L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10

Product Name: L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10
CAS No.: 106972-44-5
Chemical Name: L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10
Synonyms: 15N, 97%);L-LEUCINE-D10;l-leucine-c-d10;L-LEUCINE (D10, 98%);L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d??;L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10, 98 AT OM % D;L-Leucine-2,3,3,4,5,5,5,5',5',5'-d10 98 atom % D;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10
CBNumber: CB5237298
Molecular Formula: C6H3D10NO2
Formula Weight: 141.23
MOL File: 106972-44-5.mol

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L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Property

Melting point:: >300 °C(lit.)
storage temp.: Refrigerator
solubility: Aqueous Acid (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
optical activity: [α]25/D +14.5°, c = 2 in 5 M HCl

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 492949
Product name: L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10
Purity: 98 atom % D
Packaging: 250mg
Price: $572
Updated: 2024/03/01

TRC

Product number: L330638
Product name: L-Leucine-d10
Packaging: 50mg
Price: $385
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BAR0003409
Product name: L-LEUCINE-D10
Purity: 95.00%
Packaging: 5MG
Price: $505.91
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: D429
Product name: L-Leucine-d10
Packaging: 100mg
Price: $590
Updated: 2021/12/16

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L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Chemical Properties,Usage,Production

Uses

L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. DOI:10.1371/journal.pgen.1003857
[3] Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. DOI:10.1186/1743-7075-9-77
[4] Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17. DOI:10.2337/db11-0765

L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Preparation Products And Raw materials

Raw materials

Preparation Products

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L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Suppliers

Canada 1 China 41 Germany 1 India 2 Japan 1 Switzerland 1 United States 6 Global 53

Artis Chemistry (Shanghai) Co. Ltd.

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Sigma-Aldrich

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106972-44-5, L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10Related Search:

DL-LEUCINE-2,3,3,4,5,5,5,6,6,6-D 10,DL-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10, 98 A TOM % D,dl-leucine-2,3,3,4,5,5,5,5',5',5'-d10 BUTANOL-D1 L-2-AMINOBUTYRIC-3,3-D2 ACID L-ALANINE-2-D1 DL-ALANINE-2-D1 L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 L-LEUCINE-2-D1 L-LEUCINE-5,5,5-D3 DL-LEUCINE-2-D1 PROPIONIC ACID-OD N-PENTYL-5,5,5-D3 ALCOHOL L-LEUCINE-3,3-D2 PENTANOIC-5,5,5-D3 ACID

L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10, 98 AT OM % D

l-leucine-c-d10

L-LEUCINE (D10, 98%)

L-LEUCINE-D10

L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10

15N, 97%)

L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10

L-Leucine-2,3,3,4,5,5,5,5',5',5'-d10 98 atom % D

L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d??

<sc>L</sc>-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d<sub>10</sub>

106972-44-5

CD32CDCD2CDNH2COOH

CD32CDCD2CDNH2CO2H

Stable Isotopes

BioChemical

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