(3S,5R)-Rosuvastatin

Product Name: (3S,5R)-Rosuvastatin
CAS No.: 1242184-42-4
Chemical Name: (3S,5R)-Rosuvastatin
Synonyms: 5R)-Rosuvastatin;(3S,5R)-Rosuvastatin;Rosuvastatin calcium-8;Rosuvastatin Impurity G;(3S,5R,6E)-Rosuvastatin;Rosuvastatin EP Impurity G;*Buprenorphine Impurity 17;Rosuvastatin impurity G CRS;Rosuvastatin Acid Enantiomer;Rosuvastatin EP Imp G (acid)
CBNumber: CB52706297
Molecular Formula: C22H28FN3O6S
Formula Weight: 481.54
MOL File: 1242184-42-4.mol

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(3S,5R)-Rosuvastatin Property

Boiling point:: 745.6±70.0 °C(Predicted)
Density: 1.368±0.06 g/cm3(Predicted)
solubility: soluble in Methanol, Water
pka: 4.25±0.10(Predicted)
form: Solid
color: Off-White to Pale Yellow
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0028000
Product name: ROSUVASTATIN RC D
Purity: 95.00%
Packaging: 5MG
Price: $450.2
Updated: 2021/12/16

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(3S,5R)-Rosuvastatin Chemical Properties,Usage,Production

Description

Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.

Uses

(3S,5R,6E)-Rosuvastatin is an isomer of Rosuvastatin(R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor.

Biological Activity

(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

(3S,5R)-Rosuvastatin Preparation Products And Raw materials

Raw materials

Preparation Products

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(3S,5R)-Rosuvastatin Suppliers

Canada 1 China 60 India 4 United States 7 Global 72

Yangzhou Changhua Biotechnology Co., Ltd.

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BOC Sciences

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Beijing Comparison Pharmaceutical Technology Co., Ltd

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Country: China
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Finetech Industry Limited

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Shanghai Kewel Chemical Co., Ltd.

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Nanjing XiZe Biotechnology CO., Ltd.

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Artis Biotech Co. Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
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View Lastest Price from (3S,5R)-Rosuvastatin manufacturers

Guangzhou PI PI BIOTECH INC

Product: Rosuvastatin Calcium Impurity G 1242184-42-4
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2020-06-12

1242184-42-4, (3S,5R)-RosuvastatinRelated Search:

Rosuvastatin EP Impurity E (Calcium Salt) Pitavastatin Impurity 8 Rosuvastatin Impurity 14 (3R,5R)-Rosuvastatin N-DESMETHYL ROSUVASTATIN-D3 Rosuvastatin (3S,5R)-Rosuvastatin Methyl Ester Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester) Rosuvastatin Anhydro Lactone Rosuvastatin IsoaMy Ester Rosuvastatin EP impurity A N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Rosuvastatin methyl ester tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol 3-Oxo Rosuvastatin SodiuM Salt Rosuvastatin ethyl ester Rosuvastatin EP impurity H

(3S,5R)-Rosuvastatin

(3s,5r,6e)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid

Rosuvastatin Calcium EP Impurity G (Calcium Salt)

Rosuvastatin EP impurity G(3S5R)

Rosuvastatin Impurity G

Rosuvastatin EP Imp G (acid)

Rosuvastatin calcium-8

3S,5R-Rosuvastatin calcium salt

Rosuvastatin EP Impurity G

Rosuvastatin (3S,5R) Enantiomer (as diisopropylamine salt)

(3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid

Rosuvastatin EP Impurity G (Calcium Salt)

Rosuvastatin impurity G CRS

(3S,5R)-Rosuvastatin Sodium Salt

6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3S,5R,6E)-

Rosuvastatin (3S,5R) enantiomer

(3S,5R,6E)-Rosuvastatin

(3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid, calcium salt (2:1)

Rosuvastatin EP Impurity G/ Rosuvastatin Related Compund D (Rosuvastatin Calcium Enantiomer/ enti-Rosuvastatin/ Rosuvastatin (3S,5R)-Isomer)

Rosuvastatin impurity G (Y0001722)Q: What is Rosuvastatin impurity G (Y0001722) Q: What is the CAS Number of Rosuvastatin impurity G (Y0001722)

(3S,5R)-Rosuvastatin CalciumQ: What is (3S,5R)-Rosuvastatin Calcium Q: What is the CAS Number of (3S,5R)-Rosuvastatin Calcium Q: What is the storage condition of (3S,5R)-Rosuvastatin Calcium Q: What are the applications of (3S,5R)-Rosuvastatin Calcium

Rosuvastatin Acid Enantiomer

5R)-Rosuvastatin

Rosuvastatin EP Impurity G / Rosuvastatin Related Compound D / 3S, 5R Rosuvastatin

(3S,5R) Rosuvastatin,(3S,5R)Rosuvastatin

((3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl sulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II)（Rosuvastatin EP Impurity G）

Rosuvastatin Impurity 11 Monomer(Rosuvastatin EP Impurity G Monomer)

*Buprenorphine Impurity 17

(3S,5R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxy-6(E)-heptenoic acid calcium salt

1242184-42-4