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NOSCAPINE HYDROCHLORIDE

Product Name
NOSCAPINE HYDROCHLORIDE
CAS No.
912-60-7
Chemical Name
NOSCAPINE HYDROCHLORIDE
Synonyms
capvalhydrochloride;NOSCAPINEHCL;opianhydrochloride;noscapiniumchlorid;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE / HCL;Noscapinhydrochlorid;coscopinhydrochloride
CBNumber
CB4168056
Molecular Formula
C22H24ClNO7
Formula Weight
449.88
MOL File
912-60-7.mol
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NOSCAPINE HYDROCHLORIDE Property

Melting point:
221-223 °C(lit.)
storage temp. 
2-8°C
solubility 
Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand.
color 
Crystals
Merck 
13,6752
EPA Substance Registry System
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22
Safety Statements 
36
RIDADR 
1544
WGK Germany 
3
RTECS 
NP7225000
F 
10
HS Code 
2939.19.5000
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
cyt-ham:fbr 60 mg/L ESKHA5 96,55,78
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H336May cause drowsiness or dizziness

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N9007
Product name
Noscapine hydrochloride hydrate
Purity
analytical standard
Packaging
5g
Price
$91
Updated
2024/03/01
Sigma-Aldrich
Product number
N9007
Product name
Noscapine hydrochloride hydrate
Purity
analytical standard
Packaging
25g
Price
$360
Updated
2024/03/01
TCI Chemical
Product number
N0963
Product name
Noscapine Hydrochloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$108
Updated
2024/03/01
Cayman Chemical
Product number
17255
Product name
Noscapine (hydrochloride)
Purity
≥98%
Packaging
1g
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
17255
Product name
Noscapine (hydrochloride)
Purity
≥98%
Packaging
5g
Price
$213
Updated
2024/03/01
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NOSCAPINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, hygroscopic.

Uses

Anti-Tussive

Uses

Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.

Uses

topical fluoroquinolone antibiotic for acne

Biological Activity

Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion and subcutaneous routes.Mutation data reported. When heated to decomposition itemits very toxic fumes of HCl and NOx.

NOSCAPINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NOSCAPINE HYDROCHLORIDE Suppliers

Americas 1 Belgium 2 China 79 Europe 3 Germany 1 India 22 Iran 3 Japan 1 South Korea 1 Switzerland 3 The Netherlands 1 United Kingdom 6 United States 25 Venezuela 1 Global 149
Qinghai Pharmaceutical Factory Co., Ltd.
Tel
0971-5506700
Fax
NULL
Email
xcf@qhzhiyao.com、sqj@qhzhiyao.com
Country
China
ProdList
9
Advantage
58
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
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View Lastest Price from NOSCAPINE HYDROCHLORIDE manufacturers

Dideu Industries Group Limited
Product
NOSCAPINE HYDROCHLORIDE 912-60-7
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100Tons min
Release date
2021-06-10
Longyan Tianhua Biological Technology Co., Ltd
Product
Noscapine Hydrochloride Hydrate 912-60-7
Price
US $200.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2020-11-13
Shaanxi Dideu Medichem Co. Ltd
Product
Noscapine Hydrochloride Hydrate 912-60-7
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-04-24

912-60-7, NOSCAPINE HYDROCHLORIDERelated Search:

dioxifedrine 3-Methoxysalicylic acid 5-HYDROXYDOPAMINE HYDROCHLORIDE (+)-B-HYDRASTINE HCL Methyl 3-methoxysalicylate 7-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Ethyl 2-hydroxybenzoate NOSCAPINE HYDROCHLORIDE (1S,2R)-2-Amino-1,2-diphenylethanol 2-(1-Aminoethyl)-4-hydroxybenzyl alcohol hydrochloride (S)-1-(2-Methoxyphenyl)ethylamine (S)-7-METHOXY-1-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL 3-[(1S)-1-(Dimethylaminoethyl)]phenol Bis(tert-butyldioxyisopropyl)benzene tert-Butyl 1-benzhydryl-3-azetidinylcarbamate Triadimenol A 1-Pyrrolidinobutyronitrile

  • NOSCAPINE HYDROCHLORIDE
  • NARCOTINE HYDROCHLORIDE
  • ,3-dioxolo(4,5-g)isoquinolin-5-yl)-,hydrochloride,(s-(r*,s*))-
  • 1(3h)isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1
  • 1-alpha-narcotinehydrochloride
  • capvalhydrochloride
  • coscopinhydrochloride
  • coscotabshydrochloride
  • key-tusscapinehydrochloride
  • longatinhydrochloride
  • lyobexhydrochloride
  • methoxyhydrastinehydrochloride
  • narcomprenhydrochloride
  • narcosinehydrochloride
  • nectadonhydrochloride
  • nsc5366hydrochloride
  • opianhydrochloride
  • opianinehydrochloride
  • terbenolhydrochloride
  • tusscapinehydrochloride
  • vadebexhydrochloride
  • NOSCAPINE EP STANDARD
  • NOSCAPINE USP STANDARD
  • NOSCAPINEHCL
  • (3S)-6,7-DIMETHOXY-3-[(5R)-5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-1(3H)-ISOBENZOFURANONE HYDROCHLORIDE
  • 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]-
  • 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI)
  • l-Narcotine hydrochloride
  • Narcotine, hydrochloride (7CI, 8CI)
  • NOSCAPINE BASE / HCL
  • Noscapine hydrate hydrochloride
  • 6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one hydrochloride
  • (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride
  • Noscapine hydrochloride hydrate,Narcotine hydrochloride
  • Narcotine HCl((S,R)-Noscapine)
  • Noscapine HCl(Nectodon)
  • NoscapineHydrochlorideMonohydrate&gt
  • NOSCAPINE HYDROCHLORIDE USP/EP/BP
  • Noscapinhydrochlorid
  • Papaverine hydrochloride impurity A （NACOTINE HYDROCHLORIDE）
  • noscapiniumchlorid
  • 912-60-7
  • C22H23NO7ClH
  • C22H23NO7HCl
  • C22H23NO7HClxH2O
  • C23H23NO7HCl
  • Analytical Standards
  • Analytical Chromatography Product Catalog
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  • Asymmetric Synthesis
  • Complex Molecules
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  • Inhibitors