ChemicalBook > CAS DataBase List > 2-HYDROXY-5-NITROBENZYL BROMIDE
2-HYDROXY-5-NITROBENZYL BROMIDE
- Product Name
- 2-HYDROXY-5-NITROBENZYL BROMIDE
- CAS No.
- 772-33-8
- Chemical Name
- 2-HYDROXY-5-NITROBENZYL BROMIDE
- Synonyms
- KOSHLAND I;KOSHLAND REAGENT;KOSHLAND'S REAGENT;KOSHLAND'S REAGENT I;Koshland's reagent 1;Koshland's Reagent 1;α-bromo-4-nitro-o-creso;α-bromo-4-nitro-o-cresol;a-Bromo-4-nitro-o-cresol;α-bromo-4-nitro-o-cresol
- CBNumber
- CB5229370
- Molecular Formula
- C7H6BrNO3
- Formula Weight
- 232.03
- MOL File
- 772-33-8.mol
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2-HYDROXY-5-NITROBENZYL BROMIDE Property
- Melting point:
- 144-149 °C(lit.)
- Boiling point:
- 383.0±32.0 °C(Predicted)
- Density
- 1.795
- refractive index
- 1.6090 (estimate)
- storage temp.
- 2-8°C
- solubility
- chloroform: soluble25mg/mL, clear, yellow
- pka
- 6.16±0.30(Predicted)
- form
- Crystalline Powder
- color
- Beige to light brown
- BRN
- 1868798
- CAS DataBase Reference
- 772-33-8(CAS DataBase Reference)
- EPA Substance Registry System
- Phenol, 2-(bromomethyl)-4-nitro- (772-33-8)
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Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29089990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 162906
- Product name
- 2-Hydroxy-5-nitrobenzyl bromide
- Purity
- 90%
- Packaging
- 5g
- Price
- $68.9
- Updated
- 2024/03/01
TCI Chemical
- Product number
- H0601
- Product name
- 2-Hydroxy-5-nitrobenzyl Bromide
- Purity
- >95.0%(T)
- Packaging
- 5g
- Price
- $147
- Updated
- 2024/03/01
TRC
- Product number
- H950893
- Product name
- 2-Hydroxy-5-nitrobenzyl Bromide
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
Frontier Specialty Chemicals
- Product number
- JK247575
- Product name
- 2-Hydroxy-5-nitrobenzyl Bromide
- Purity
- 95%
- Packaging
- 5g
- Price
- $38
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0011683
- Product name
- 2-HYDROXY-5-NITRO BENZYL BROMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $830.74
- Updated
- 2021/12/16
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2-HYDROXY-5-NITROBENZYL BROMIDE Chemical Properties,Usage,Production
Chemical Properties
Beige to yellow crystalline powder
Uses
Reagent for sulfhydryl modification.1
Uses
2-Hydroxy-5-nitrobenzyl bromide is a chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules..
Uses
2-Hydroxy-5-nitrobenzyl bromide was used in covalent modification of tryptophan and tryptophan residues in monoclonal immunoglobulin. It was also used as reagent for sulfhydryl modification
Synthesis Reference(s)
Journal of the American Chemical Society, 86, p. 1448, 1964 DOI: 10.1021/ja01061a045
General Description
2-Hydroxy-5-nitrobenzyl bromide is a protein modifying reagent.
Purification Methods
Crystallise the bromide from *benzene or *benzene/ligroin. It is slightly soluble in EtOH, soluble in *C6H6 and AcOH, and very soluble in ligroin. [Beilstein 6 H 367.]
2-HYDROXY-5-NITROBENZYL BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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772-33-8, 2-HYDROXY-5-NITROBENZYL BROMIDERelated Search:
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