ATN-224

Product Name: ATN-224
CAS No.: 649749-10-0
Chemical Name: ATN-224
Synonyms: ATN-224;WTX-101);ATN 224,ATN224;Choline tetrathiomolybdate;Bis(choline)tetrathioMolybdate;ATN-224 (Choline tetrathiomolybdate;CHOLINE TETRATHIOMOLYBDATE;WTX-101;WTX 101;WTX101;2-Hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate;bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide
CBNumber: CB52582927
Molecular Formula: C5H14MoNOS4-
Formula Weight: 328.36
MOL File: 649749-10-0.mol

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ATN-224 Property

storage temp.: Store at -20°C
solubility: DMSO:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:PBS (pH 7.2):0.5(Max Conc. mg/mL);1.16(Max Conc. mM)
form: A crystalline solid
color: Pink to red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3409
Product name: ATN-224
Purity: ≥95% (elemental analysis)
Packaging: 5MG
Price: $81
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML3409
Product name: ATN-224
Purity: ≥95% (elemental analysis)
Packaging: 25MG
Price: $327
Updated: 2024/03/01

Cayman Chemical

Product number: 23553
Product name: ATN-224
Purity: ≥95%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 23553
Product name: ATN-224
Purity: ≥95%
Packaging: 5mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 23553
Product name: ATN-224
Purity: ≥95%
Packaging: 10mg
Price: $365
Updated: 2024/03/01

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ATN-224 Chemical Properties,Usage,Production

Description

ATN-224 is a choline salt of tetrathiomolybdate and an inhibitor of superoxide dismutase 1 (SOD1; IC₅₀s = 2.91 and 3.51 μM in human and mouse blood cells, respectively, in vitro). ATN-224 reduces the viability of cultured oxidative stress-resistant WEHI7.2 murine thymic lymphoma cells (EC₅₀s = 5-6 nM) and human diffuse large B cell lymphoma cell lines (EC₅₀s = 9.73-105.61 nM) independently of Bcl-2 and Bcl-xL. In vivo, ATN-224 (0.7 mg/kg) chelates copper to stabilize an antitumor viral vector, enhancing its efficacy against lung metastases in mice. It also inhibits angiogenesis in a mouse model (IC₅₀s = 1.50-3 mg/kg via gavage).

ATN-224 Preparation Products And Raw materials

Raw materials

Preparation Products

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ATN-224 Suppliers

China 28 India 1 United Kingdom 1 United States 5 Global 35

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Lanzhou Angeli Biochemical Technology Co., Ltd.

Tel: 0931-8235634 13321316780
Fax: +86(931) 4873122
Email: 1455540579@qq.com
Country: China
ProdList: 958
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6037 18920794737
Email: sales@heowns.com
Country: China
ProdList: 22988
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30238
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

649749-10-0, ATN-224Related Search:

ATN-224

Bis(choline)tetrathioMolybdate

ATN-224 (Choline tetrathiomolybdate

WTX-101)

Choline tetrathiomolybdate

CHOLINE TETRATHIOMOLYBDATE;WTX-101;WTX 101;WTX101

bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide

2-Hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate

ATN 224,ATN224

649749-10-0

2C5H14NOMoS4

C10H32MoN2O2S4