ethyl salicylate

Product Name: ethyl salicylate
CAS No.: 118-61-6
Chemical Name: ethyl salicylate
Synonyms: ETHYL SALICYLATE;Mesotol;Ethyl salicyclate;Salotan;salethyl;Sal Ethyl;Ethyl Liu;FEMA 2458;salicylicether;Ethylsalicylat
CBNumber: CB1723193
Molecular Formula: C9H10O3
Formula Weight: 166.17
MOL File: 118-61-6.mol

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ethyl salicylate Property

Melting point:: 1 °C (lit.)
Boiling point:: 234 °C (lit.)
Density: 1.131 g/mL at 25 °C (lit.)
vapor pressure: 0.05 mm Hg ( 25 °C)
refractive index: n20/D 1.522(lit.)
FEMA: 2458 | ETHYL SALICYLATE
Flash point:: 225 °F
storage temp.: Store below +30°C.
solubility: 0.25g/l
form: Liquid
pka: 9.93±0.10(Predicted)
color: Clear colorless to pale yellow
Odor: at 100.00 %. sweet wintergreen mint floral spicy balsam
Odor Type: minty
biological source: synthetic
explosive limit: 1.1%(V)
Water Solubility: slightly soluble
Merck: 14,3850
JECFA Number: 900
BRN: 907659
Dielectric constant: 8.6（21℃）
InChIKey: GYCKQBWUSACYIF-UHFFFAOYSA-N
LogP: 3.07 at 21.9℃
CAS DataBase Reference: 118-61-6(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6)
EPA Substance Registry System: Ethyl salicylate (118-61-6)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/38-52/53
Safety Statements: 26-36
WGK Germany: 1
RTECS: VO3000000
TSCA: Yes
HS Code: 29182390
Toxicity: LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W245801
Product name: Ethyl salicylate
Purity: ≥99%, FCC, FG
Packaging: 1kg
Price: $40.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: W245801
Product name: Ethyl salicylate
Purity: ≥99%, FCC, FG
Packaging: 10Kg
Price: $325
Updated: 2024/03/01

Sigma-Aldrich

Product number: W245801
Product name: Ethyl salicylate
Purity: ≥99%, FCC, FG
Packaging: 25kg
Price: $699
Updated: 2024/03/01

Sigma-Aldrich

Product number: 112291
Product name: Ethyl salicylate
Purity: 99%
Packaging: 100g
Price: $28
Updated: 2024/03/01

Sigma-Aldrich

Product number: 112291
Product name: Ethyl salicylate
Purity: 99%
Packaging: 250g
Price: $55.4
Updated: 2024/03/01

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ethyl salicylate Chemical Properties,Usage,Production

Description

Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents.

Chemical Properties

Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. It has a pleasant odor resembling winter green and is used in perfumery and artificial flavors.

Chemical Properties

Ethyl salicylate has a characteristic aromatic odor similar to wintergreen. It tends to darken on exposure to light and air.

Occurrence

Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa fruit, papaya and scotch.

Uses

Ethyl salicylate is a non-steroidal analgesic, anti-inflammatory and antirrheumatic drug. Its complexation with β-cyclodextrin was studied using reversed-phase liquid chromatography.

Uses

Ethyl salicylate may be used as an analytical standard for the determination of the analyte in biological fluids and topical formulation by chromatography-based techniques.

Definition

ChEBI: Ethyl salicylate is a hydroxybenzoic acid.

Production Methods

Ethyl salicylate is found naturally in currants and strawberries . It is manufactured commercially by the esterification of salicylic acid with ethyl alcohol.

Preparation

Ethyl 2-hydroxybenzoate is prepared by esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.

Taste threshold values

Taste characteristics at 10 ppm: sweet, wintergreen, spicy and anisic.

General Description

Ethyl salicylate was hydrolysed to salicylic acid by the use of an extractive electrospray ionisation (EESI) device.

Flammability and Explosibility

Not classified

References

Sheu, Yaw-Wen, and Chein-Hsiun Tu. "Densities and viscosities of binary mixtures of ethyl acetoacetate, ethyl isovalerate, methyl benzoate, benzyl acetate, ethyl salicylate, and benzyl propionate with ethanol at T=(288.15, 298.15, 308.15, and 318.15) K." Journal of Chemical & Engineering Data 51.2 (2006): 545-553.
Filippa, Mauricio, Matías I. Sancho, and Estela Gasull. "Encapsulation of methyl and ethyl salicylates by β-cyclodextrin: HPLC, UV–vis and molecular modeling studies." Journal of pharmaceutical and biomedical analysis 48.3 (2008): 969-973.

ethyl salicylate Preparation Products And Raw materials

Raw materials

Salicylic acid Ethanol Hydrochloric acid alcohol Ethyl p-toluenesulfonate Aluminum sulfate

Preparation Products

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ethyl salicylate Suppliers

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View Lastest Price from ethyl salicylate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Ethyl 2-Hydroxybenzoate 118-61-6
Price: US $180.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-31

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Ethyl 2-hydroxybenzoate 118-61-6
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-09

Hebei Chuanghai Biotechnology Co., Ltd

Product: Ethyl 2-hydroxybenzoate 118-61-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-01

118-61-6, ethyl salicylateRelated Search:

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118-61-6

102-47-8

2HOC6H4CO2C2H5

HOC6H4COOC2H5

Building Blocks

ACETATE

Carbonyl Compounds

C8 to C9

Esters

Organic Building Blocks

Heterocyclic Compounds

Aromatic Esters

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