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H-CHA-OME HCL

Product Name
H-CHA-OME HCL
CAS No.
17193-39-4
Chemical Name
H-CHA-OME HCL
Synonyms
H-CHA-OME HCL;H-Cha-OMe hydrochloride;H-CHA-OME HCL USP/EP/BP;H-L-Cha-OMe hydrochloride;H-β-Cyclohexyl-Ala-OMe · HCl;H-beta-Cyclohexyl-Ala-OMe·HCl;L-CYCLOHEXYLALANINE METHYL ESTER HCL;L-CYCLOHEXYLALANINEMETHYLESTERHYDROCHLOERIDE;Methyl (S)-a-amino-cyclohexanepropanoate HCl;L-3-Cyclohexyl Alanine methyl ester Hydrochloride
CBNumber
CB5212974
Molecular Formula
C10H20ClNO2
Formula Weight
221.72
MOL File
17193-39-4.mol
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H-CHA-OME HCL Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Solid
color 
White to off-white
optical activity
20.8°(C=0.01g/ml MEOH)
InChI
InChI=1/C10H19NO2.ClH/c1-13-10(12)9(11)7-8-5-3-2-4-6-8;/h8-9H,2-7,11H2,1H3;1H/t9-;/s3
InChIKey
YLESODBCBYZUCT-OVMXBOEKNA-N
SMILES
C(OC)(=O)[C@H](CC1CCCCC1)N.[H]Cl |&1:4,r|
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS85243-2S
Product name
(S)-Methyl 2-amino-3-cyclohexylpropanoate HCl
Purity
97+% ee
Packaging
1g
Price
$16
Updated
2021/12/16
Activate Scientific
Product number
AS85243-2S
Product name
(S)-Methyl 2-amino-3-cyclohexylpropanoate HCl
Purity
97+% ee
Packaging
5G
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC107940
Product name
H-beta-Cyclohexyl-Ala-OMe·HCl
Packaging
1g
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC107940
Product name
H-beta-Cyclohexyl-Ala-OMe·HCl
Packaging
2g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC107940
Product name
H-beta-Cyclohexyl-Ala-OMe·HCl
Packaging
5G
Price
$150
Updated
2021/12/16
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H-CHA-OME HCL Chemical Properties,Usage,Production

Uses

H-beta-Cyclohexyl-Ala-OMe·HCl is used in the preparation of novel fluoropeptidomimetics, which are potential protease inhibitors.

Synthesis

67-56-1

25528-71-6

17193-39-4

For the synthesis of compounds 2a, 2c-2g, a slightly modified literature method [1] was used. The procedure was as follows: (S)-2-amino-3-cyclohexylpropanoic acid hydrochloride (32.2 mmol) was dissolved in anhydrous methanol (100 mL) under stirring conditions, and the temperature of the reaction system was maintained between -10 and -5 °C, and thionyl chloride (64.4 mmol) was added slowly dropwise. After the dropwise addition, the reaction mixture was stirred continuously at room temperature for 16 hours. After completion of the reaction, the reaction solution was concentrated to dryness by rotary evaporator. The resulting crude product was dissolved with ethyl acetate (EtOAc) and the solid product was subsequently collected by filtration. The collected solid was dried under reduced pressure to afford (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride as a white crystalline powder, all in higher than 80% yield. The melting point of the product and the 1H and 13C NMR spectroscopic data in D2O were in agreement with those reported in the literature [20] for the characterization of the compound.

References

[1] European Journal of Medicinal Chemistry, 2013, vol. 68, p. 253 - 259

H-CHA-OME HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-CHA-OME HCL Suppliers

China 79 India 3 Japan 2 United Kingdom 3 United States 9 Global 96
Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel
0523-86132544 15366717810
Fax
0523-86201489
Email
sales@thbiochem.com
Country
China
ProdList
370
Advantage
55
YangZhou Ruihong Biotech Co., Ltd.
Tel
0514-015380367604 15380367604
Fax
0514-83828236
Email
sales@ruibobiotech.com
Country
China
ProdList
511
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8258
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
BePharm Ltd
Tel
400-685-9117
Fax
021-51816740
Email
market@bepharm.com
Country
China
ProdList
15081
Advantage
60
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View Lastest Price from H-CHA-OME HCL manufacturers

Career Henan Chemical Co
Product
H-CHA-OME HCL 17193-39-4
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-09

17193-39-4, H-CHA-OME HCLRelated Search:

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  • 3-CYCLOHEXYL-L-ALANINE METHYL ESTER HYDROCHLORIDE
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  • H-β-Cyclohexyl-Ala-OMe · HCl
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  • 17193-39-4