NOSCAPINE HYDROCHLORIDE

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NOSCAPINE HYDROCHLORIDE

Product Name: NOSCAPINE HYDROCHLORIDE
CAS No.: 912-60-7
Chemical Name: NOSCAPINE HYDROCHLORIDE
Synonyms: capvalhydrochloride;NOSCAPINEHCL;opianhydrochloride;noscapiniumchlorid;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE / HCL;Noscapinhydrochlorid;coscopinhydrochloride
CBNumber: CB4168056
Molecular Formula: C22H24ClNO7
Formula Weight: 449.88
MOL File: 912-60-7.mol

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NOSCAPINE HYDROCHLORIDE Property

Melting point:: 221-223 °C(lit.)
storage temp.: 2-8°C
solubility: Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand.
color: Crystals
Merck: 13,6752
EPA Substance Registry System: 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22
Safety Statements: 36
RIDADR: 1544
WGK Germany: 3
RTECS: NP7225000
F: 10
HS Code: 2939.19.5000
HazardClass: 6.1(b)
PackingGroup: III
Toxicity: cyt-ham:fbr 60 mg/L ESKHA5 96,55,78

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H336May cause drowsiness or dizziness

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N9007
Product name: Noscapine hydrochloride hydrate
Purity: analytical standard
Packaging: 5g
Price: $91
Updated: 2024/03/01

Sigma-Aldrich

Product number: N9007
Product name: Noscapine hydrochloride hydrate
Purity: analytical standard
Packaging: 25g
Price: $360
Updated: 2024/03/01

TCI Chemical

Product number: N0963
Product name: Noscapine Hydrochloride Hydrate
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $108
Updated: 2024/03/01

Cayman Chemical

Product number: 17255
Product name: Noscapine (hydrochloride)
Purity: ≥98%
Packaging: 1g
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 17255
Product name: Noscapine (hydrochloride)
Purity: ≥98%
Packaging: 5g
Price: $213
Updated: 2024/03/01

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NOSCAPINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, hygroscopic.

Uses

Anti-Tussive

Uses

Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.

Uses

topical fluoroquinolone antibiotic for acne

Biological Activity

Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion and subcutaneous routes.Mutation data reported. When heated to decomposition itemits very toxic fumes of HCl and NOx.

NOSCAPINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NOSCAPINE HYDROCHLORIDE Suppliers

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View Lastest Price from NOSCAPINE HYDROCHLORIDE manufacturers

Dideu Industries Group Limited

Product: NOSCAPINE HYDROCHLORIDE 912-60-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100Tons min
Release date: 2021-06-10

Longyan Tianhua Biological Technology Co., Ltd

Product: Noscapine Hydrochloride Hydrate 912-60-7
Price: US $200.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-11-13

Shaanxi Dideu Medichem Co. Ltd

Product: Noscapine Hydrochloride Hydrate 912-60-7
Price: US $0.01-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50 tons
Release date: 2020-04-24

912-60-7, NOSCAPINE HYDROCHLORIDERelated Search:

dioxifedrine 3-Methoxysalicylic acid 5-HYDROXYDOPAMINE HYDROCHLORIDE (+)-B-HYDRASTINE HCL Methyl 3-methoxysalicylate 7-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Ethyl 2-hydroxybenzoate NOSCAPINE HYDROCHLORIDE (1S,2R)-2-Amino-1,2-diphenylethanol 2-(1-Aminoethyl)-4-hydroxybenzyl alcohol hydrochloride (S)-1-(2-Methoxyphenyl)ethylamine (S)-7-METHOXY-1-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL 3-[(1S)-1-(Dimethylaminoethyl)]phenol Bis(tert-butyldioxyisopropyl)benzene tert-Butyl 1-benzhydryl-3-azetidinylcarbamate Triadimenol A 1-Pyrrolidinobutyronitrile

NOSCAPINE HYDROCHLORIDE

NARCOTINE HYDROCHLORIDE

,3-dioxolo(4,5-g)isoquinolin-5-yl)-,hydrochloride,(s-(r*,s*))-

1(3h)isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1

1-alpha-narcotinehydrochloride

capvalhydrochloride

coscopinhydrochloride

coscotabshydrochloride

key-tusscapinehydrochloride

longatinhydrochloride

lyobexhydrochloride

methoxyhydrastinehydrochloride

narcomprenhydrochloride

narcosinehydrochloride

nectadonhydrochloride

nsc5366hydrochloride

opianhydrochloride

opianinehydrochloride

terbenolhydrochloride

tusscapinehydrochloride

vadebexhydrochloride

NOSCAPINE EP STANDARD

NOSCAPINE USP STANDARD

NOSCAPINEHCL

(3S)-6,7-DIMETHOXY-3-[(5R)-5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-1(3H)-ISOBENZOFURANONE HYDROCHLORIDE

1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]-

1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI)

l-Narcotine hydrochloride

Narcotine, hydrochloride (7CI, 8CI)

NOSCAPINE BASE / HCL

Noscapine hydrate hydrochloride

6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one hydrochloride

(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride

Noscapine hydrochloride hydrate,Narcotine hydrochloride

Narcotine HCl((S,R)-Noscapine)

Noscapine HCl(Nectodon)

NoscapineHydrochlorideMonohydrate&gt

NOSCAPINE HYDROCHLORIDE USP/EP/BP

Noscapinhydrochlorid

Papaverine hydrochloride impurity A （NACOTINE HYDROCHLORIDE）

noscapiniumchlorid

912-60-7

C22H23NO7ClH

C22H23NO7HCl

C22H23NO7HClxH2O

C23H23NO7HCl

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