(3S,5R)-Rosuvastatin
- Product Name
- (3S,5R)-Rosuvastatin
- CAS No.
- 1242184-42-4
- Chemical Name
- (3S,5R)-Rosuvastatin
- Synonyms
- 5R)-Rosuvastatin;(3S,5R)-Rosuvastatin;Rosuvastatin calcium-8;Rosuvastatin Impurity G;(3S,5R,6E)-Rosuvastatin;Rosuvastatin EP Impurity G;*Buprenorphine Impurity 17;Rosuvastatin impurity G CRS;Rosuvastatin Acid Enantiomer;Rosuvastatin EP Imp G (acid)
- CBNumber
- CB52706297
- Molecular Formula
- C22H28FN3O6S
- Formula Weight
- 481.54
- MOL File
- 1242184-42-4.mol
(3S,5R)-Rosuvastatin Property
- Boiling point:
- 745.6±70.0 °C(Predicted)
- Density
- 1.368±0.06 g/cm3(Predicted)
- solubility
- soluble in Methanol, Water
- pka
- 4.25±0.10(Predicted)
- form
- Solid
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0028000
- Product name
- ROSUVASTATIN RC D
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $450.2
- Updated
- 2021/12/16
(3S,5R)-Rosuvastatin Chemical Properties,Usage,Production
Description
Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Uses
(3S,5R,6E)-Rosuvastatin is an isomer of Rosuvastatin(R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor.
Biological Activity
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
(3S,5R)-Rosuvastatin Preparation Products And Raw materials
Raw materials
Preparation Products
(3S,5R)-Rosuvastatin Suppliers
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View Lastest Price from (3S,5R)-Rosuvastatin manufacturers
- Product
- Rosuvastatin Calcium Impurity G 1242184-42-4
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 90%+
- Supply Ability
- 10g
- Release date
- 2020-06-12