ChemicalBook > CAS DataBase List > (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE

Product Name
(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE
CAS No.
112811-70-8
Chemical Name
(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE
Synonyms
Moxifloxacin Impurity Ⅷ;Azilsartan medoxomil impurity266;Moxifloxacin Intermediate Impurity 2;Moxifloxacin Intermediate Impurity 2 Control;Ethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylate;ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE;(E)-ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate;2-(2,4,5-Trifluoro-3-Methoxybenzoyl)-3-cyclopropylaMinoacrylic Acid Ethyl Ester;3-(cyclopropylamino)-2-[oxo-(2,4,5-trifluoro-3-methoxyphenyl)methyl]-2-propenoic acid ethyl ester
CBNumber
CB52468409
Molecular Formula
C16H16F3NO4
Formula Weight
343.3
MOL File
112811-70-8.mol
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(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Property

Boiling point:
463.2±45.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
2.70±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T790730
Product name
2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster
Packaging
500mg
Price
$1320
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
49055
Product name
2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylicAcidEthylEster
Packaging
500mg
Price
$2200
Updated
2021/12/16
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(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Chemical Properties,Usage,Production

Uses

2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylic Acid Ethyl Ester is used in the preparation Gatifloxacin (G250000) and key intermediates for the synthesis third-generation fluoroquinolone antibiotics.

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Suppliers

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112811-70-8, (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATERelated Search:

2,4,5-Trifluoro-3-methoxybenzoyl chloride Cyclopropylamine Moxifloxacin Ethyl Ester 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid ethyl ester 6-Benzyl-5,7-dihydro-5,7-dioxopyrrolo[3,4-b]pyridine Moxifloxacin Impurity 46 1-Cyclopropyl-7-8-difluoro-6-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester (4aS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine trans-octahydro-1H-pyrrolo[3,4-b]pyridine 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid cis-Octahydropyrrolo[3,4-b]pyridine N-Methyl Moxifloxacin CIS-OCTAHYDROPYRROLO[3,4-B]PYRIDINE Moxifloxacin Impurity 29 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-hydroxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid Moxifloxacin 1-Cyclopropyl-8-ethoxy-6-fluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Moxifloxacin hydrochloride

  • (Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE
  • 2-(2,4,5-Trifluoro-3-Methoxybenzoyl)-3-cyclopropylaMinoacrylic Acid Ethyl Ester
  • Ethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylate
  • (E)-ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate
  • Moxifloxacin Impurity Ⅷ
  • 3-(cyclopropylamino)-2-[oxo-(2,4,5-trifluoro-3-methoxyphenyl)methyl]-2-propenoic acid ethyl ester
  • Moxifloxacin Intermediate Impurity 2 Control
  • Moxifloxacin Intermediate Impurity 2
  • Benzenepropanoic acid, α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-3-methoxy-β-oxo-, ethyl ester
  • ethyl 3-(cyclopropylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate
  • Benzenepropanoic acid, α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-3-methoxy-β-oxo-, ethyl ester (9CI, ACI)
  • Azilsartan medoxomil impurity266
  • 112811-70-8
  • Amines
  • Aromatics
  • Intermediates