2-(tert-Butylamino)ethyl methacrylate Property

Melting point:

100～105℃/12 mm

Boiling point:

82 °C10 mm Hg(lit.)

Density 

0.914 g/mL at 25 °C(lit.)

vapor pressure 

6Pa at 20℃

refractive index 

n20/D 1.442(lit.)

Flash point:

160 °F

solubility 

Slightly soluble in water

form 

clear liquid

pka

8.99±0.10(Predicted)

color 

Colorless to Light yellow

Water Solubility 

18g/L at 25℃

InChIKey

BEWCNXNIQCLWHP-UHFFFAOYSA-N

LogP

2.12 at 20℃

CAS DataBase Reference

3775-90-4(CAS DataBase Reference)

EPA Substance Registry System

2-(tert-Butylamino)ethyl methacrylate (3775-90-4)

Safety

Hazard Codes 

Xi

Risk Statements 

36/38-43

Safety Statements 

26

RIDADR 

1760

WGK Germany 

1

RTECS 

OZ3500000

TSCA 

TSCA listed

HS Code 

2922.19.9690

HazardClass 

8

PackingGroup 

II

Hazardous Substances Data

3775-90-4(Hazardous Substances Data)

Toxicity

dog,LDLo,intravenous,76uL/kg (0.076mL/kg),Journal of Pharmaceutical Sciences. Vol. 63, Pg. 376, 1974.

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-(tert-Butylamino)ethyl methacrylate Chemical Properties,Usage,Production

Uses

Researchers reported the preparation of latex particles from 2-(tert-butylamino)ethyl methacrylate (TBAEMA) using aqueous emulsion polymerization. The preparation of PTBAEMA-functionalized polyolefin fibers via ATRP and an azide-functional initiator has been reported. Poly[2-(tert-butylamino)ethyl methacrylate](PTBAEMA) is a neutral polymer, which is inherently biocidal with potential application in antifouling paints and coatings. The major role of PTBAEMA is to displace Ca2+ and/or Mg2+ ions from the outer membrane of the bacteria, which is accordingly disorganized and finally disrupted. This pendent bulky secondary amine does not need quaternization for antibacterial properties[1-2].

References

[1] Bayramgil, Nursel Pekel. “Synthesis and characterization of new methacrylate-type hydrogels containing 2-tert-butylamino ethyl groups for sorption purposes.” Journal of Applied Polymer Science 109 2 (2008): 1205–1211.
[2] Abdullah M Alswieleh. “Surface modification of pH-responsive poly(2-(tert-butylamino)ethyl methacrylate) brushes grafted on mesoporous silica nanoparticles.” Designed Monomers and Polymers 22 1 (2019): 226–235.

Safety Profile

Poison by intraperitoneal route. See also ESTERS and AMINES. Combustible when exposed to heat or flame. To fight fire, use alcohol foam, water spray or mist, dry chemical. When heated to decomposition it emits toxic fumes of NOx.