7-Amino-5-fluoroindolin-2-one
- Product Name
- 7-Amino-5-fluoroindolin-2-one
- CAS No.
- 945381-62-4
- Chemical Name
- 7-Amino-5-fluoroindolin-2-one
- Synonyms
- 7-AMino-5-fluoro-2-oxyindole;7-Amino-5-fluoroindolin-2-one;7-amino-5-fluoro-1,3-dihydro-indol-2-one;7-aMino-5-fluoro-1,3-dihydro-2H-Indol-2-one;2H-Indol-2-one, 7-amino-5-fluoro-1,3-dihydro-
- CBNumber
- CB52471544
- Molecular Formula
- C8H7FN2O
- Formula Weight
- 166.15
- MOL File
- 945381-62-4.mol
7-Amino-5-fluoroindolin-2-one Property
- Boiling point:
- 383.5±42.0 °C(Predicted)
- Density
- 1.413±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 12.52±0.20(Predicted)
- Appearance
- Brown to reddish brown Solid
Safety
- HS Code
- 2933998090
N-Bromosuccinimide Price
- Product number
- A636710
- Product name
- 7-Amino-5-fluoro-1,3-dihydro-2H-indol-2-one
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC201382
- Product name
- 7-Amino-5-fluoroindolin-2-one
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $67
- Updated
- 2021/12/16
- Product number
- FA104789
- Product name
- 7-Amino-5-fluoro-1,3-dihydroindol-2-one
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FA104789
- Product name
- 7-Amino-5-fluoro-1,3-dihydroindol-2-one
- Packaging
- 25mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- PC201382
- Product name
- 7-Amino-5-fluoroindolin-2-one
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $135
- Updated
- 2021/12/16
7-Amino-5-fluoroindolin-2-one Chemical Properties,Usage,Production
Synthesis
1082990-05-3
945381-62-4
Step 2: 5-Fluoro-7-nitro-1,3-dihydroindol-2-one (20a, 4.0 g, 20 mmol) was dissolved in 200 mL of acetic acid and palladium/activated carbon catalyst (1.0 g, 5%) was added with stirring at room temperature. The reaction mixture was stirred continuously under hydrogen atmosphere. The reaction progress was monitored by thin layer chromatography (TLC) and stopped when the feedstock completely disappeared. The reaction mixture was filtered to remove the catalyst and the filtrate was concentrated under reduced pressure to afford the white solid product 7-amino-5-fluoro-1,3-dihydroindol-2-one (20b, 3.2 g, 97.5% yield).
References
[1] Patent: US2010/75952, 2010, A1. Location in patent: Page/Page column 56
[2] Patent: EP2157093, 2010, A1. Location in patent: Page/Page column 51
7-Amino-5-fluoroindolin-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
7-Amino-5-fluoroindolin-2-one Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58