ChemicalBook > CAS DataBase List > CCG-1423

CCG-1423

Product Name: CCG-1423
CAS No.: 285986-88-1
Chemical Name: CCG-1423
Synonyms: CCg;CS-1769;CCG-1423;CC -1423;CCG1423, >98%;CCG-1423 ，S7719;CCG 1423;CCG-1423;CCG-1423 USP/EP/BP;CCG-1423, 10 mM in DMSO;Rho/SRF Pathway Inhibitor, CCG-1423
CBNumber: CB52446676
Molecular Formula: C18H13ClF6N2O3
Formula Weight: 454.75
MOL File: 285986-88-1.mol

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CCG-1423 Property

storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: soluble5mg/mL, clear (warmed)
form: White solid
color: white to beige

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Safety

WGK Germany: 3
HS Code: 2924.29.7790

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0987
Product name: CCG-1423
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $143.45
Updated: 2025/07/31

Sigma-Aldrich

Product number: 555558
Product name: Rho/SRF Pathway Inhibitor, CCG-1423
Packaging: 25mg
Price: $236
Updated: 2025/07/31

TCI Chemical

Product number: C3449
Product name: CCG-1423
Purity: >98.0%(GC)
Packaging: 25mg
Price: $162
Updated: 2025/07/31

TCI Chemical

Product number: C3449
Product name: CCG-1423
Purity: >98.0%(GC)
Packaging: 100mg
Price: $484
Updated: 2025/07/31

Cayman Chemical

Product number: 10010350
Product name: CCG-1423
Purity: ≥98%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

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CCG-1423 Chemical Properties,Usage,Production

Uses

CCG-1423 is a specific RhoA pathway inhibitor, inhibiting SRF-mediated transcription which has been implicated in cancer and fibrosis.

Biological Activity

CCG-1423 is a potent and specific inhibitor of Rho pathway signaling and activation of serum response factor (SRF) transcription. CCG-1423 inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13. Also CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines.

in vivo

CCG-1423 (0.15 mg/kg; i.p. once daily for two weeks) affects glucose tolerance and insulin levels in HFD-fed mice^[1].

Animal Model:	16-week-old mice with HFD-induced obesity^[1]
Dosage:	0.15 mg/kg
Administration:	Intraperitoneal injection; 0.15 mg/kg once per day; for two weeks
Result:	Improved glucose tolerance and reduced insulin levels at 30 minutes after glucose injection.

storage

+4°C

CCG-1423 Preparation Products And Raw materials

Raw materials

Preparation Products

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CCG-1423 Suppliers

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View Lastest Price from CCG-1423 manufacturers

Career Henan Chemical Co

Product: N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide 285986-88-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20kg
Release date: 2019-09-05

285986-88-1, CCG-1423Related Search:

ML 141 Wnt-C59 PF-3758309 EHT1864 RG108 3,5-Di(trifluoromethyl)benzamide CCG-1423

CCG-1423

N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide

N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide

N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423

N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide

Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem

CCG 1423;CCG-1423

CCG1423, >98%

CS-1769

N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide

Rho/SRF Pathway Inhibitor, CCG-1423

CCg

Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-

CCG-1423 USP/EP/BP

CC -1423

CCG 1423, Rho pathway-mediated signaling inhibitor

CCG-1423, 10 mM in DMSO

CCG-1423 ，S7719

285986-88-1

C18H13ClF6N2O3

Inhibitors