ChemicalBook > CAS DataBase List > Ethyl 2-hydroxybenzoate

Ethyl 2-hydroxybenzoate

Product Name
Ethyl 2-hydroxybenzoate
CAS No.
118-61-6
Chemical Name
Ethyl 2-hydroxybenzoate
Synonyms
Mesotol;Salotan;salethyl;Sal Ethyl;Ethyl Liu;FEMA 2458;salicylicether;Ethylsalicylat;Salicylic ether;ETHYL SALICYLATE
CBNumber
CB1723193
Molecular Formula
C9H10O3
Formula Weight
166.17
MOL File
118-61-6.mol
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Ethyl 2-hydroxybenzoate Property

Melting point:
1 °C (lit.)
Boiling point:
234 °C (lit.)
Density 
1.131 g/mL at 25 °C (lit.)
vapor pressure 
0.05 mm Hg ( 25 °C)
FEMA 
2458 | ETHYL SALICYLATE
refractive index 
n20/D 1.522(lit.)
Flash point:
225 °F
storage temp. 
Store below +30°C.
solubility 
0.25g/l
pka
9.93±0.10(Predicted)
form 
Liquid
color 
Clear colorless to pale yellow
explosive limit
1.1%(V)
Water Solubility 
slightly soluble
JECFA Number
900
Merck 
14,3850
BRN 
907659
InChIKey
GYCKQBWUSACYIF-UHFFFAOYSA-N
CAS DataBase Reference
118-61-6(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6)
EPA Substance Registry System
Ethyl salicylate (118-61-6)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/38-52/53
Safety Statements 
26-36
WGK Germany 
1
RTECS 
VO3000000
TSCA 
Yes
HS Code 
29182390
Toxicity
LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
112291
Product name
Ethyl salicylate
Purity
99%
Packaging
100g
Price
$23.4
Updated
2021/03/22
Sigma-Aldrich
Product number
112291
Product name
Ethyl salicylate
Purity
99%
Packaging
250g
Price
$30.4
Updated
2021/03/22
Sigma-Aldrich
Product number
8.41018
Product name
Ethyl salicylate
Purity
for synthesis
Packaging
250 mL
Price
$30.8
Updated
2021/03/22
Sigma-Aldrich
Product number
W245801
Product name
Ethyl salicylate
Purity
≥99%, FCC, FG
Packaging
1 kg
Price
$61
Updated
2021/03/22
Sigma-Aldrich
Product number
8.41018
Product name
Ethyl salicylate
Purity
for synthesis
Packaging
1 L
Price
$95.27
Updated
2021/03/22
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Ethyl 2-hydroxybenzoate Chemical Properties,Usage,Production

Description

Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents. 

Chemical Properties

clear colourless to pale yellow liquid

Chemical Properties

Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. It has a pleasant odor resembling winter green and is used in perfumery and artificial flavors.

Chemical Properties

Ethyl salicylate has a characteristic aromatic odor similar to wintergreen. It tends to darken on exposure to light and air.

Occurrence

Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa fruit, papaya and scotch.

Uses

manufacture of artificial perfumes.

Production Methods

Ethyl salicylate is found naturally in currants and strawberries . It is manufactured commercially by the esterification of salicylic acid with ethyl alcohol.

Preparation

By esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.

Taste threshold values

Taste characteristics at 10 ppm: sweet, wintergreen, spicy and anisic.

References

Sheu, Yaw-Wen, and Chein-Hsiun Tu. "Densities and viscosities of binary mixtures of ethyl acetoacetate, ethyl isovalerate, methyl benzoate, benzyl acetate, ethyl salicylate, and benzyl propionate with ethanol at T=(288.15, 298.15, 308.15, and 318.15) K." Journal of Chemical & Engineering Data 51.2 (2006): 545-553.
Filippa, Mauricio, Matías I. Sancho, and Estela Gasull. "Encapsulation of methyl and ethyl salicylates by β-cyclodextrin: HPLC, UV–vis and molecular modeling studies." Journal of pharmaceutical and biomedical analysis 48.3 (2008): 969-973.

Ethyl 2-hydroxybenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 2-hydroxybenzoate Suppliers

Nanjing Jiangyan Chemical Co., Ltd.
Tel
15850530966
Email
13912946682@139.com
Country
China
ProdList
6
Advantage
58
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-2580635- ;0712-2580635
Email
1791901229@qq.com;1791901229@qq.com;
Country
China
ProdList
8939
Advantage
52
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
sales.gd@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
Energy Chemical
Tel
021-58432009-
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
43496
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028-
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12356
Advantage
60
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View Lastest Price from Ethyl 2-hydroxybenzoate manufacturers

Anhui Rencheng Technology Co., Ltd
Product
Ethyl salicylate 118-61-6
Price
US $10.00-180.00/KG
Min. Order
0.5KG
Purity
>99%
Supply Ability
20tons
Release date
2020-12-29
Hebei Crovell Biotech Co Ltd
Product
Ethyl 2-Hydroxybenzoate 118-61-6
Price
US $8.70/Kg/Drum
Min. Order
10g
Purity
99%
Supply Ability
10000kg
Release date
2021-07-09
Dideu Industries Group Limited
Product
Ethyl 2-hydroxybenzoate USP/EP/BP 118-61-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-21

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