tert-butyl azetidin-3-ylmethyl(methyl)carbamate

Product Name: tert-butyl azetidin-3-ylmethyl(methyl)carbamate
CAS No.: 1053655-53-0
Chemical Name: tert-butyl azetidin-3-ylmethyl(methyl)carbamate
Synonyms: 3-(N-Boc-Methylaminomethy...;3-[Boc(methyl)aminomethyl]azetidine,95%;3-[Boc(Methyl)aMinoMethyl]azetidine, 95%;N-Boc-1-(3-azetidinyl)-N-methylmethanamine;tert-butyl azetidin-3-ylmethyl(methyl)carbamate;tert-butyl N-(azetidin-3-ylmethyl)-N-methylcarbamate;1,1-Dimethylethyl N-(3-azetidinylmethyl)-N-methylcarbamate;N-(3-Azetidinylmethyl)-N-methylcarbamic acid tert-butyl ester;N-(3-azetidinylMethyl)-n-Methyl-carbaMic acid 1,1-diMethylethyl ester;Carbamic acid, N-(3-azetidinylmethyl)-N-methyl-, 1,1-dimethylethyl ester
CBNumber: CB52490295
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 1053655-53-0.mol

More

Less

tert-butyl azetidin-3-ylmethyl(methyl)carbamate Property

Boiling point:: 267℃
Density: 1.012
Flash point:: 116℃
storage temp.: 2-8°C(protect from light)
pka: 10.86±0.40(Predicted)

More

Less

Safety

HazardClass: IRRITANT

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: H60310
Product name: 3-[Boc(methyl)aminomethyl]azetidine, 95%
Packaging: 250mg
Price: $214
Updated: 2023/06/20

Alfa Aesar

Product number: H60310
Product name: 3-[Boc(methyl)aminomethyl]azetidine, 95%
Packaging: 1g
Price: $612
Updated: 2023/06/20

TRC

Product number: B789533
Product name: tert-ButylAzetidin-3-ylmethyl(methyl)carbamate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 059926
Product name: 3-(N-Boc-Methylaminomethyl)azetidine
Purity: 95%
Packaging: 1g
Price: $612
Updated: 2021/12/16

Matrix Scientific

Product number: 059926
Product name: 3-(N-Boc-Methylaminomethyl)azetidine
Purity: 95%
Packaging: 500mg
Price: $475
Updated: 2021/12/16

More

Less

tert-butyl azetidin-3-ylmethyl(methyl)carbamate Chemical Properties,Usage,Production

Uses

Tert-butyl azetidin-3-ylmethyl(methyl)carbamate is an important organic reagent that can be used as a building block for the synthesis of tert-butyl ((1-((4-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)azetidin-3-yl)methyl)(methyl)carbamate which is an important intermediate of a selective small-molecule PLK inhibitors useful in the treatment of cell proliferative disorders.

Synthesis

A solution of tert-butyl ((1-benzhydrylazetidin-3-yl)methyl)carbamate (6.18 g, 17.53 mmol) in 50 mL of MeOH and 15 mL of EtOAc was purged with argon. Pd/C (10%, 50% in water) (929 mg) was added and the mixture was then purged again with argon and stirred in an H2 atmosphere for 18 h. The reaction was filtered through Ceitte and the filter was washed with EtOAc and MeOH, The resulting solvent was evaporated to dryness, providing 5.66 g of a mixture of tert-butyl azetidin-3-ylmethyl(methyl)carbamate together with one equivalent of diphenylmethane. The pure product tert-butyl azetidin-3-ylmethyl(methyl)carbamate was obtained after further purification.

tert-butyl azetidin-3-ylmethyl(methyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

tert-butyl azetidin-3-ylmethyl(methyl)carbamate Suppliers

China 34 Germany 1 India 1 United States 7 Global 43

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7906
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19179
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Shanghai Sheepchem Co., Ltd.

Tel: +86 (21) 6715-7650
Fax: +86 (21) 6715-7651
Email: sheepchem@163.com
Country: China
ProdList: 994
Advantage: 60

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9894
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Porse Fine Chemical Co.,LTD

Tel: 20-66003216 18666003216
Fax: +86-20-28069063
Email: info@porsefinechemical.com
Country: China
ProdList: 2353
Advantage: 62

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 18019252918
Fax: QQ:1454668768
Email: sale@amkchem.com
Country: China
ProdList: 15297
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 9998
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15084
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9990
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30238
Advantage: 58

SIMAGCHEM CORP

Tel: +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17365
Advantage: 58

Henan Pumei Jihua Pharmaceutical Technology Co., Ltd.

Tel: 037188900765 18037465274
Fax: QQ3430974218
Email: enyawanglei@sina.cn
Country: China
ProdList: 13747
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 11725
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 4008210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 54987
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44806
Advantage: 58

Mainchem Co., Ltd.

Tel: --
Fax: --
Email: sarah@mainchem.com
Country: China
ProdList: 6567
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44458
Advantage: 58

Anqing Rong Chuang Biological Technology Co., Ltd.

Tel: 15001988657
Email: 1367753897@qq.com
Country: China
ProdList: 1003
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Email: sales@peking-pharmacy.com
Country: China
ProdList: 10741
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-02759101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 6009
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43340
Advantage: 58

Shanghai Boc Chemical Co., Ltd.

Tel: 021-34975602; +8618721111801
Email: shangli@bocchem.com
Country: China
ProdList: 138
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: --
Fax: --
Email: sales@sunwaypharm.com
Country: China
ProdList: 6536
Advantage: 58

Edengene Chemical Limited

Tel: --
Fax: --
Email: info@edengenechem.com
Country: China
ProdList: 1491
Advantage: 30

1053655-53-0, tert-butyl azetidin-3-ylmethyl(methyl)carbamateRelated Search:

tert-butyl azetidin-3-ylmethyl(methyl)carbamate

3-(N-Boc-Methylaminomethy...

3-[Boc(Methyl)aMinoMethyl]azetidine, 95%

N-(3-Azetidinylmethyl)-N-methylcarbamic acid tert-butyl ester

N-(3-azetidinylMethyl)-n-Methyl-carbaMic acid 1,1-diMethylethyl ester

tert-butyl N-(azetidin-3-ylmethyl)-N-methylcarbamate

Carbamic acid, N-(3-azetidinylmethyl)-N-methyl-, 1,1-dimethylethyl ester

3-[Boc(methyl)aminomethyl]azetidine,95%

N-Boc-1-(3-azetidinyl)-N-methylmethanamine

1,1-Dimethylethyl N-(3-azetidinylmethyl)-N-methylcarbamate

1053655-53-0