ChemicalBook > CAS DataBase List > 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester

1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester

Uses

Product Name: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester
CAS No.: 808137-94-2
Chemical Name: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester
Synonyms: SW-99;SWF-99;Methyl 7-;Methyl 7-azaindole-3-carb...;Methyl 7-azaindole-3-carboxylate;Methyl 7-azaindole-3-carboxylate 97%;Methyl 1H-pyrrolo[2,3-b]pyridine-3-carbo×ylate;Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate;1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester;Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate, 3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine
CBNumber: CB51872067
Molecular Formula: C9H8N2O2
Formula Weight: 176.17
MOL File: 808137-94-2.mol

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1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Property

Melting point:: 57-59℃
Density: 1.324
storage temp.: Sealed in dry,Room Temperature
pka: 12.30±0.40(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C9H8N2O2/c1-13-9(12)7-5-11-8-6(7)3-2-4-10-8/h2-5H,1H3,(H,10,11)
InChIKey: XYRUNIAHPKBUJT-UHFFFAOYSA-N
SMILES: C12NC=C(C(OC)=O)C1=CC=CN=2

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Safety

HS Code: 2933992000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: M321415
Product name: Methyl1H-Pyrrolo[2,3-b]pyridine-3-carboxylate
Packaging: 500mg
Price: $90
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H23-1-M5
Product name: Methyl 7-azaindole-3-carboxylate
Packaging: 1g
Price: $99
Updated: 2021/12/16

ChemScene

Product number: CS-B0498
Product name: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,methylester
Packaging: 5g
Price: $124
Updated: 2021/12/16

AK Scientific

Product number: J51157
Product name: Methyl1H-pyrrolo[2,3-b]pyridine-3-carboxylate
Packaging: 5g
Price: $183
Updated: 2021/12/16

ChemScene

Product number: CS-B0498
Product name: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,methylester
Packaging: 10g
Price: $245
Updated: 2021/12/16

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1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Chemical Properties,Usage,Production

Uses

1H-pyrrolo[2,3-B]pyridine-3-carboxylic acid methyl ester is a carboxylic acid ester derivative that can be used as an organic synthesis intermediate and has a wide range of applications in the fields of medicine, food, pesticides, and daily chemicals.

Synthesis

4414-89-5

808137-94-2

(3) In a reaction flask, 100 mL of methanol and 100 mL of hydrochloric acid (10 mol/L) were added, and 28.6 g of 3-cyano-7-azaindole (0.2 mol) was dissolved in the mixed solvent, and the reaction was stirred for 10 hours at 80°C. The reaction was carried out at 80°C for 10 hours. Upon completion of the reaction, methanol was removed by rotary evaporation and 100 mL of water was added to the residue and slowly neutralized with saturated sodium bicarbonate solution to pH=8, at which point a large amount of solid precipitated. The suspension was allowed to stand in an ice bath at 0 °C for 3 h to promote complete crystallization. This was followed by diafiltration and the solid product was washed with distilled water to remove inorganic salts. The resulting solid was dried and recrystallized using a mixed solvent of ethyl acetate/petroleum ether to give 30.8 g of methyl 7-azaindole-3-carboxylate in 87.6% yield.

References

[1] Patent: CN106588921, 2017, A. Location in patent: Paragraph 0018; 0019; 0024; 0026; 0028; 0030

1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate 808137-94-2
Price: US $2.20-8.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons
Release date: 2025-07-08

Career Henan Chemical Co

Product: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester 808137-94-2
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-08-05

808137-94-2, 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl esterRelated Search:

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Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate, 3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine

1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester

Methyl 1H-pyrrolo[2,3-b]pyridine-3-carbo×ylate

Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate

Methyl 7-azaindole-3-carboxylate

Methyl 7-azaindole-3-carb...

Methyl 7-

Methyl 7-azaindole-3-carboxylate 97%

SWF-99

SW-99

808137-94-2

Heterocycle-Pyridine series