORIDE
  • 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]-
  • 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI)
  • l-Narcotine hydrochloride
  • Narcotine, hydrochloride (7CI, 8CI)
  • NOSCAPINE BASE / HCL
  • Noscapine hydrate hydrochloride
  • 6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one hydrochloride
  • (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride
  • Noscapine hydrochloride hydrate,Narcotine hydrochloride
  • Narcotine HCl((S,R)-Noscapine)
  • Noscapine HCl(Nectodon)
  • NoscapineHydrochlorideMonohydrate&gt
  • NOSCAPINE HYDROCHLORIDE USP/EP/BP
  • 912-60-7
  • C22H23NO7ClH
  • C22H23NO7HCl
  • C22H23NO7HClxH2O
  • C23H23NO7HCl
  • Analytical Standards
  • Analytical Chromatography Product Catalog
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  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Complex Molecules
  • NJ - NZ
  • Inhibitors