β-Cyclohexyl-L-alanine methyl ester hydrochloride
- Product Name
- β-Cyclohexyl-L-alanine methyl ester hydrochloride
- CAS No.
- 17193-39-4
- Chemical Name
- β-Cyclohexyl-L-alanine methyl ester hydrochloride
- Synonyms
- H-CHA-OME HCL;H-Cha-OMe hydrochloride;H-CHA-OME HCL USP/EP/BP;H-L-Cha-OMe hydrochloride;H-β-Cyclohexyl-Ala-OMe · HCl;H-beta-Cyclohexyl-Ala-OMe·HCl;L-CYCLOHEXYLALANINE METHYL ESTER HCL;L-CYCLOHEXYLALANINEMETHYLESTERHYDROCHLOERIDE;Methyl (S)-a-amino-cyclohexanepropanoate HCl;L-3-Cyclohexyl Alanine methyl ester Hydrochloride
- CBNumber
- CB5212974
- Molecular Formula
- C10H20ClNO2
- Formula Weight
- 221.72
- MOL File
- 17193-39-4.mol
β-Cyclohexyl-L-alanine methyl ester hydrochloride Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Solid
- color
- White to off-white
- optical activity
- 20.8°(C=0.01g/ml MEOH)
- InChI
- InChI=1/C10H19NO2.ClH/c1-13-10(12)9(11)7-8-5-3-2-4-6-8;/h8-9H,2-7,11H2,1H3;1H/t9-;/s3
- InChIKey
- YLESODBCBYZUCT-OVMXBOEKNA-N
- SMILES
- C(OC)(=O)[C@H](CC1CCCCC1)N.[H]Cl |&1:4,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- HAA9525
- Product name
- methyl (S)-2-amino-3-cyclohexylpropanoate hydrochloride
- Packaging
- 5g
- Price
- $348
- Updated
- 2026/05/19
- Product number
- HAA9525
- Product name
- methyl (S)-2-amino-3-cyclohexylpropanoate hydrochloride
- Packaging
- 25g
- Price
- $1320
- Updated
- 2026/05/19
- Product number
- M54213
- Product name
- (S)-Methyl 2-amino-3-cyclohexylpropanoate hydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $61
- Updated
- 2026/05/06
- Product number
- M54213
- Product name
- (S)-Methyl 2-amino-3-cyclohexylpropanoate hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $67
- Updated
- 2026/05/06
- Product number
- M54213
- Product name
- (S)-Methyl 2-amino-3-cyclohexylpropanoate hydrochloride
- Purity
- 97%
- Packaging
- 10g
- Price
- $69
- Updated
- 2026/05/06
β-Cyclohexyl-L-alanine methyl ester hydrochloride Chemical Properties,Usage,Production
Uses
H-beta-Cyclohexyl-Ala-OMe·HCl is used in the preparation of novel fluoropeptidomimetics, which are potential protease inhibitors.
Synthesis
67-56-1
25528-71-6
17193-39-4
For the synthesis of compounds 2a, 2c-2g, a slightly modified literature method [1] was used. The procedure was as follows: (S)-2-amino-3-cyclohexylpropanoic acid hydrochloride (32.2 mmol) was dissolved in anhydrous methanol (100 mL) under stirring conditions, and the temperature of the reaction system was maintained between -10 and -5 °C, and thionyl chloride (64.4 mmol) was added slowly dropwise. After the dropwise addition, the reaction mixture was stirred continuously at room temperature for 16 hours. After completion of the reaction, the reaction solution was concentrated to dryness by rotary evaporator. The resulting crude product was dissolved with ethyl acetate (EtOAc) and the solid product was subsequently collected by filtration. The collected solid was dried under reduced pressure to afford (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride as a white crystalline powder, all in higher than 80% yield. The melting point of the product and the 1H and 13C NMR spectroscopic data in D2O were in agreement with those reported in the literature [20] for the characterization of the compound.
References
[1] European Journal of Medicinal Chemistry, 2013, vol. 68, p. 253 - 259
β-Cyclohexyl-L-alanine methyl ester hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
β-Cyclohexyl-L-alanine methyl ester hydrochloride Suppliers
- Tel
- 0523-86132544 15366717810
- Fax
- 0523-86201489
- sales@thbiochem.com
- Country
- China
- ProdList
- 389
- Advantage
- 55
- Tel
- 0514-015380367604 15380367604
- Fax
- 0514-83828236
- sales@ruibobiotech.com
- Country
- China
- ProdList
- 511
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44802
- Advantage
- 61
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9276
- Advantage
- 66
- Tel
- 400-6009262 15618770481
- Fax
- 021-64823266
- yhx@titansci.com
- Country
- China
- ProdList
- 14100
- Advantage
- 59
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- +86-21-61263340; 17609490614 13764994101
- Fax
- 021-61263399
- fisherwang@glschina.com
- Country
- China
- ProdList
- 8252
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 89686
- Advantage
- 60
- Tel
- 400-685-9117
- Fax
- 021-51816740
- market@bepharm.com
- Country
- China
- ProdList
- 15081
- Advantage
- 60
- Tel
- 0512-53995928 13862342518
- Fax
- 0512-53995928
- fyju@sxbiochem.com
- Country
- China
- ProdList
- 200
- Advantage
- 58
View Lastest Price from β-Cyclohexyl-L-alanine methyl ester hydrochloride manufacturers
- Product
- H-CHA-OME HCL 17193-39-4
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-09