TANDUTINIB

Product Name: TANDUTINIB
CAS No.: 228266-40-8
Chemical Name: TANDUTINIB
Synonyms: CS-1371;Spa 110;Hti 286;Taltobulin;Unii-J6D6912bxs;HTI-286;SPA-110;Taltobulin (HTI-286);HTI-286 hydrochloride;SPA-110 hydrochloride;HTI-286 HYDROCHLORIDE;SPA-110 HYDROCHLORIDE
CBNumber: CB52131222
Molecular Formula: C27H43N3O4
Formula Weight: 473.66
MOL File: 228266-40-8.mol

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TANDUTINIB Property

Melting point:: 135-137 ºC
Boiling point:: 662.4±55.0 °C(Predicted)
Density: 1.063
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: 40 mg/ml
form: A solid
pka: 4.68±0.19(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-3299
Product name: Taltobulin
Purity: 99.90%
Packaging: 5mg
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-3299
Product name: Taltobulin
Purity: 99.90%
Packaging: 10mg
Price: $240
Updated: 2021/12/16

ChemScene

Product number: CS-3299
Product name: Taltobulin
Purity: 99.90%
Packaging: 50mg
Price: $850
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0005326
Product name: TALTOBULIN
Purity: 95.00%
Packaging: 25G
Price: $1115.73
Updated: 2021/12/16

Crysdot

Product number: CD31002593
Product name: Taltobulin
Purity: 98+%
Packaging: 10mg
Price: $277
Updated: 2021/12/16

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TANDUTINIB Chemical Properties,Usage,Production

Uses

Treatment of solid tumors.

in vivo

Taltobulin (HTI-286; 1.6 mg/kg i.v.) inhibits the growth of human tumor xenografts (e.g., HCT-15, DLD-1, MX-1W, and KB-8-5) in athymic nu/nu female mice^[1].
Taltobulin (HTI-286; 3 mg/kg; p.o. gavage) inhibits growth by 97.3 % and 82% in athymic nu/nu female mice with Lox melanoma xenografts and KB-3-1 epidermoid xenograft model, respectively^[1].

Animal Model:	Athymic nu/nu female mice with Lox melanoma model (5-6 weeks of age)^[1]
Dosage:	1.6 mg/kg
Administration:	Administered i.v.;for 35 days
Result:	Growth of Lox tumors was inhibited by 96-98% on day 12 compared with vehicle-treated controls. Growth of KB-8-5 tumors was inhibited by 84% on day 14 compared with vehicle-treated controls. Growth of MX-1W tumors was inhibited by 97% compared with vehicle-treated controls. Growth of DLD-1 and HCT-15 tumors was inhibited by 80 and 66%, respectively.

IC 50

Traditional Cytotoxic Agents

TANDUTINIB Preparation Products And Raw materials

Raw materials

Preparation Products

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TANDUTINIB Suppliers

China 64 Japan 1 United States 11 Global 76

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Alabiotech Inc.

Tel: 001-619-354-5251
Fax: 001-855-855-6087
Email: sales@alabiotech-e.com
Country: United States
ProdList: 972
Advantage: 60

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View Lastest Price from TANDUTINIB manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Taltobulin 228266-40-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Taltobulin 228266-40-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

228266-40-8, TANDUTINIBRelated Search:

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228266-40-8

C27H43N3O4