4,5-DICHLORO-6-METHYLPYRIMIDINE

Product Name: 4,5-DICHLORO-6-METHYLPYRIMIDINE
CAS No.: 83942-10-3
Chemical Name: 4,5-DICHLORO-6-METHYLPYRIMIDINE
Synonyms: 4,5-DICHLORO-6-METHYLPYRIMIDINE;Pyrimidine, 4,5-dichloro-6-methyl-;4,5-Dichloro-6-methylpyrimidine 98%;4,5-DICHLORO-6-METHYLPYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB52452828
Molecular Formula: C5H4Cl2N2
Formula Weight: 163
MOL File: 83942-10-3.mol

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4,5-DICHLORO-6-METHYLPYRIMIDINE Property

Boiling point:: 242.6±35.0 °C(Predicted)
Density: 1.404±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.69±0.26(Predicted)
Appearance: Light yellow to yellow Solid-Liquid Mixture

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D435423
Product name: 4,5-Dichloro-6-methylpyrimidine
Packaging: 1g
Price: $310
Updated: 2021/12/16

AK Scientific

Product number: W8684
Product name: 4,5-Dichloro-6-methylpyrimidine
Packaging: 250mg
Price: $86
Updated: 2021/12/16

Matrix Scientific

Product number: 073700
Product name: 4,5-Dichloro-6-methylpyrimidine
Purity: 95+%
Packaging: 1g
Price: $185
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-QP
Product name: 4,5-Dichloro-6-methylpyrimidine
Purity: 95%
Packaging: 250mg
Price: $280
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD145633
Product name: 4,5-Dichloro-6-Methylpyrimidine
Packaging: 250mg
Price: $400
Updated: 2021/12/16

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4,5-DICHLORO-6-METHYLPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

7752-72-9

83942-10-3

2) Preparation of intermediate 4,5-dichloro-6-methylpyrimidine: 50 mL of phosphorus oxychloride (POCl3) was slowly added dropwise to 50 mL of toluene solution containing 14.5 g (0.1 mol) of 5-chloro-6-methylpyrimidin-4(1H)-one. After completion of the dropwise addition, the reaction mixture was heated to reflux for 5-7 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, toluene and excess TLC were removed by distillation under reduced pressure. Subsequently, the reaction mixture was carefully poured into ice water. The aqueous phase was extracted with ethyl acetate (3 x 50 mL), the organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Finally, the residue was purified by silica gel column chromatography to afford 14.43 g of the target product 4,5-dichloro-6-methylpyrimidine as a yellow liquid in 88.5% yield.

References

[1] Patent: US2015/225378, 2015, A1. Location in patent: Paragraph 0163; 0164
[2] Patent: EP2913325, 2015, A1. Location in patent: Paragraph 0453; 0454
[3] Patent: CN105348298, 2016, A. Location in patent: Paragraph 0421; 0422; 0423
[4] Patent: CN105732585, 2016, A. Location in patent: Paragraph 0371; 0372; 0373
[5] Patent: CN105777717, 2016, A. Location in patent: Paragraph 0360; 0361; 0362

4,5-DICHLORO-6-METHYLPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-DICHLORO-6-METHYLPYRIMIDINE Suppliers

China 58 Germany 1 India 1 United Kingdom 1 United States 6 Global 67

Pure Chemistry Scientific Inc.

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ShangHai AmK Pharmaceutical Technology Co., Ltd.

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View Lastest Price from 4,5-DICHLORO-6-METHYLPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 4,5-DICHLORO-6-METHYLPYRIMIDINE 83942-10-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-07

83942-10-3, 4,5-DICHLORO-6-METHYLPYRIMIDINERelated Search:

4,5-Dichlorosalicylaldehyde Benzaldehyde, 2,4-difluoro-6-hydroxy- (9CI) 4,5-DICHLORO-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE 4,5-DICHLORO-6-METHYL-2-[5-(TRIFLUOROMETHYL)-2-PYRIDYL]PYRIMIDINE 4,5-DICHLORO-6-TRIFLUOROMETHYLPYRIMIDINE 4,5-DICHLORO-6-DIFLUOROMETHYLPYRIMIDINE 4,5-DICHLORO-6-METHYL-2-PHENYLPYRIMIDINE 2,4,5-Trichloro-6-methylpyrimidine 4,5-DICHLORO-6-METHYL-2-(2-PYRIDYL)PYRIMIDINE 4,5-DICHLORO-6-METHYL-2-PYRIMIDINAMINE 4,5-Dichloro-6-ethylpyrimidine 4,5-DICHLORO-6-METHYL-2-(3-PYRIDYL)PYRIMIDINE 4,5-DICHLORO-6-ISOPROPYLPYRIMIDINE N-(4,5-DICHLORO-6-METHYL-2-PYRIMIDINYL)ACETAMIDE 4,5-DICHLORO-6-METHYLPYRIMIDINE

4,5-DICHLORO-6-METHYLPYRIMIDINE

Pyrimidine, 4,5-dichloro-6-methyl-

4,5-DICHLORO-6-METHYLPYRIMIDINE ISO 9001：2015 REACH

4,5-Dichloro-6-methylpyrimidine 98%

83942-10-3

Heterocycle-Pyrimidine series