Cefpirome sulfate

Product Name: Cefpirome sulfate
CAS No.: 98753-19-6
Chemical Name: Cefpirome sulfate
Synonyms: Cefquinome sulphate;Keiti;Broact;Cefrom;Keiten;Keitin);hr810sulfate;Cilastatinum;Cefquinome base;cefpiromeSodium
CBNumber: CB9262629
Molecular Formula: C22H24N6O9S3
Formula Weight: 612.66
MOL File: 98753-19-6.mol

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Cefpirome sulfate Property

Melting point:: 198-2020C (dec)
alpha: 25D -4.7° (c = 5 in H2O)
RTECS: UW8970000
storage temp.: Inert atmosphere,2-8°C
solubility: Soluble in DMSO
form: Solid
color: White to Off-White
λmax: 265nm(Buffer)(lit.)
Merck: 14,1940
InChIKey: RKTNPKZEPLCLSF-YBZTWAOJNA-N
SMILES: S(=O)(O)(O)=O.C(C1CS[C@@H]2[C@H](NC(=O)/C(=N\OC)/C3N=C(N)SC=3)C(=O)N2C=1C(=O)[O-])[N+]1C2CCCC=2C=CC=1 |&1:9,10,r|
CAS DataBase Reference: 98753-19-6(CAS DataBase Reference)

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Safety

HS Code: 2941.90.3000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A3862
Product name: Cefpirome sulfate
Packaging: 500 mg
Price: $362.5
Updated: 2025/07/31

TCI Chemical

Product number: C3007
Product name: Cefpirome Sulfate
Purity: >95.0%(HPLC)(N)
Packaging: 1g
Price: $81
Updated: 2025/07/31

TCI Chemical

Product number: C3007
Product name: Cefpirome Sulfate
Purity: >95.0%(HPLC)(N)
Packaging: 5g
Price: $280
Updated: 2025/07/31

Usbiological

Product number: 236814
Product name: Cefpirome Sulfate
Packaging: 250mg
Price: $207
Updated: 2021/12/16

TRC

Product number: C243500
Product name: Cefpirome Sulfate
Packaging: 2g
Price: $1100
Updated: 2021/12/16

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Cefpirome sulfate Chemical Properties,Usage,Production

Description

Cefpirome sulfate is a new injectable cephalosporin indicated for the treatment of severe urinary and respiratory tract infections, including septicemia and nosocomial infections. Cefpirome sulfate is reported to be the first true fourth-generation cephalosporin due to its similar activities to third-generation antibiotics against Gram-positive bacteria and to first-generation antibiotics against Gram-negative bacteria. Its efficacy against P.aeruginosa is comparable to ceftazidime. The broad spectrum of activity includes Klebsiella, methicillin-sensitive staphylococci, penicillin-resistant pneumococci, E.coli which generates extended-spectrum beta-lactamases and multi-resistant organisms such as Citrobacter, Enterobacter and Serratia.

Chemical Properties

White Crystalline Powder

Originator

Hoechst AG (Germany)

Uses

A fourth generation cephalosporin antibiotic

Definition

ChEBI: Cefpirome sulfate is an azaheterocycle sulfate salt. It is functionally related to a cefpirome.

brand name

Cefrom (Hoechst-Roussel).

Synthesis

533-37-9

80756-85-0

957-68-6

98753-19-6

The present invention employs a microwave-assisted synthesis method to synthesize cefpirome hydrogensulfate in the following steps: (1) 7-aminocephalosporanic acid (2.72 g, 0.01 mol, Compound I) was mixed homogeneously with (Z)-S-2-benzothiazolyl-2-amino-alpha-(methoxyimino)-4-thiazole thioacetate (AEMA, 3.85 g, 0.011 mol, Compound VII) was homogeneously mixed and ground, followed by the addition of 2,3-cyclopentenopyridine (2.3 g, 0.011 mol, Compound IV) and concentrated sulfuric acid (10.88 g, 98 wt%). (2) The microwave reaction was carried out sequentially: 300 W for 1 min, 450 W for 1 min and 750 W for 2 min. (3) After completion of the reaction, deionized water (29.92 g) was added to the residue, mixed and filtered, the filtrate was collected and the solvent was removed to obtain a white solid. The resulting solid was dried under vacuum at 50 °C for 4 h. Cefpirome hydrogen sulfate (5.09 g, yield 99.0%, purity ≥99.9%) was finally obtained.

