FC 131

Product Name: FC 131
CAS No.: 606968-52-9
Chemical Name: FC 131
Synonyms: FC131,FC-131;cyclo(2Nal-Gly-D-Tyr-Arg-Arg);Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
CBNumber: CB52550797
Molecular Formula: C36H47N11O6
Formula Weight: 729.83
MOL File: 606968-52-9.mol

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FC 131 Property

Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
pka: 9.89±0.15(Predicted)
form: Powder
Water Solubility: Soluble to 2 mg/ml in water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 11960
Product name: FC 131
Purity: ≥95%
Packaging: 1mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 11960
Product name: FC 131
Purity: ≥95%
Packaging: 5mg
Price: $543
Updated: 2024/03/01

Cayman Chemical

Product number: 11960
Product name: FC 131
Purity: ≥95%
Packaging: 10mg
Price: $961
Updated: 2024/03/01

TRC

Product number: C991350
Product name: Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
Packaging: 2.5mg
Price: $900
Updated: 2021/12/16

ChemScene

Product number: CS-0027759
Product name: FC131
Packaging: 1mg
Price: $95
Updated: 2021/12/16

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FC 131 Chemical Properties,Usage,Production

Description

C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC₅₀ = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC₅₀ = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

Uses

Cyclo[3-?(2-?naphthalenyl)?-?L-?alanylglycyl-?D-?tyrosyl-?L-?arginyl-?L-?arginyl] is a CXCR4 antagonist with anti-HIV properties.

Definition

ChEBI: Cyclo[3-(2-naphthalenyl)-l-alanylglycyl-d-tyrosyl-l-arginyl-l-arginyl] is an oligopeptide.

FC 131 Preparation Products And Raw materials

Raw materials

Preparation Products

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FC 131 Suppliers

China 20 India 1 United Kingdom 1 United States 8 Global 30

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606968-52-9, FC 131Related Search:

Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]

FC131,FC-131

cyclo(2Nal-Gly-D-Tyr-Arg-Arg)

606968-52-9

C36H47N11O6

CXCR4 antagonist.