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FC 131

Product Name
FC 131
CAS No.
606968-52-9
Chemical Name
FC 131
Synonyms
FC131,FC-131;cyclo(2Nal-Gly-D-Tyr-Arg-Arg);Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
CBNumber
CB52550797
Molecular Formula
C36H47N11O6
Formula Weight
729.83
MOL File
606968-52-9.mol
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FC 131 Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
pka
9.89±0.15(Predicted)
form 
Powder
Water Solubility 
Soluble to 2 mg/ml in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
11960
Product name
FC 131
Purity
≥95%
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
11960
Product name
FC 131
Purity
≥95%
Packaging
5mg
Price
$543
Updated
2024/03/01
Cayman Chemical
Product number
11960
Product name
FC 131
Purity
≥95%
Packaging
10mg
Price
$961
Updated
2024/03/01
TRC
Product number
C991350
Product name
Cyclo[3-​(2-​naphthalenyl)​-​L-​alanylglycyl-​D-​tyrosyl-​L-​arginyl-​L-​arginyl]
Packaging
2.5mg
Price
$900
Updated
2021/12/16
ChemScene
Product number
CS-0027759
Product name
FC131
Packaging
1mg
Price
$95
Updated
2021/12/16
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FC 131 Chemical Properties,Usage,Production

Description

C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC50 = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC50 = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

Uses

Cyclo[3-?(2-?naphthalenyl)?-?L-?alanylglycyl-?D-?tyrosyl-?L-?arginyl-?L-?arginyl] is a CXCR4 antagonist with anti-HIV properties.

Definition

ChEBI: Cyclo[3-(2-naphthalenyl)-l-alanylglycyl-d-tyrosyl-l-arginyl-l-arginyl] is an oligopeptide.

FC 131 Preparation Products And Raw materials

Raw materials

Preparation Products

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FC 131 Suppliers

China 20 India 1 United Kingdom 1 United States 8 Global 30

606968-52-9, FC 131Related Search:


  • Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
  • FC131,FC-131
  • cyclo(2Nal-Gly-D-Tyr-Arg-Arg)
  • 606968-52-9
  • C36H47N11O6
  • CXCR4 antagonist.