ChemicalBook > CAS DataBase List > 2,4,8-TRICHLOROQUINAZOLINE

2,4,8-TRICHLOROQUINAZOLINE

Product Name
2,4,8-TRICHLOROQUINAZOLINE
CAS No.
62484-29-1
Chemical Name
2,4,8-TRICHLOROQUINAZOLINE
Synonyms
2,4,8-TRICHLOROQUINAZOLINE;Quinazoline, 2,4,8-trichloro-
CBNumber
CB52464517
Molecular Formula
C8H3Cl3N2
Formula Weight
233.48
MOL File
62484-29-1.mol
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2,4,8-TRICHLOROQUINAZOLINE Property

Boiling point:
309.1±24.0 °C(Predicted)
Density 
1.60
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.68±0.30(Predicted)
Appearance
White to yellow Solid
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories
Product number
3H32-5-WJ
Product name
2,4,8-Trichloroquinazoline
Purity
97%
Packaging
250mg
Price
$116
Updated
2021/12/16
AK Scientific
Product number
Z4958
Product name
2,4,8-Trichloroquinazoline
Packaging
250mg
Price
$131
Updated
2021/12/16
Apolloscientific
Product number
OR926964
Product name
2,4,8-Trichloroquinazoline
Purity
97%
Packaging
1g
Price
$171
Updated
2021/12/16
AK Scientific
Product number
Z4958
Product name
2,4,8-Trichloroquinazoline
Packaging
1g
Price
$253
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-WJ
Product name
2,4,8-Trichloroquinazoline
Purity
97%
Packaging
1g
Price
$274
Updated
2021/12/16
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2,4,8-TRICHLOROQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

62484-22-4

62484-29-1

General procedure for the synthesis of 2,4,8-trichloroquinazoline from 8-chloroquinazoline-2,4(1H,3H)-dione: (1041) To 8-chloroquinazoline-2,4(1H,3H)-dione (3.8 g, 19.33 mmol) was added 60 mL of phosphorus oxychloride (POCl3). The reaction mixture was heated to reflux for 16 hours. Upon completion of the reaction, the excess phosphorous trichloride was evaporated under reduced pressure and the residue was purified by column chromatography to afford 2,4,8-trichloroquinazoline (3.11 g, 76% yield). Mass spectrum (ESI+): m/z = 233 [M + 1].

References

[1] Patent: US2016/168140, 2016, A1. Location in patent: Paragraph 1041
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 10, p. 2297 - 2300
[3] Patent: US5688803, 1997, A
[4] Patent: EP2226315, 2010, A1. Location in patent: Page/Page column 33
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5141 - 5156

2,4,8-TRICHLOROQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4,8-TRICHLOROQUINAZOLINE manufacturers

Career Henan Chemical Co
Product
2,4,8-TRICHLOROQUINAZOLINE 62484-29-1
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

62484-29-1, 2,4,8-TRICHLOROQUINAZOLINERelated Search:

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