(R)-(+)-Ketorolac
- Product Name
- (R)-(+)-Ketorolac
- CAS No.
- 66635-93-6
- Chemical Name
- (R)-(+)-Ketorolac
- Synonyms
- (1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+)-Ketorolac;(R)-Ketorolac;(R)-(+)-Ketorolac;Ketorolac R-IsoMer;(R)-Ketorolac [(+)-Ketorolac);(R)-(+)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 1/Ketorolac R-Isomer;(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
- CBNumber
- CB52226607
- Molecular Formula
- C15H13NO3
- Formula Weight
- 255.27
- MOL File
- 66635-93-6.mol
(R)-(+)-Ketorolac Property
- Melting point:
- 163-170°C
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +162 to +178°, c = 1 in methanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML1654
- Product name
- R-Ketorolac
- Purity
- ≥95% (HPLC)
- Packaging
- 5MG
- Price
- $238
- Updated
- 2023/06/20
- Product number
- SML1654
- Product name
- R-Ketorolac
- Purity
- ≥95% (HPLC)
- Packaging
- 25MG
- Price
- $953
- Updated
- 2023/06/20
- Product number
- K235600
- Product name
- (R)-Ketorolac
- Packaging
- 100mg
- Price
- $1620
- Updated
- 2021/12/16
- Product number
- K235600
- Product name
- (R)-Ketorolac
- Packaging
- 50mg
- Price
- $920
- Updated
- 2021/12/16
- Product number
- API0010456
- Product name
- (+)-KETOROLAC
- Purity
- 95.00%
- Packaging
- 2MG
- Price
- $350
- Updated
- 2021/12/16
(R)-(+)-Ketorolac Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Definition
ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
Biochem/physiol Actions
R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.
(R)-(+)-Ketorolac Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-(+)-Ketorolac manufacturers
- Product
- (R)-(+)-Ketorolac 66635-93-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13