1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester
Uses- Product Name
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester
- CAS No.
- 808137-94-2
- Chemical Name
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester
- Synonyms
- SW-99;SWF-99;Methyl 7-;Methyl 7-azaindole-3-carb...;Methyl 7-azaindole-3-carboxylate;Methyl 7-azaindole-3-carboxylate 97%;Methyl 1H-pyrrolo[2,3-b]pyridine-3-carbo×ylate;Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate;1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester;Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate, 3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine
- CBNumber
- CB51872067
- Molecular Formula
- C9H8N2O2
- Formula Weight
- 176.17
- MOL File
- 808137-94-2.mol
1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Property
- Melting point:
- 57-59℃
- Density
- 1.324
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 12.30±0.40(Predicted)
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C9H8N2O2/c1-13-9(12)7-5-11-8-6(7)3-2-4-10-8/h2-5H,1H3,(H,10,11)
- InChIKey
- XYRUNIAHPKBUJT-UHFFFAOYSA-N
- SMILES
- C12NC=C(C(OC)=O)C1=CC=CN=2
Safety
- HS Code
- 2933992000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M321415
- Product name
- Methyl1H-Pyrrolo[2,3-b]pyridine-3-carboxylate
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 4H23-1-M5
- Product name
- Methyl 7-azaindole-3-carboxylate
- Packaging
- 1g
- Price
- $99
- Updated
- 2021/12/16
- Product number
- CS-B0498
- Product name
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,methylester
- Packaging
- 5g
- Price
- $124
- Updated
- 2021/12/16
- Product number
- J51157
- Product name
- Methyl1H-pyrrolo[2,3-b]pyridine-3-carboxylate
- Packaging
- 5g
- Price
- $183
- Updated
- 2021/12/16
- Product number
- CS-B0498
- Product name
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,methylester
- Packaging
- 10g
- Price
- $245
- Updated
- 2021/12/16
1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Chemical Properties,Usage,Production
Uses
1H-pyrrolo[2,3-B]pyridine-3-carboxylic acid methyl ester is a carboxylic acid ester derivative that can be used as an organic synthesis intermediate and has a wide range of applications in the fields of medicine, food, pesticides, and daily chemicals.
Synthesis
4414-89-5
808137-94-2
(3) In a reaction flask, 100 mL of methanol and 100 mL of hydrochloric acid (10 mol/L) were added, and 28.6 g of 3-cyano-7-azaindole (0.2 mol) was dissolved in the mixed solvent, and the reaction was stirred for 10 hours at 80°C. The reaction was carried out at 80°C for 10 hours. Upon completion of the reaction, methanol was removed by rotary evaporation and 100 mL of water was added to the residue and slowly neutralized with saturated sodium bicarbonate solution to pH=8, at which point a large amount of solid precipitated. The suspension was allowed to stand in an ice bath at 0 °C for 3 h to promote complete crystallization. This was followed by diafiltration and the solid product was washed with distilled water to remove inorganic salts. The resulting solid was dried and recrystallized using a mixed solvent of ethyl acetate/petroleum ether to give 30.8 g of methyl 7-azaindole-3-carboxylate in 87.6% yield.
References
[1] Patent: CN106588921, 2017, A. Location in patent: Paragraph 0018; 0019; 0024; 0026; 0028; 0030
1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester Suppliers
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- Fax
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- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
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View Lastest Price from 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester manufacturers
- Product
- Methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate 808137-94-2
- Price
- US $2.20-8.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons
- Release date
- 2025-07-08
- Product
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester 808137-94-2
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-08-05