ChemicalBook > CAS DataBase List > (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
- Product Name
- (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
- CAS No.
- 3796-63-2
- Chemical Name
- (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
- Synonyms
- 9E;E-0671;13E)-Teprenone;Zanamivir Impurity 13;13E)-Geranylgeranylacetone;(5E,9E,13E)-Geranylgeranylacetone;(5E,9E,13E) Teprenone,(5E,9E,13E)Teprenone;(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one;(5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one;5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (E,E,E)-
- CBNumber
- CB52174184
- Molecular Formula
- C23H38O
- Formula Weight
- 330.55
- MOL File
- 3796-63-2.mol
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(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Property
- Boiling point:
- 442.2±24.0 °C(Predicted)
- Density
- 0.872±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 5 mg/mL (15.13 mM)
- form
- Liquid
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
TRC
- Product number
- T103505
- Product name
- (5E,9E,13E)-Teprenone
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
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(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Chemical Properties,Usage,Production
Uses
(5E,9E,13E)-Teprenone is an isomer of Teprenone (T103500), An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Reports indicate that Teprenone protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression.
Definition
ChEBI: Teprenone is a terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio). It has a role as an anti-ulcer drug, a cardioprotective agent, a hepatoprotective agent, a nephroprotective agent, a neuroprotective agent and a Hsp70 inducer. It is a methyl ketone and a terpene ketone. It contains a geranylgeranyl group.
in vivo
(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa[1].
| Animal Model: | Male Wister strain rats (≈250 g)[1] |
| Dosage: | 200 mg/kg |
| Administration: | Oral administration |
| Result: | Caused accumulations of all of HSP90, HSP70, HSC70 and HSP60 within 60 minutes. |
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Preparation Products And Raw materials
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Preparation Products
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(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Suppliers
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View Lastest Price from (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one 3796-63-2
- Price
- US $880.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 1T
- Release date
- 2020-07-06
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