5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Product Name: 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS No.: 133627-17-5
Chemical Name: 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms: BIRH 414;BIRH 414 BS;Nevirapine EP Impurity A;Nevirapine Related CoMpound A;Nevirapine USP Related Compound A;11-Ethyl-4-methyl-5,11-dihydro-6H-d;Nevirapine Related Compound A (15 mg);Nevirapine EP Impurity A/ Nevirapine Related Compound A;11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
CBNumber: CB52539709
Molecular Formula: C14H14N4O
Formula Weight: 254.29
MOL File: 133627-17-5.mol

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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Property

Melting point:: 212-214℃ (1,2-dichloroethane )
Boiling point:: 389.8±42.0 °C(Predicted)
Density: 1.224±0.06 g/cm3(Predicted)
pka: 12.05±0.20(Predicted)

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Safety

HS Code: 2933997500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1460725
Product name: Nevirapine Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15MG
Price: $1300
Updated: 2024/03/01

Usbiological

Product number: 162856
Product name: BIRH 414
Packaging: 10mg
Price: $502
Updated: 2021/12/16

TRC

Product number: B399700
Product name: BIRH414
Packaging: 100mg
Price: $1510
Updated: 2021/12/16

AvaChem

Product number: 3831
Product name: Nevirapine Impurity A
Packaging: 5mg
Price: $175
Updated: 2021/12/16

AvaChem

Product number: 3831
Product name: Nevirapine Impurity A
Packaging: 10mg
Price: $275
Updated: 2021/12/16

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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemical Properties,Usage,Production

Uses

BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Suppliers

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133627-17-5, 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-oneRelated Search:

Nevirapine Related CoMpound A

Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one)

BIRH 414

11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one

Nevirapine EP Impurity A

BIRH 414 BS

Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one}

11-Ethyl-4-methyl-5,11-dihydro-6H-d

6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl-

Nevirapine Related Compound A (15 mg)

Nevirapine EP Impurity A/ Nevirapine Related Compound A

Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one

Nevirapine impurity Ⅱ {11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′ -e][1,4] diazepin-6-one}

Nevirapine USP Related Compound A

Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

11-Ethyl-4-methyl-5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

133627-17-5

25429

Pharmaceuticals, Intermediates & Fine Chemicals