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N-(6-aminopyridin-2-yl)acetamide

Product Name
N-(6-aminopyridin-2-yl)acetamide
CAS No.
1075-62-3
Chemical Name
N-(6-aminopyridin-2-yl)acetamide
Synonyms
N-ACETYL-1,6-DIAMINOPYRIDINE;2-acetylamino-6-aminopyridine;N-(6-Aminopyridin-2-yl)acetamid;2-Acetamido-6-aminopyridine >N-(6-aminopyridin-2-yl)acetamide;N-(6-AMINO-2-PYRIDINYL)-ACETAMIDE;AcetaMide, N-(6-aMino-2-pyridinyl)-;N-(6-aminopyridin-2-yl)acetamide ISO 9001：2015 REACH
CBNumber
CB51991904
Molecular Formula
C7H9N3O
Formula Weight
151.17
MOL File
1075-62-3.mol
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N-(6-aminopyridin-2-yl)acetamide Property

Melting point:
158.0 to 162.0 °C
Boiling point:
419.4±30.0 °C(Predicted)
Density 
1.280±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
13.52±0.70(Predicted)
color 
White to Almost white
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Safety

HS Code 
2933.39.9200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2707
Product name
2-Acetamido-6-aminopyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$96
Updated
2025/07/31
TCI Chemical
Product number
A2707
Product name
2-Acetamido-6-aminopyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$313
Updated
2024/03/01
TRC
Product number
A168353
Product name
2-Acetamido-6-aminopyridine
Packaging
500mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
1571AA
Product name
N-(6-Aminopyridin-2-yl)acetamide
Packaging
10g
Price
$154
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA150997
Product name
N-Acetyl-1,6-diaminopyridine
Packaging
250mg
Price
$160
Updated
2021/12/16
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N-(6-aminopyridin-2-yl)acetamide Chemical Properties,Usage,Production

Synthesis

141-86-6

75-36-5

1075-62-3

GENERAL STEPS: Preparation of N-(6-aminopyridin-2-yl)acetamide; 2,6-diaminopyridine (9.822 g, 90 mmol) was dissolved in dioxane (100 mL) and cooled to 0 °C. Acetyl chloride (2.355 g, 2.1 mL, 30 mmol) was added slowly dropwise and stirred at 0 °C for 1 hour. The ice bath was removed and the reaction mixture was allowed to stir overnight at room temperature. Upon completion of the reaction, the reaction was quenched with saturated NaHCO3 solution and subsequently extracted three times with ethyl acetate. The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure to give the crude product. Purification by silica gel column chromatography using 60-70% ethyl acetate/hexane gradient elution afforded the target compound N-(6-aminopyridin-2-yl)acetamide (3.45 g, 76% yield). Mass spectrum (ESI-MS): m/z = 152.1 [M+H]+; 1H NMR (CDCl3, ppm): δ 7.49 (m, 3H), 6.28 (d, 1H), 4.31 (s, br, 2H), 2.19 (s, 3H).

References

[1] Journal of Organic Chemistry, 2014, vol. 79, # 2, p. 711 - 719
[2] Patent: WO2005/35499, 2005, A1. Location in patent: Page/Page column 46
[3] Journal of the American Chemical Society, 2016, vol. 138, # 50, p. 16228 - 16231
[4] Journal of the American Chemical Society, 1947, vol. 69, p. 1147,1148

N-(6-aminopyridin-2-yl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(6-aminopyridin-2-yl)acetamide Suppliers

Americas 1 China 63 Europe 1 Germany 1 India 3 Japan 1 The Netherlands 1 United Kingdom 1 United States 11 Global 83
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from N-(6-aminopyridin-2-yl)acetamide manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
N-(6-Aminopyridin-2-yl)acetamid 1075-62-3
Price
US $8.80-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2025-09-16
WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-(6-aminopyridin-2-yl)acetamide 1075-62-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-24
WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-(6-aminopyridin-2-yl)acetamide 1075-62-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-24

1075-62-3, N-(6-aminopyridin-2-yl)acetamideRelated Search:

2,6-DIACETYLAMINOPYRIDINE N-(6-aminopyridin-2-yl)acetamide N-[6-(2,2-DIMETHYL-PROPIONYLAMINO)-PYRIDIN-2-YL]-2,2-DIMETHYL-PROPIONAMIDE 5,6-DIAMINO-3-METHYL-2-OXO-8-PIPERIDIN-1-YL-2,3-DIHYDRO-1H-PYRROLO[2,3-C]-2,7-NAPHTHYRIDINE-9-CARBONITRILE 4,6-DIAMINO-1-(4-METHOXY-PHENYL)-2-OXO-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBONITRILE AURORA KA-3603 4,6-DIAMINO-1-(4-FLUORO-PHENYL)-2-OXO-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBONITRILE 7-AMINO-4-METHYL-1H-[1,8]NAPHTHYRIDIN-2-ONE 1-[6-(3,3-DIMETHYL-2-OXO-1-AZETANYL)-2-PYRIDINYL]-3,3-DIMETHYL-2-AZETANONE AURORA KA-3607 N-(6-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)-2-PYRIDINYL)-3-(TRIFLUOROMETHYL)BENZENECARBOXAMIDE 4,6-DIAMINO-2-OXO-1-PHENYL-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBONITRILE N-(6-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)-2-PYRIDINYL)-4-METHYLBENZENECARBOXAMIDE AURORA KA-3605 4,6-DIAMINO-1-(4-CHLORO-PHENYL)-2-OXO-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBONITRILE 3,4-DICHLORO-N-(6-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)-2-PYRIDINYL)BENZENECARBOXAMIDE 2,4-BIS(PROPYLAMIDO)PYRIDINE AURORA KA-3606

  • N-(6-aminopyridin-2-yl)acetamide
  • N-ACETYL-1,6-DIAMINOPYRIDINE
  • 2-acetylamino-6-aminopyridine
  • AcetaMide, N-(6-aMino-2-pyridinyl)-
  • N-(6-AMINO-2-PYRIDINYL)-ACETAMIDE
  • 2-Acetamido-6-aminopyridine &gt
  • N-(6-aminopyridin-2-yl)acetamide ISO 9001：2015 REACH
  • N-(6-Aminopyridin-2-yl)acetamid
  • 1075-62-3