ChemicalBook > CAS DataBase List > GW 627368X

GW 627368X

Product Name
GW 627368X
CAS No.
439288-66-1
Chemical Name
GW 627368X
Synonyms
CS-1654;GW 627368;GW 627368X;GW627368(GW627368X);GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X;inhibit,Inhibitor,Prostaglandin Receptor,GW627368,GW 627368,GW-627368;N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide;2-(4-(4,9-Diethoxy-1-oxo-1H-benzo[f]isoindol-2(3H)-yl)phenyl)-N-(phenylsulfonyl)acetamide;N-(benzenesulfonyl)-2-(4-{4,9-diethoxy-1-oxo-1H,2H,3H-benzo[f]isoindol-2-yl}phenyl)acetamide;4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide
CBNumber
CB52591190
Molecular Formula
C30H28N2O6S
Formula Weight
544.62
MOL File
439288-66-1.mol
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GW 627368X Property

Density 
1.327±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 100 mg/mL (183.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
5.25±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
1mg
Price
$59
Updated
2024/03/01
Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
5mg
Price
$253
Updated
2024/03/01
Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
10mg
Price
$448
Updated
2024/03/01
Cayman Chemical
Product number
10009162
Product name
GW 627368X
Purity
≥96%
Packaging
25mg
Price
$979
Updated
2024/03/01
Tocris
Product number
4668
Product name
GW627368
Purity
≥98%(HPLC)
Packaging
10
Price
$267
Updated
2021/12/16
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GW 627368X Chemical Properties,Usage,Production

Description

The effects of prostaglandin E2 (PGE2) are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for human EP4 and TP receptors with Ki values of 100 nM and 158 nM, respectively. Affinity for all other human prostanoid receptors is >5.0 μM. In human washed platelets, GW 627368X produced 100% inhibition of U-46619 (EC100)-induced aggregation at a concentration of 10 μM.

Uses

GW 627368 is a selective EP4 receptor competitive antagonist.

GW 627368X Preparation Products And Raw materials

Raw materials

Preparation Products

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GW 627368X Suppliers

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View Lastest Price from GW 627368X manufacturers

Career Henan Chemical Co
Product
GW 627368X 439288-66-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2020-01-13

439288-66-1, GW 627368XRelated Search:

GW 4064 GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide GW-6604 Carbamic acid, N-[(5S)-5-[[(2R,3S)-3-(formylhydroxyamino)-2-(2-methylpropyl)-1-oxohexyl]amino]-6-oxo-6-(2-thiazolylamino)hexyl]-, phenylmethyl ester GW 6471 GW806742X ONO-AE3-208 CJ 033466 CJ-21058 CJ-42794 L-161,982 Grapiprant

  • GW 627368X
  • GW 627368
  • 4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide
  • 2-[4-(4,9-Diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]-N-(phenylsulfonyl)acetamide
  • GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X
  • CS-1654
  • GW627368(GW627368X)
  • N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide
  • 2-(4-(4,9-Diethoxy-1-oxo-1H-benzo[f]isoindol-2(3H)-yl)phenyl)-N-(phenylsulfonyl)acetamide
  • Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-
  • inhibit,Inhibitor,Prostaglandin Receptor,GW627368,GW 627368,GW-627368
  • N-(benzenesulfonyl)-2-(4-{4,9-diethoxy-1-oxo-1H,2H,3H-benzo[f]isoindol-2-yl}phenyl)acetamide
  • 439288-66-1
  • Inhibitors