Benzylmagnesium chloride Property

Boiling point:

182 °C(Press: 16 Torr)

Density 

1.031 g/mL at 25 °C

Flash point:

1 °F

storage temp. 

water-free area

form 

Liquid

color 

Brown to purple

Water Solubility 

Severe reaction

Sensitive 

Air & Moisture Sensitive

BRN 

878506

InChIKey

NRAFPLGJPPJUNB-UHFFFAOYSA-M

CAS DataBase Reference

6921-34-2(CAS DataBase Reference)

EPA Substance Registry System

Magnesium, chloro(phenylmethyl)- (6921-34-2)

Safety

Hazard Codes 

F+,C,Xi,F

Risk Statements 

12-14-34-66-67-36/37-19-11-14/15-40-37-17-22

Safety Statements 

16-29-33-7/8-45-43-36/37/39-26-6A-43B

RIDADR 

UN 2924 3/PG 2

WGK Germany 

1

F 

1-3-10

TSCA 

Yes

HazardClass 

4.3

PackingGroup 

II

HS Code 

29319090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H303May be harmfulif swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H333May be harmful if inhaled

H335May cause respiratory irritation

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H371May cause damage to organs

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

Benzylmagnesium chloride Chemical Properties,Usage,Production

Chemical Properties

Light gray to dark amber-grey slurry or solution

Uses

Benzyl magnesium chloride is used as a Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF). It is also used as organic chemical synthesis intermediate.

Uses

Benzylmagnesium chloride (Grignard reagent) can be used as an alkylating reagent:

• For alkylating quinolyl-functionalized Cp?chromium(III) complexes which are used as precursors for the preparation of active olefin polymerization catalysts.
• In the synthesis of 2,3-disubstituted benzopyran-4-ones, 6-chloro-8-methylpurine derivative, and phenylalanine derivatives.

Application

Benzylmagnesium chloride (Grignard reagent) can be used as an alkylating reagent:
For alkylating quinolyl-functionalized Cp?chromium(III) complexes which are used as precursors for the preparation of active olefin polymerization catalysts.
In the synthesis of 2,3-disubstituted benzopyran-4-ones, 6-chloro-8-methylpurine derivative, and phenylalanine derivatives.

General Description

This product has been enhanced for energy efficiency.

Research

Grignard reagents are organometallic compounds discovered by a French chemist, Victor Grignard in 1900. These compounds can be obtained as a formula “RMgX” by the reaction of halogenated hydrocarbons with magnesium metal in anhydrous solvents such as diethyl ether,1) and have been widely used in organic synthesis.
Grignard reagents are usually used as solutions, and they are typically grayish white ~ light brown clear solutions. They generally exist in an equilibrium between alkyl magnesium halides (RMgX) and dialkyl magnesium (R2Mg), which form equilibrium mixtures with complicated compositions (called “Schlenk equilibrium”).2) Furthermore, some of these species may cause precipitation due to their lower solubility. However, there is no problem in actual use.
In the case of precipitation being formed:
Please use it after gently shaking the bottle to fully disperse the suspension (If the amount of precipitation is very small, you can use the top clear layer of the suspension). Especially in cold conditions such as in winter, a large amount of precipitate may frequently form. In this case, please use it after crushing the solid with a dried glass stick. Alternatively, you can also use it the following. The bottle is put into a plastic bag and soaking in a water bath with warming at 40 degree C to dissolve the solid. Please be careful of volatilization of the organic solvent when the bottle is unsealing.

Precautions

It reacts violently with water. Air & moisture sensitive. Incompatible with oxidizing agents and bases.