2-oxa-6-azaspiro[3.4]octane

Product Name: 2-oxa-6-azaspiro[3.4]octane
CAS No.: 220290-68-6
Chemical Name: 2-oxa-6-azaspiro[3.4]octane
Synonyms: 2-oxa-7-azaspiro[3.4]octane;2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-oxa-6-azaspiro[3.4]octane, hemioxalate salt
CBNumber: CB52506037
Molecular Formula: C6H11NO
Formula Weight: 113.16
MOL File: 220290-68-6.mol

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2-oxa-6-azaspiro[3.4]octane Property

Boiling point:: 187℃
Density: 1.08
Flash point:: 63°(145°F)
storage temp.: 2-8°C(protect from light)
pka: 10.55±0.20(Predicted)
Water Solubility: Soluble in water.
InChI: InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2
InChIKey: ZHAIMJRKJKQNQI-UHFFFAOYSA-N
SMILES: C1C2(CCNC2)CO1

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Safety

HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: H57579
Product name: 2-Oxa-6-azaspiro[3.4]octane, 95%
Packaging: 250mg
Price: $324.65
Updated: 2024/03/01

Alfa Aesar

Product number: H57579
Product name: 2-Oxa-6-azaspiro[3.4]octane, 95%
Packaging: 500mg
Price: $592.65
Updated: 2024/03/01

Usbiological

Product number: 285953
Product name: 2-Oxa-6-azaspiro[3.4]octane
Packaging: 25mg
Price: $359
Updated: 2021/12/16

TRC

Product number: O990125
Product name: 2-Oxa-6-Azaspiro[3.4]Octane
Packaging: 10mg
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H31-1-10
Product name: 2-Oxa-6-azaspiro[3.4]octane
Packaging: 250mg
Price: $295
Updated: 2021/12/16

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2-oxa-6-azaspiro[3.4]octane Chemical Properties,Usage,Production

Uses

2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.

Application

2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.

Synthesis

Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.

2-oxa-6-azaspiro[3.4]octane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-oxa-6-azaspiro[3.4]octane Suppliers

China 72 India 2 United Kingdom 2 United States 8 Global 84

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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SynAsst Chemical.

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View Lastest Price from 2-oxa-6-azaspiro[3.4]octane manufacturers

Career Henan Chemical Co

Product: 2-oxa-6-azaspiro[3.4]octane 220290-68-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%-99.9%
Supply Ability: 100kg
Release date: 2020-01-10

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220290-68-6