2-ETHYNYLBENZALDEHYDE
- Product Name
- 2-ETHYNYLBENZALDEHYDE
- CAS No.
- 38846-64-9
- Chemical Name
- 2-ETHYNYLBENZALDEHYDE
- Synonyms
- 2-ETHYNYLBENZALDEHYDE;2-Formylphenylacetylene;Benzaldehyde, 2-ethynyl-;2-Ethynylbenzaldehyde97%;2-Ethynylbenzaldehyde 97%;2-ETHYLNYLBENZALDEHYDE, 97%;Benzaldehyde, 2-ethynyl- (9CI)
- CBNumber
- CB5249664
- Molecular Formula
- C9H6O
- Formula Weight
- 130.14
- MOL File
- 38846-64-9.mol
2-ETHYNYLBENZALDEHYDE Property
- Melting point:
- 64-67 °C (lit.)
- Boiling point:
- 115 °C(Press: 12 Torr)
- Density
- 1.07±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- color
- Light yellow to light brown
- InChIKey
- ZEDSAJWVTKUHHK-UHFFFAOYSA-N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 590630
- Product name
- 2-Ethynylbenzaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $64.5
- Updated
- 2025/07/31
- Product number
- 590630
- Product name
- 2-Ethynylbenzaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $224
- Updated
- 2025/07/31
- Product number
- E1420
- Product name
- 2-Ethynylbenzaldehyde
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $136
- Updated
- 2025/07/31
- Product number
- E932173
- Product name
- 2-Ethynylbenzaldehyde
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- X5270
- Product name
- 2-Ethynylbenzaldehyde
- Packaging
- 1g
- Price
- $47
- Updated
- 2021/12/16
2-ETHYNYLBENZALDEHYDE Chemical Properties,Usage,Production
Uses
2-Ethynylbenzaldehyde may be used in the synthesis of the following:
- iodoisoquinoline-fused benzimidazoles obtained via tandem iodocyclization of 2-ethynylbenzaldehyde with o-benzenediamine and iodine in the presence of copper(I)iodide
- N-[(7,7a-dihydroisoquinolino[2,1-a]perimidin-13-yl)methyl]-N-isopropylpropan-2-amine obtained via a multi-step process
- 2-[(2-bromophenyl)ethynyl]benzaldehyde
- 2-[(2-bromo-5-fluorophenyl)ethynyl]benzaldehyde
- 2-[(2-bromo-5-methylphenyl)ethynyl]benzaldehyde
- 2-(phenylethynyl)benzaldehyde
- 2-[(4-methylphenyl)ethynyl]benzaldehyde
Synthesis
77123-58-1
38846-64-9
General procedure for the synthesis of 2-ethynylbenzaldehyde from 2-[(trimethylmethylsilyl)ethynyl]benzaldehyde: 2-[(trimethylmethylsilyl)ethynyl]benzaldehyde (1 mmol), an inorganic base (potassium tert-butanol, sodium tert-butanol, potassium hydroxide, sodium hydroxide, or potassium trimethylmethylsilyl, sodium trimethylmethylsilyl, 0.05 mmol), and 2 mL of DMA or DMSO solvent were added to a 10mL sealed tube. The mixture was placed in an oil bath at 60 °C and the reaction was stirred for 12 h. The progress of the reaction was monitored by TLC. Upon completion of the reaction, equal amounts of homotrimethylbenzene or n-undecane were added as an internal standard for the crude product, and the exact yield of the product was determined by GC and GC-MS analysis. According to the results of GC and GC-MS analyses, when DMSO was used as the reaction solvent and potassium tert-butanol, sodium tert-butanol, potassium hydroxide, sodium hydroxide, or potassium trimethylmethylsilyl, sodium trimethylmethylsilyl were used as catalysts, the yields of the products were 44%, 47%, 49%, 50%, 77%, and 70% respectively. When DMA was used as the reaction solvent with the same inorganic base as the catalyst, the yields of the products were 40%, 42%, 42%, 40%, 61%, 59%, respectively.
References
[1] Synthesis, 2010, # 14, p. 2367 - 2378
[2] European Journal of Organic Chemistry, 2017, vol. 2017, # 11, p. 1425 - 1433
[3] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987, p. 2321 - 2332
[4] Advanced Synthesis and Catalysis, 2011, vol. 353, # 2-3, p. 392 - 400
[5] Journal of the American Chemical Society, 2015, vol. 137, # 9, p. 3233 - 3236
2-ETHYNYLBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-ETHYNYLBENZALDEHYDE manufacturers
- Product
- 2-ETHYNYLBENZALDEHYDE 38846-64-9
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1-1000kg
- Release date
- 2019-12-25