ChemicalBook > CAS DataBase List > FMoc-N-Me-Cys(Trt)-OH

FMoc-N-Me-Cys(Trt)-OH

Product Name
FMoc-N-Me-Cys(Trt)-OH
CAS No.
944797-51-7
Chemical Name
FMoc-N-Me-Cys(Trt)-OH
Synonyms
FMoc-N-Me-Cys(Trt)-OH;Fmoc-N-Me-L-Cys(Trt)-OH;FMOC-N-ME-CYS(TRT)-OH 1 G;Fmoc-N-Me-Cys(Trt)-OH;FMOC-N-METHYL-L-CYSTEINE(TRT);Fmoc-N-methyl-L-cysteine(Trityl);(9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-Cys(Trt)-OH;(R)-2-[Fmoc(methyl)amino]-3-(tritylthio)propanoic Acid;N-α-(9-Fluorenylmethoxycarbonyl)-N-α-methyl-S-trityl-L-cysteine;N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-S-trityl-L-cysteine
CBNumber
CB52548053
Molecular Formula
C38H33NO4S
Formula Weight
599.74
MOL File
944797-51-7.mol
More
Less

FMoc-N-Me-Cys(Trt)-OH Property

Melting point:
234-239°C
Boiling point:
746.0±60.0 °C(Predicted)
Density 
1.260±0.06 g/cm3(Predicted)
storage temp. 
Store at -15°C to -25°C.
form 
Solid
pka
3.72±0.10(Predicted)
color 
White to off-white
optical activity
[α]22/D -25.0°, c = 0.5% in dichloromethane
InChIKey
RAKOPMQMPUNRGI-DHUJRADRSA-N
SMILES
C(O)(=O)[C@H](CSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C
More
Less

Safety

WGK Germany 
3
HS Code 
2930 90 16
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52348
Product name
Fmoc-N-Me-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
1g
Price
$795
Updated
2025/07/31
Sigma-Aldrich
Product number
773069
Product name
Fmoc-N-Me-Cys(Trt)-OH
Purity
97% (HPLC)
Packaging
1g
Price
$450.8
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52348
Product name
Fmoc-N-Me-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
250mg
Price
$245
Updated
2023/06/20
TCI Chemical
Product number
F1075
Product name
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-S-(triphenylmethyl)-L-cysteine
Packaging
100MG
Price
$166
Updated
2025/07/31
TRC
Product number
F657715
Product name
Fmoc-N-Me-L-Cys(Trt)-OH
Packaging
50mg
Price
$145
Updated
2021/12/16
More
Less

FMoc-N-Me-Cys(Trt)-OH Chemical Properties,Usage,Production

Uses

Fmoc-N-Me-L-Cys(Trt)-OH (CAS# 944797-51-7) is an fmoc- and trityl-protected derivative of L-cysteine (C995000) used as a building block for peptides or peptide fragments, such as the solid-phase synthesis of Triostin A.

Uses

Fmoc-N-Me-Cys(Trt)-OH is a Fmoc-protected derivative of N-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. The residue attached to the amino group of N-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. The introduction of this Fmoc-protected derivative is best achieved using HATU as a coupling reagent in the presence of DIPEA (N, N-Diisopropylethylamine).
It can also be used to prepare Fmoc-N-Me-Cys(Trt)-OAllyl intermediate for the solid-phase synthesis of dithiol Triostin A.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMoc-N-Me-Cys(Trt)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

FMoc-N-Me-Cys(Trt)-OH Suppliers

Americas 1 China 76 Europe 1 Germany 1 India 1 Japan 3 United States 7 Global 90
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75

944797-51-7, FMoc-N-Me-Cys(Trt)-OHRelated Search:

FMoc-N-Me-Asn(trt)-OH Fmoc-N-methyl-L-phenylalanine FMOC-SARCOSINE MONOHYDRATE Fmoc-N-methyl-L-glutamic acid 5-tert-butyl ester FMOC-N-ME-ARG(MTR)-OH Fmoc-N-Me-Lys(Boc)-OH (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid FMoc-N-Me-His(Trt)-OH Fmoc-N-methyl-L-isoleucine FMOC-N-Methyl-L-alanine Fmoc-N-Me-Arg(pbf)-OH FMoc-N-Me-D-Cys(Trt)-OH Boc-N-Me-Cys(Mob)-OH N-METHYL-DL-ASPARTIC ACID MONOHYDRATE (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-cyclohexylpropanoic acid N-Me-D-Asp(OtBu)-OMe·HCl N-Me-D-Asp(OtBu)-OH Z-N-Me-Asp(OtBu)-OH·DCHA

  • FMoc-N-Me-Cys(Trt)-OH
  • FMOC-N-METHYL-L-CYSTEINE(TRT)
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-S-(triphenylmethyl)-L-cysteine
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(tritylthio)propanoic acid
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-Cys(Trt)-OH
  • Fmoc-N-Me-L-Cys(Trt)-OH
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-[(triphenylmethyl)sulfanyl]propanoic acid
  • N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-S-trityl-L-cysteine
  • FMOC-N-ME-CYS(TRT)-OH 1 G
  • L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-S-(triphenylmethyl)-
  • Fmoc-N-methyl-L-cysteine(Trityl)
  • N-α-(9-Fluorenylmethoxycarbonyl)-N-α-methyl-S-trityl-L-cysteine
  • (2R)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-tritylsulfanylpropanoic acid
  • Fmoc-<i>N</i>-Me-Cys(Trt)-OH
  • (R)-2-[Fmoc(methyl)amino]-3-(tritylthio)propanoic Acid
  • 944797-51-7
  • amino acids