References

[1] Patent: CN105646542, 2016, A. Location in patent: Paragraph 0027; 0040; 0041; 0042; 0043; 0044; 0045

Cefpirome sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefpirome sulfate Suppliers

Americas 1 Argentina 1 Bangladesh 1 Canada 2 China 305 Europe 4 Germany 3 India 22 Japan 1 Poland 2 South Korea 2 Spain 1 United Kingdom 8 United States 33 Global 386

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 400-880-2824; 13184580281
Fax: 400-880-2824
Email: hj@ruiweier.cn
Country: China
ProdList: 2686
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

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View Lastest Price from Cefpirome sulfate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Cefpirome sulfate 98753-19-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10mt
Release date: 2024-11-11

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Cefpirome Sulfate 98753-19-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-05-11

Shaanxi Dideu New Materials Co. Ltd

Product: Cefpirome sulfate 98753-19-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-15

98753-19-6, Cefpirome sulfateRelated Search:

Sodium sulfate Cefquinome sulfate calcium sulfate Sodium thiosulfate pentahydrate Acetylacetone Glycine Potassium sulfate N-Acetylsulfanilyl chloride Colistin sulfate Cefpirome Ferrous sulfate heptahydrate Betaine Acetaminophen Acetyl chloride Copper(II) sulfate Ferrous sulfate monohydrate Magnesium sulfate heptahydrate sulfate

1-[[(6r,7r)-7-[[(2z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5h-cyclopenta[b]pyridinium sulfate

CEFPIROME SULFATE

Keitin)

Cefquinome base

CefpiromeSulfate3%

1-(((6R,7R)-7-((Z)-2-(2-AMinothiazol-4-yl)-2-(MethoxyiMino)acetaMido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)Methyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-1-iuM hydrogensulfate

CEFPIROME SULFATE USP 27

(6r-rboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-

5h-1-pyrindinium,1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-ca

7-beta(z)))-(6-alphsulfate(1:1)

hr810sulfate

Cefquinome sulphate

CefpiromeSulfateC22H22N6O5S2H2So4

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5H-cyclopenta[b]pyrindinium Inner Salt

Broact

Cefrom

Keiti

Quinolinium, 1-(6R,7R)-7-(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetylamino-2-carboxy-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-en-3-ylmethyl-5,6,7,8-tetrahydro-, inner salt

5H-Cyclopenta[b]pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-, sulfate (1:1)

Keiten

cefpiromeSodium

Cefpirome Sulfate &gt

Cefpirome sulfate USP/EP/BP

CEFPIROME SULFATE(NON-STERILE)

Cefpirome sulfater

Cefpirome SulfateQ: What is Cefpirome Sulfate Q: What is the CAS Number of Cefpirome Sulfate Q: What is the storage condition of Cefpirome Sulfate Q: What are the applications of Cefpirome Sulfate

Cilastatin Monosodium Salt

Cilastatinum

Cefpirol sulfate (mixed sodium carbonate)

C11064500 CefpiromEsulfate

Cefpirome sulfate (with sodium carbonate)

98753-19-6

156-1-45

99-0-5

C22H24N6O9S3

C22H22N6O5S2H2O4S

C22H23N6O5S2H2SO4

C22H22N6O5S2H2SO4

C23H24N6O5S2

C22H24N6O9S3C22H22N6O5S2H2SO4

api

Pharmaceutical intermediate

Pharmaceutical raw material

Intermediates & Fine Chemicals

Pharmaceuticals

cephalosporins antibiotics

Antibacterial

Miscellaneous

98753-19-6