4-Hydroxybenzylamine

Product Name: 4-Hydroxybenzylamine
CAS No.: 696-60-6
Chemical Name: 4-Hydroxybenzylamine
Synonyms: 4-(AMINOMETHYL)PHENOL;4-HOBA;AI320348;AI3 20348;AI3-20348;NSC 125720;RARECHEM AL BW 0048;4-HYDROXYBENZYLAMINE;Bisoprolol Impurity 26;Phenol, 4-(aminomethyl)-
CBNumber: CB5207547
Molecular Formula: C7H9NO
Formula Weight: 123.15
MOL File: 696-60-6.mol

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4-Hydroxybenzylamine Property

Melting point:: 123-128 °C
Boiling point:: 262.4±15.0 °C(Predicted)
Density: 1.141±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO (Slightly), Water (Slightly, Heated)
pka: 8.93±0.26(Predicted)
form: Powder
color: Off-white to pale yellow
InChIKey: RQJDUEKERVZLLU-UHFFFAOYSA-N
LogP: 0.350 (est)
CAS DataBase Reference: 696-60-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 34-36/37/38
Safety Statements: 26-36/37/39-24/25
RIDADR: 2735
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT, CORROSIVE
HS Code: 29214990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 776505
Product name: 4-Hydroxybenzylamine
Packaging: 5g
Price: $69.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 776505
Product name: 4-Hydroxybenzylamine
Packaging: 25g
Price: $102
Updated: 2024/03/01

TCI Chemical

Product number: A2305
Product name: 4-(Aminomethyl)phenol
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 25398
Product name: 4-HOBA
Packaging: 10g
Price: $53
Updated: 2024/03/01

Cayman Chemical

Product number: 25398
Product name: 4-HOBA
Packaging: 25g
Price: $82
Updated: 2024/03/01

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4-Hydroxybenzylamine Chemical Properties,Usage,Production

Description

4-HOBA is an isomer of the isoketal scavenger 2-HOBA that has reduced efficacy as an isoketal scavenger. Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II in mice. 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.

Chemical Properties

4-Hydroxybenzylamine, also known as tyramine and p-hydroxyphenethylamine, is a white or off-white or light green solid. Tyramine, a compound originally isolated from ergot alkaloids and decomposed animal tissues, is an important synthetic drug intermediate.

Uses

4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis.

Preparation

Synthesis of 4-Hydroxybenzylamine:Ammonia is passed into 500 ml of ethanol at 10° C. until saturation is reached, 122.1 g=1 mole of p-hydroxybenzaldehyde, 20 g of Raney nickel and 0.1 ml of concentrated sulfuric acid are added and the mixture is stirred in an autoclave for 6 hours at room temperature and under a hydrogen pressure of 100 atmospheres. After releasing the pressure, the catalyst is filtered off and the filtrate is boiled up with active charcoal, filtered and concentrated. The residue is recrystallized from a mixture of ethanol and ether. This gives 104 g (85% of theory), melting point: 104° C.
Literature source US04391805

Definition

ChEBI: 4-Hydroxybenzylamine is an aromatic amine.

target

GABA Receptor

4-Hydroxybenzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxybenzylamine Suppliers

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View Lastest Price from 4-Hydroxybenzylamine manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Hydroxybenzylamine 696-60-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Hydroxybenzylamine 696-60-6
Price: US $1.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-20

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Hydroxybenzylamine 696-60-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

696-60-6, 4-HydroxybenzylamineRelated Search:

Itopride Impurity C Itopride Impurity A Itopride N-Oxide ETHYL 3,4-DIMETHOXYBENZOATE NA 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE 3,4-DIMETHOXYBENZOYL CHLORIDE Itopride Impurity 1 2-(p-tolyloxy)-N,N-dimethylethanamine hydrochloride Benzaldehyde, 4-[2-(diMethylaMino)ethoxy]-, oxiMe Benzoic acid, 3,4-dimethoxy-, 4-formylphenyl ester Itopride Impurity B DL-LAUDANOSINE 3,4-Dichlorobenzylamine Veratrylamine 4-Ethoxybenzamide 4-Methoxybenzamide 1-Benzylpiperazine

RARECHEM AL BW 0048

4-HYDROXYBENZYLAMINE[4-(AMINOMETHYL)PHENOL]

4-(AMINOMETHYL)PHENOL

4-HYDROXYBENZYLAMINE

4-Hydroxybenzylamine, (4-Hydroxyphenyl)methylamine

4-(aminomethyl)phenol hydrochloride

4-Hydroxybenzylamine monohydrate, 97%

[(4-Hydroxyphenyl)Methyl]aMine

4-HydroxybenzeneMethanaMine

NSC 125720

p-HydroxybenzeneMethanaMine

4-HydroxybenzylaMine hydrate, 97%

4-Hydroxybenzylamine, 97.5%

4-HOBA

4-(Aminomethyl)phenol &gt

Phenol, 4-(aminomethyl)-

Bisoprolol Impurity 26

TIANFU-CHEM_Phenol,4-(aminomethyl)- 696-60-6

AI3 20348

AI320348

AI3-20348

696-60-6

Amines

Aromatics

Intermediates

Anilines, Aromatic Amines and Nitro Compounds