2,4,8-TRICHLOROQUINAZOLINE

Product Name: 2,4,8-TRICHLOROQUINAZOLINE
CAS No.: 62484-29-1
Chemical Name: 2,4,8-TRICHLOROQUINAZOLINE
Synonyms: 2,4,8-TRICHLOROQUINAZOLINE;Quinazoline, 2,4,8-trichloro-
CBNumber: CB52464517
Molecular Formula: C8H3Cl3N2
Formula Weight: 233.48
MOL File: 62484-29-1.mol

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2,4,8-TRICHLOROQUINAZOLINE Property

Boiling point:: 309.1±24.0 °C(Predicted)
Density: 1.60
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.68±0.30(Predicted)
Appearance: White to yellow Solid

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 3H32-5-WJ
Product name: 2,4,8-Trichloroquinazoline
Purity: 97%
Packaging: 250mg
Price: $116
Updated: 2021/12/16

AK Scientific

Product number: Z4958
Product name: 2,4,8-Trichloroquinazoline
Packaging: 250mg
Price: $131
Updated: 2021/12/16

Apolloscientific

Product number: OR926964
Product name: 2,4,8-Trichloroquinazoline
Purity: 97%
Packaging: 1g
Price: $171
Updated: 2021/12/16

AK Scientific

Product number: Z4958
Product name: 2,4,8-Trichloroquinazoline
Packaging: 1g
Price: $253
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-WJ
Product name: 2,4,8-Trichloroquinazoline
Purity: 97%
Packaging: 1g
Price: $274
Updated: 2021/12/16

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2,4,8-TRICHLOROQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

62484-22-4

62484-29-1

General procedure for the synthesis of 2,4,8-trichloroquinazoline from 8-chloroquinazoline-2,4(1H,3H)-dione: (1041) To 8-chloroquinazoline-2,4(1H,3H)-dione (3.8 g, 19.33 mmol) was added 60 mL of phosphorus oxychloride (POCl3). The reaction mixture was heated to reflux for 16 hours. Upon completion of the reaction, the excess phosphorous trichloride was evaporated under reduced pressure and the residue was purified by column chromatography to afford 2,4,8-trichloroquinazoline (3.11 g, 76% yield). Mass spectrum (ESI+): m/z = 233 [M + 1].

References

[1] Patent: US2016/168140, 2016, A1. Location in patent: Paragraph 1041
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 10, p. 2297 - 2300
[3] Patent: US5688803, 1997, A
[4] Patent: EP2226315, 2010, A1. Location in patent: Page/Page column 33
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5141 - 5156

2,4,8-TRICHLOROQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,8-TRICHLOROQUINAZOLINE Suppliers

China 51 India 1 United States 6 Global 58

Shanghai Boyle Chemical Co., Ltd.

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View Lastest Price from 2,4,8-TRICHLOROQUINAZOLINE manufacturers

Career Henan Chemical Co

Product: 2,4,8-TRICHLOROQUINAZOLINE 62484-29-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-12

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