ChemicalBook > CAS DataBase List > L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10

L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10

Product Name
L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10
CAS No.
106972-44-5
Chemical Name
L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10
Synonyms
15N, 97%);D10-L-Leucine;L-LEUCINE-D10;l-leucine-c-d10;L-LEUCINE (D10, 98%);L-Leucine (D??, 98%);L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d??;L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10, 98 AT OM % D
CBNumber
CB5237298
Molecular Formula
C6H3D10NO2
Formula Weight
141.23
MOL File
106972-44-5.mol
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L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Property

Melting point:
>300 °C(lit.)
storage temp. 
Refrigerator
solubility 
Aqueous Acid (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
optical activity
[α]25/D +14.5°, c = 2 in 5 M HCl
CAS Number Unlabeled
61-90-5
CAS Number Unlabeled
61-90-5
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
492949
Product name
L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10
Purity
98 atom % D
Packaging
250mg
Price
$598
Updated
2025/07/31
TRC
Product number
L330638
Product name
L-Leucine-d10
Packaging
50mg
Price
$385
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BAR0003409
Product name
L-LEUCINE-D10
Purity
95.00%
Packaging
5MG
Price
$505.91
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D429
Product name
L-Leucine-d10
Packaging
100mg
Price
$590
Updated
2021/12/16
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L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Chemical Properties,Usage,Production

Uses

L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. DOI:10.1371/journal.pgen.1003857
[3] Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. DOI:10.1186/1743-7075-9-77
[4] Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17. DOI:10.2337/db11-0765

L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Preparation Products And Raw materials

Raw materials

Preparation Products

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L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 Suppliers

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View Lastest Price from L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10 manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.
Product
L-Leucine-d10 106972-44-5
Price
US $1200.00-1100.00/ton
Min. Order
1ton
Purity
99%
Supply Ability
1000T/M
Release date
2025-11-04

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