ChemicalBook > CAS DataBase List > (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
Uses- Product Name
- (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
- CAS No.
- 1033805-28-5
- Chemical Name
- (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
- Synonyms
- LX-1033;EOS-61310;LP 778902;Telotristat;Telotrisalt;2H7]-Telotristat;Telotristat, LP778902;LP-778902/ Telotristat;LP778902;LP 778902;LP-778902;inhibit,Telotristat,LP778902,Inhibitor,Tryptophan Hydroxylase,LP 778902,LP-778902
- CBNumber
- CB52618578
- Molecular Formula
- C25H22ClF3N6O3
- Formula Weight
- 546.93
- MOL File
- 1033805-28-5.mol
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(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Property
- Boiling point:
- 731.1±70.0 °C(Predicted)
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- ≥27.35 mg/mL in DMSO with ultrasonic; insoluble in H2O; insoluble in EtOH
- form
- Powder
- pka
- 2.04±0.10(Predicted)
- color
- White to light yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 29424
- Product name
- Telotristat
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29424
- Product name
- Telotristat
- Packaging
- 10mg
- Price
- $129
- Updated
- 2024/03/01
TRC
- Product number
- T017090
- Product name
- Telotristat
- Packaging
- 2.5mg
- Price
- $165
- Updated
- 2021/12/16
TRC
- Product number
- T017090
- Product name
- Telotristat
- Packaging
- 25mg
- Price
- $1320
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611607
- Product name
- Telotristat
- Packaging
- 250mg
- Price
- $1356.6
- Updated
- 2021/12/16
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(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Chemical Properties,Usage,Production
Uses
Telotristat acts as a tryptophan hydroxylase (TPH) inhibitor.
Uses
Telotristat acts as a tryptophan hydroxylase (TPH) inhibitor.
Definition
ChEBI: Telotristat is a phenylalanine derivative.
Biological Activity
telotristat is the active metabolite of lx1606(telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (tph) inhibitor with potential antiserotonergic activity.
(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Preparation Products And Raw materials
Raw materials
Preparation Products
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(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Suppliers
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View Lastest Price from (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Telotristat 1033805-28-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Telotristat 1033805-28-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
Career Henan Chemical Co
- Product
- (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat 1033805-28-5
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- ask
- Release date
- 2018-12-23