ChemicalBook > CAS DataBase List > (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

Product Name: (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE
CAS No.: 112811-70-8
Chemical Name: (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE
Synonyms: Moxifloxacin Impurity Ⅷ;Azilsartan medoxomil impurity266;Moxifloxacin Intermediate Impurity 2;Moxifloxacin Intermediate Impurity 2 Control;Ethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylate;ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;Ethyl(Z)-3-(Cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE;(E)-ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;2-(2,4,5-Trifluoro-3-Methoxybenzoyl)-3-cyclopropylaMinoacrylic Acid Ethyl Ester
CBNumber: CB52468409
Molecular Formula: C16H16F3NO4
Formula Weight: 343.3
MOL File: 112811-70-8.mol

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(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Property

Boiling point:: 463.2±45.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
pka: 2.70±0.70(Predicted)
InChI: InChI=1S/C16H16F3NO4/c1-3-24-16(22)10(7-20-8-4-5-8)14(21)9-6-11(17)13(19)15(23-2)12(9)18/h6-8,20H,3-5H2,1-2H3/b10-7-
InChIKey: HVJXUGXNDLCTGC-YFHOEESVSA-N
SMILES: C(=C/NC1CC1)(\C(C1C(F)=C(OC)C(F)=C(F)C=1)=O)/C(=O)OCC

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T790730
Product name: 2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster
Packaging: 500mg
Price: $1320
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 49055
Product name: 2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster
Packaging: 500mg
Price: $2200
Updated: 2021/12/16

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(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Chemical Properties,Usage,Production

Uses

2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylic Acid Ethyl Ester is used in the preparation Gatifloxacin (G250000) and key intermediates for the synthesis third-generation fluoroquinolone antibiotics.

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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112811-70-8, (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATERelated Search:

2,4,5-Trifluoro-3-methoxybenzoyl chloride Cyclopropylamine Moxifloxacin Ethyl Ester 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid ethyl ester 6-Benzyl-5,7-dihydro-5,7-dioxopyrrolo[3,4-b]pyridine Moxifloxacin Impurity 46 1-Cyclopropyl-7-8-difluoro-6-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester (4aS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine trans-octahydro-1H-pyrrolo[3,4-b]pyridine 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid cis-Octahydropyrrolo[3,4-b]pyridine N-Methyl Moxifloxacin CIS-OCTAHYDROPYRROLO[3,4-B]PYRIDINE Moxifloxacin Impurity 29 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-hydroxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid Moxifloxacin 1-Cyclopropyl-8-ethoxy-6-fluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Moxifloxacin hydrochloride

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

2-(2,4,5-Trifluoro-3-Methoxybenzoyl)-3-cyclopropylaMinoacrylic Acid Ethyl Ester

Ethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylate

(E)-ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate

Moxifloxacin Impurity Ⅷ

3-(cyclopropylamino)-2-[oxo-(2,4,5-trifluoro-3-methoxyphenyl)methyl]-2-propenoic acid ethyl ester

Moxifloxacin Intermediate Impurity 2 Control

Moxifloxacin Intermediate Impurity 2

Benzenepropanoic acid, α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-3-methoxy-β-oxo-, ethyl ester

ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate

Benzenepropanoic acid, α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-3-methoxy-β-oxo-, ethyl ester (9CI, ACI)

Azilsartan medoxomil impurity266

Ethyl(Z)-3-(Cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate

112811-70-8

Amines

Aromatics

Intermediates