ChemicalBook > CAS DataBase List > N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide

Product Name
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
CAS No.
503610-43-3
Chemical Name
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
Synonyms
Rosuvastatin EP Imp D;Rsosuvastatin Lactone;Rosuvastatin calcium-5;Rosuvastatin-5S-lactone;Rosuvastatin Lactone-d3;Rosuvastatin-5R-lactone;Rosuvastatin Impurity D;Rosuvastatin EP Impurity D;Rosuvastatin lactone, >=98%;(3R,5R)-Rosuvastatin Lactone
CBNumber
CB52484896
Molecular Formula
C22H26FN3O5S
Formula Weight
463.52
MOL File
503610-43-3.mol
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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Property

Melting point:
131 °C
Boiling point:
695.0±65.0 °C(Predicted)
Density 
1.387
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.22±0.40(Predicted)
form 
Solid
color 
White to Off-White
Major Application
pharmaceutical
InChIKey
SOEGVMSNJOCVHT-VEUZHWNKSA-N
SMILES
Fc1ccc(cc1)c2nc(nc(c2\C=C\[C@H]3OC(=O)C[C@@H](C3)O)C(C)C)N([S](=O)(=O)C)C
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
Hazard Classifications
STOT RE 2 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
R700550
Product name
RosuvastatinLactone
Packaging
5mg
Price
$70
Updated
2021/12/16
TRC
Product number
R700550
Product name
RosuvastatinLactone
Packaging
10mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FR27761
Product name
Rosuvastatin lactone
Packaging
5mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FR27761
Product name
Rosuvastatin lactone
Packaging
10mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FR27761
Product name
Rosuvastatin lactone
Packaging
25mg
Price
$150
Updated
2021/12/16
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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

An isomer of Rosuvastatin Lactone (R700500); intermediate in the production of Rosuvastatin (R700500) derivatives.

Uses

Rosuvastatin Lactone (Rosuvastatin EP Impurity D) is an intermediate in the production of Rosuvastatin (R700500) derivatives.

Definition

ChEBI: Rosuvastatin lactone is a member of pyrimidines.

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Suppliers

Canada 2 China 135 India 7 United Kingdom 1 United States 10 Global 155
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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XiaoGan ShenYuan ChemPharm co,ltd
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15527621225
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1791901229@qq.com
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China
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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China
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-4000505016 13380397412
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0755 28094224
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3001272453@qq.com
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China
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-83725681-603
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+86 755 28094224
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China
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TargetMol Chemicals Inc.
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021-021-33632979 15002134094
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021-33632979
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marketing@targetmol.com
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China
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Cato Research Chemicals Inc.
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020-81960175
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+1-541-2553641
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min.he@cato-chem.com
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China
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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+86-21-61629029
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product02@bidepharm.com
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China
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Quality Control Solutions Ltd.
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66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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China
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View Lastest Price from N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide manufacturers

Career Henan Chemical Co
Product
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide 503610-43-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-16

503610-43-3, N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamideRelated Search:

Rosuvastatin EP Impurity E (Calcium Salt) Pitavastatin Impurity 8 Rosuvastatin Impurity 14 (3R,5R)-Rosuvastatin N-DESMETHYL ROSUVASTATIN-D3 (3S,5R)-Rosuvastatin Methyl Ester Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester) Rosuvastatin Anhydro Lactone Rosuvastatin IsoaMy Ester Rosuvastatin EP impurity A (3S,5R)-Rosuvastatin Rosuvastatin methyl ester tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol 3-Oxo Rosuvastatin SodiuM Salt Rosuvastatin ethyl ester Rosuvastatin EP impurity H Rosuvastatin

  • Rosuvastatin (5S)-Lactone/N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonam
  • Rosuvastatin Impurity 1/Rosuvastatin EP Impurity D/Rosuvastatin (3R,5S)-Lactone
  • Rosuvastatin calcium-5
  • Rosuvastatin EP Imp D
  • Rosuvastatin Impurity 6(Rosuvastatin EP Impurity D)
  • Rosuvastatin Lactone EP impurity D
  • Rosuvastatin Calcium EP Impurity D
  • N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
  • Rosuvastatin-5S-lactone
  • (3R,5R)-Rosuvastatin Lactone
  • Rosuvastatin Lactone-d3
  • N-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-5-[(1E)-2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyriMidinyl]-N-Methyl-MethanesulfonaMide
  • Rosuvastatin-5R-lactone
  • N-(4-(4-fluorophenyl)-5-((E)-2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)vinyl)-6-isopropylpyriMidin-2-yl)-N-MethylMethanesulfonaMide
  • Rosuvastatin lactone, >=98%
  • Rosuvastatin EP Impurity D
  • 1-[4-[2-HYDROXY-3-[(1-METHYL-ETHYL)AMINO]PROPOXY]-1H-INDOL-1-YL]-3-[(1-METHYLETHYL)AMINO]PROPAN-2-OL
  • Rsosuvastatin Lactone
  • Rosuvastatin calcium impurity D
  • Rosuvastatin (5S)-Lactone/N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide/N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S ,4R )-4-hydroxy-6-oxotetrahydro-2H -pyran-2- yl]vinyl}-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
  • Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-
  • Rosuvastatin EP Impurity D (Rosuvastatin (3R,5S)-Lactone)
  • Rosuvastatin Impurity-D(lactone)
  • Rosuvastatin LactoneQ: What is Rosuvastatin Lactone Q: What is the CAS Number of Rosuvastatin Lactone Q: What is the storage condition of Rosuvastatin Lactone Q: What are the applications of Rosuvastatin Lactone
  • rahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
  • Rosuvastatin Lactone I (Rosuvastatin 5S Lactone) (EP Impurity D)
  • 3-Benzofuranpropanenitrile,β-oxo-
  • Benzenesulfonylchloride,4-methoxy-2-methyl-5-(2-methylethyl)-
  • Rosuvastatin EP Impurity D (Calcium Salt)
  • Rosuvastatin EP Impurity D N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)- tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2- pyrimidinyl]-N-methyl-methanesulfonamide
  • N-[4-(4-Fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethenyl]-6-(1-methyl
  • Rosuvastatin Impurity D
  • rosuvastatin lactone, 97%min
  • N-[4-(4-Fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethenyl]-6-(1-methylethyl)pyrimidin-2-yl]-N-methylmethanesulfonamide (Rosuvastatin Lactone)
  • 503610-43-3
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Isotopically Labeled Pharmaceutical Reference Standard
  • Pharmaceuticals
  • Sulfur & Selenium Compounds