ChemicalBook > CAS DataBase List > Tebipenem

Tebipenem

Product Name
Tebipenem
CAS No.
161715-21-5
Chemical Name
Tebipenem
Synonyms
LJC11036;LJC-11036;Tebipenem;LJC 11036;Tibipronam;Tebipenem USP/EP/BP;Tebipenem Impurity 5;Tibipenem intermediate 2;inhibit,LJC11036,Bacterial,LJC-11036,Antibiotic,Inhibitor;(4R,5S,6S)-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CBNumber
CB52534496
Molecular Formula
C16H21N3O4S2
Formula Weight
383.49
MOL File
161715-21-5.mol
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Tebipenem Property

Boiling point:
624.5±65.0 °C(Predicted)
Density 
1.75
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
insoluble in EtOH; ≥19.15 mg/mL in H2O with gentle warming; ≥24.9 mg/mL in DMSO
form 
solid
pka
4.29±0.60(Predicted)
color 
White to khaki
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3203
Product name
Tebipenem
Purity
≥98% (HPLC)
Packaging
10MG
Price
$81
Updated
2024/03/01
Sigma-Aldrich
Product number
SML3203
Product name
Tebipenem
Purity
≥98% (HPLC)
Packaging
50MG
Price
$261
Updated
2024/03/01
ChemScene
Product number
CS-3444
Product name
Tebipenem
Purity
>98.0%
Packaging
10mg
Price
$336
Updated
2021/12/16
ApexBio Technology
Product number
B4864
Product name
Tebipenem
Packaging
50mg
Price
$594
Updated
2021/12/16
ChemScene
Product number
CS-3444
Product name
Tebipenem
Purity
>98.0%
Packaging
50mg
Price
$900
Updated
2021/12/16
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Tebipenem Chemical Properties,Usage,Production

Biological Activity

tebipenem is an orally available carbapenem antibiotic. tebipenem is active against a panel of clinical isolates from a variety of bacterial species (mic50s ≤ 0.0039 ~ 8 μg/ml), including methicillin-resistant strains of staphylococcus aureus (s. aureus) and staphylococcus epidermidis (s. epidermidis), as well as penicillin-resistant streptococcus pneumoniae (s. pneumonia). tebipenem also inhibits β-lactamase in a time- and concentration-dependent manner. tebipenem pivoxil, a derivative of tebipenem, has been under development as the first orally available carbapenem antibiotic for the treatment of respiratory and otolaryngological infections caused by drug-resistant s. pneumonia in pediatric patients.1. hazra s, xu h, blanchard js. tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from mycobacterium tuberculosis. biochemistry, 2014, 53(22): 3671-3678.2. fujimoto k, takemoto k, hatano k, et al. novel carbapenem antibiotics for parenteral and oral applications: in vitro and in vivo activities of 2-aryl carbapenems and their pharmacokinetics in laboratory animals. antimicrobial agents and chemotherapy, 2013, 57(2): 697-707.

Tebipenem Preparation Products And Raw materials

Raw materials

Preparation Products

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Tebipenem Suppliers

China 70 India 4 United States 9 Global 83
Beijing FaMu RuiSi Pharmaceuticals Co.,Ltd
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Bide Pharmatech Ltd.
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LETOPHARM LIMITED
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Energy Chemical
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MedBioPharmaceutical Technology Inc
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Wuhan Topule
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View Lastest Price from Tebipenem manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Tebipenem 161715-21-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Tebipenem 161715-21-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
Tebipenem 161715-21-5
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-20

161715-21-5, TebipenemRelated Search:

IBUTILIDE Lambrolizumab Cefpirome sulfate 2,2'-[Dithiobis(3,1-azetidinediyl)]bis[4,5-dihydrothiazole] RCIMVZWCHLOZJH-RRCSTGOVSA-N TEBIPENEM PIVOXIL

  • Tebipenem
  • (4R,5S,6S)-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • LJC 11036
  • LJC11036
  • LJC-11036
  • Tebipenem Impurity 5
  • (4R,5S,6S)-3-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
  • Tibipenem intermediate 2
  • (4R,5S,6S)-3-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicaci
  • Tebipenem USP/EP/BP
  • inhibit,LJC11036,Bacterial,LJC-11036,Antibiotic,Inhibitor
  • Tibipronam
  • 161715-21-5
  • API