ChemicalBook > CAS DataBase List > 5,7-Dichloropyrido[4,3-b]pyrazine

5,7-Dichloropyrido[4,3-b]pyrazine

Product Name
5,7-Dichloropyrido[4,3-b]pyrazine
CAS No.
1379338-74-5
Chemical Name
5,7-Dichloropyrido[4,3-b]pyrazine
Synonyms
5,7-Dichloropyrido[4,3-b]pyrazine;Pyrido[3,4-b]pyrazine, 5,7-dichloro-;(5,7-dichloropyrido[3,4-b]pyrazine, 98%min
CBNumber
CB52550025
Molecular Formula
C7H3Cl2N3
Formula Weight
200.02
MOL File
1379338-74-5.mol
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5,7-Dichloropyrido[4,3-b]pyrazine Property

Boiling point:
350.8±37.0 °C(Predicted)
Density 
1.573±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-0.71±0.30(Predicted)
Appearance
yellow solid
InChI
InChI=1S/C7H3Cl2N3/c8-5-3-4-6(7(9)12-5)11-2-1-10-4/h1-3H
InChIKey
SNWNPXRUXXCDOM-UHFFFAOYSA-N
SMILES
C12=C(Cl)N=C(Cl)C=C1N=CC=N2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

H331Toxic if inhaled

H401Toxic to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P311Call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D439333
Product name
5,7-Dichloropyrido[3,4-b]pyrazine
Packaging
5g
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
124761
Product name
5,7-Dichloro-Pyrido[3,4-b]pyrazine
Purity
95+%
Packaging
1g
Price
$594
Updated
2021/12/16
Crysdot
Product number
CD11268730
Product name
5,7-Dichloropyrido[3,4-b]pyrazine
Purity
97%
Packaging
10g
Price
$700
Updated
2021/12/16
Ambeed
Product number
A125181
Product name
5,7-Dichloropyrido[3,4-b]pyrazine
Purity
97%
Packaging
10g
Price
$725
Updated
2021/12/16
Crysdot
Product number
CD11268730
Product name
5,7-Dichloropyrido[3,4-b]pyrazine
Purity
97%
Packaging
25g
Price
$1124
Updated
2021/12/16
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5,7-Dichloropyrido[4,3-b]pyrazine Chemical Properties,Usage,Production

Synthesis

101079-63-4

131543-46-9

1379338-74-5

2,6-Dichloro-3,4-pyridinediamine (7.85 g, 0.044 mol) and 40% aqueous glyoxal (26 g, 0.178 mol) were mixed in ethanol and the reaction was carried out at reflux overnight. After completion of the reaction, the mixture was cooled to room temperature, the precipitate was collected, washed with ethanol and dried under vacuum to give 5,7-dichloropyrido[3,4-b]pyrazine (7.32 g, 83% yield).

References

[1] Patent: WO2012/167733, 2012, A1. Location in patent: Page/Page column 35
[2] Patent: WO2012/167423, 2012, A1. Location in patent: Page/Page column 32
[3] Patent: US2014/121200, 2014, A1. Location in patent: Paragraph 0143; 0147
[4] Patent: WO2012/123312, 2012, A1. Location in patent: Page/Page column 63
[5] Patent: US2014/5188, 2014, A1. Location in patent: Paragraph 0562; 0563; 0564

5,7-Dichloropyrido[4,3-b]pyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7-Dichloropyrido[4,3-b]pyrazine Suppliers

Shanghai Amico Chemicals Co. LTD
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