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Miriplatin

Product Name
Miriplatin
CAS No.
141977-79-9
Chemical Name
Miriplatin
Synonyms
Mibo;Miripla;Miplatin;SM 11355;[(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...;Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
CBNumber
CB52612602
Molecular Formula
C34H66N2O4Pt
Formula Weight
762
MOL File
141977-79-9.mol
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Miriplatin Property

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF : < 1 mg/mL (insoluble)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2720
Product name
Miriplatin
Purity
>97.5% (Pt analysis)
Packaging
10MG
Price
$75.4
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2720
Product name
Miriplatin
Purity
>97.5% (Pt analysis)
Packaging
50MG
Price
$306
Updated
2024/03/01
ChemScene
Product number
CS-3921
Product name
Miriplatin
Purity
>98.0%
Packaging
100mg
Price
$220
Updated
2021/12/16
AK Scientific
Product number
3854AH
Product name
Miriplatin
Packaging
50mg
Price
$236
Updated
2021/12/16
ChemScene
Product number
CS-3921
Product name
Miriplatin
Purity
>98.0%
Packaging
10mg
Price
$70
Updated
2021/12/16
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Miriplatin Chemical Properties,Usage,Production

Uses

Miplatin is a platinum-based anticancer drug developed by Japan's Sumitomo Pharmaceutical Co., Ltd. It is used in the treatment of liver cancer, malignant lymphoma, non-small cell lung cancer, small cell lung cancer and superficial bladder cancer.

Biological Activity

Miriplatin (SM-11355) is a derivative of cisplatin containing myristate as a carrier ligand. It is a novel lipophilic platinum complex for the treatment of hepatocellular carcinoma.

in vitro

Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.

< b>

in vivo

Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces tumor growth rates the growth of tumor in rats bearing AH109A cells.

Miriplatin Preparation Products And Raw materials

Raw materials

Preparation Products

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Miriplatin Suppliers

China 134 United Kingdom 1 United States 5 Global 140
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View Lastest Price from Miriplatin manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
Miriplatin 141977-79-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
90.0% min
Supply Ability
100kgs/month
Release date
2023-06-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
Miriplatin 141977-79-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Miriplatin 141977-79-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

141977-79-9, MiriplatinRelated Search:

Exemestane VILAZODONE Tegafur Azelnidipine Tolvaptan

  • [(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum
  • Miripla
  • SM 11355
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis...
  • (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum
  • Mibo
  • Miriplatin,SM11355,inhibit,Inhibitor,SM 11355,DNA Alkylator/Crosslinker
  • Miplatin
  • 141977-79-9
  • C34H68N2O4Pt