(R)-(+)-Ketorolac

Product Name: (R)-(+)-Ketorolac
CAS No.: 66635-93-6
Chemical Name: (R)-(+)-Ketorolac
Synonyms: (1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+)-Ketorolac;(R)-Ketorolac;(R)-(+)-Ketorolac;Ketorolac R-IsoMer;(R)-Ketorolac [(+)-Ketorolac);(R)-(+)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 1/Ketorolac R-Isomer;(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
CBNumber: CB52226607
Molecular Formula: C15H13NO3
Formula Weight: 255.27
MOL File: 66635-93-6.mol

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(R)-(+)-Ketorolac Property

Melting point:: 163-170°C
storage temp.: -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: powder
color: white to beige
optical activity: [α]/D +162 to +178°, c = 1 in methanol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1654
Product name: R-Ketorolac
Purity: ≥95% (HPLC)
Packaging: 5MG
Price: $238
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1654
Product name: R-Ketorolac
Purity: ≥95% (HPLC)
Packaging: 25MG
Price: $953
Updated: 2023/06/20

TRC

Product number: K235600
Product name: (R)-Ketorolac
Packaging: 100mg
Price: $1620
Updated: 2021/12/16

TRC

Product number: K235600
Product name: (R)-Ketorolac
Packaging: 50mg
Price: $920
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010456
Product name: (+)-KETOROLAC
Purity: 95.00%
Packaging: 2MG
Price: $350
Updated: 2021/12/16

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(R)-(+)-Ketorolac Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.

Definition

ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.

Biochem/physiol Actions

R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.

(R)-(+)-Ketorolac Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-Ketorolac Suppliers

Canada 1 China 38 India 4 United States 5 Global 48

Shanghai Boyle Chemical Co., Ltd.

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J & K SCIENTIFIC LTD.

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ChemStrong Scientific Co.,Ltd

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Sigma-Aldrich

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Nanjing XiZe Biotechnology CO., Ltd.

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Tonichem Pharmaceutical Technology Co., Ltd.

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Shanghai CR Corporation Limited

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Aikon International Limited

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Email: lwan@aikonchem.com
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
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View Lastest Price from (R)-(+)-Ketorolac manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: (R)-(+)-Ketorolac 66635-93-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Dideu Industries Group Limited

Product: (R)-(+)-Ketorolac 66635-93-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-21

66635-93-6, (R)-(+)-KetorolacRelated Search:

(S)-Ketorolac Ketorolac Impurity 48 Ketorolac Impurity 43 Ketorolac Impurity 31 Ketorolac Impurity 24 (5-chloro-1H-pyrrol-2-yl)-phenylmethanone Ethyl 2-(1H-pyrrol-2-yl)acetate Ketorolac Related Compound A (20 mg) (5-benzoyl-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2,3-dihydro-1H-pyrrolizine-1-carboxamide) Ethyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic Ketorolac Impurity 54 4-HYDROXY KETOROLAC Ketorolac tromethamine Ketorolac Impurity 21 KETOROLAC EP IMPURITY H Ketorolac EP IMpurity D 1-Descarboxy Ketorolac Ketorolac EP IMpurity G 2,2'-BIPYRROL

Ketorolac R-IsoMer

(1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

Ketorolac impurity 1/Ketorolac R-Isomer

(R)-(+)-Ketorolac

(R)-Ketorolac

1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1R)-

(R)-(+)-Ketorolac ISO 9001：2015 REACH

(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

(R)-Ketorolac [(+)-Ketorolac)

(1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acidQ: What is (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the CAS Number of (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the storage condition of (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

(+)-Ketorolac

(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac

66635-93-6

Aromatics

Chiral Reagents

Heterocycles

Inhibitors

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