ChemicalBook > CAS DataBase List > (3S,5R)-Rosuvastatin

(3S,5R)-Rosuvastatin

Product Name
(3S,5R)-Rosuvastatin
CAS No.
1242184-42-4
Chemical Name
(3S,5R)-Rosuvastatin
Synonyms
5R)-Rosuvastatin;(3S,5R)-Rosuvastatin;Rosuvastatin calcium-8;Rosuvastatin Impurity G;(3S,5R,6E)-Rosuvastatin;Rosuvastatin EP Impurity G;*Buprenorphine Impurity 17;Rosuvastatin impurity G CRS;Rosuvastatin Acid Enantiomer;Rosuvastatin EP Imp G (acid)
CBNumber
CB52706297
Molecular Formula
C22H28FN3O6S
Formula Weight
481.54
MOL File
1242184-42-4.mol
More
Less

(3S,5R)-Rosuvastatin Property

Boiling point:
745.6±70.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
solubility 
soluble in Methanol, Water
pka
4.25±0.10(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0028000
Product name
ROSUVASTATIN RC D
Purity
95.00%
Packaging
5MG
Price
$450.2
Updated
2021/12/16
More
Less

(3S,5R)-Rosuvastatin Chemical Properties,Usage,Production

Description

Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.

Uses

(3S,5R,6E)-Rosuvastatin is an isomer of Rosuvastatin(R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor.

Biological Activity

(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

(3S,5R)-Rosuvastatin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(3S,5R)-Rosuvastatin Suppliers

Yangzhou Changhua Biotechnology Co., Ltd.
Tel
13815846020; 13815846020
Email
438399391@qq.com
Country
China
ProdList
861
Advantage
58
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
4937
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2965
Advantage
58
Tonichem Pharmaceutical Technology Co., Ltd.
Tel
+86 (0752) 222-7171, +86 15815821171
Fax
+86 (0752) 222-6171
Country
China
ProdList
1120
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai CR Corporation Limited
Tel
021-80270511; 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
10044
Advantage
58
More
Less

View Lastest Price from (3S,5R)-Rosuvastatin manufacturers

Guangzhou PI PI BIOTECH INC
Product
Rosuvastatin Calcium Impurity G 1242184-42-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-06-12

1242184-42-4, (3S,5R)-RosuvastatinRelated Search:


  • (3S,5R)-Rosuvastatin
  • (3s,5r,6e)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
  • Rosuvastatin Calcium EP Impurity G (Calcium Salt)
  • Rosuvastatin EP impurity G(3S5R)
  • Rosuvastatin Impurity G
  • Rosuvastatin EP Imp G (acid)
  • Rosuvastatin calcium-8
  • 3S,5R-Rosuvastatin calcium salt
  • Rosuvastatin EP Impurity G
  • Rosuvastatin (3S,5R) Enantiomer (as diisopropylamine salt)
  • (3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
  • Rosuvastatin EP Impurity G (Calcium Salt)
  • Rosuvastatin impurity G CRS
  • (3S,5R)-Rosuvastatin Sodium Salt
  • 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3S,5R,6E)-
  • Rosuvastatin (3S,5R) enantiomer
  • (3S,5R,6E)-Rosuvastatin
  • (3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid, calcium salt (2:1)
  • Rosuvastatin EP Impurity G/ Rosuvastatin Related Compund D (Rosuvastatin Calcium Enantiomer/ enti-Rosuvastatin/ Rosuvastatin (3S,5R)-Isomer)
  • Rosuvastatin impurity G (Y0001722)Q: What is Rosuvastatin impurity G (Y0001722) Q: What is the CAS Number of Rosuvastatin impurity G (Y0001722)
  • (3S,5R)-Rosuvastatin CalciumQ: What is (3S,5R)-Rosuvastatin Calcium Q: What is the CAS Number of (3S,5R)-Rosuvastatin Calcium Q: What is the storage condition of (3S,5R)-Rosuvastatin Calcium Q: What are the applications of (3S,5R)-Rosuvastatin Calcium
  • Rosuvastatin Acid Enantiomer
  • 5R)-Rosuvastatin
  • Rosuvastatin EP Impurity G / Rosuvastatin Related Compound D / 3S, 5R Rosuvastatin
  • (3S,5R) Rosuvastatin,(3S,5R)Rosuvastatin
  • ((3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl sulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II)(Rosuvastatin EP Impurity G)
  • Rosuvastatin Impurity 11 Monomer(Rosuvastatin EP Impurity G Monomer)
  • *Buprenorphine Impurity 17
  • (3S,5R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxy-6(E)-heptenoic acid calcium salt
  • 1242184-42-4