Uses
ChemicalBook > CAS DataBase List > (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat

(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat

Uses
Product Name
(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
CAS No.
1033805-28-5
Chemical Name
(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
Synonyms
LX-1033;EOS-61310;LP 778902;Telotristat;Telotrisalt;2H7]-Telotristat;Telotristat, LP778902;LP-778902/ Telotristat;LP778902;LP 778902;LP-778902;inhibit,Telotristat,LP778902,Inhibitor,Tryptophan Hydroxylase,LP 778902,LP-778902
CBNumber
CB52618578
Molecular Formula
C25H22ClF3N6O3
Formula Weight
546.93
MOL File
1033805-28-5.mol
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(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Property

Boiling point:
731.1±70.0 °C(Predicted)
Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
≥27.35 mg/mL in DMSO with ultrasonic; insoluble in H2O; insoluble in EtOH
form 
Powder
pka
2.04±0.10(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29424
Product name
Telotristat
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
29424
Product name
Telotristat
Packaging
10mg
Price
$129
Updated
2024/03/01
TRC
Product number
T017090
Product name
Telotristat
Packaging
2.5mg
Price
$165
Updated
2021/12/16
TRC
Product number
T017090
Product name
Telotristat
Packaging
25mg
Price
$1320
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611607
Product name
Telotristat
Packaging
250mg
Price
$1356.6
Updated
2021/12/16
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(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Chemical Properties,Usage,Production

Uses

Telotristat acts as a tryptophan hydroxylase (TPH) inhibitor.

Uses

Telotristat acts as a tryptophan hydroxylase (TPH) inhibitor.

Definition

ChEBI: Telotristat is a phenylalanine derivative.

Biological Activity

telotristat is the active metabolite of lx1606(telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (tph) inhibitor with potential antiserotonergic activity.

(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
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sales@boylechem.com
Country
China
ProdList
2922
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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PSN Pharmaceutical Technology Co., Ltd.
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86-25-57062118
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86-25-57065896
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sales@jspsn.com
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China
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BOC Sciences
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1-631-485-4226; 16314854226
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info@bocsci.com
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United States
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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(86) 21-58955996
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China
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7552
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EnliPharma Technology Co., Ltd
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0551-66399836 18955197623
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sales@enlipharma.com
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China
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DONGSHENG CHIRAL PHARMA
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180000000
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3755454181@qq.com
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China
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420
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Taizhou Tongxin Bio-Tech Co., Ltd
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0523-18601685-898 18652728585
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sales@allyrise.com
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China
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2769
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Suzhou yacoo science co.,Ltd
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0512-87182056 18013166090
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0512-87182056
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lingling.qi@yacoo.com.cn
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China
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7295
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LETOPHARM LIMITED
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+86-21-5821 5861
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+86-21-5106 2861
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sales@letopharm.com
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China
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2384
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View Lastest Price from (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Telotristat 1033805-28-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Telotristat 1033805-28-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat 1033805-28-5
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
ask
Release date
2018-12-23

1033805-28-5, (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, TelotristatRelated Search:


  • (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat
  • Telotristat
  • (2S)-2-Amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid
  • LP 778902
  • LP-778902/ Telotristat
  • (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoicacid
  • Telotristat, LP778902
  • Telotrisalt
  • EOS-61310
  • 4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine
  • LX-1033
  • LP778902;LP 778902;LP-778902
  • L-Phenylalanine, 4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-
  • 2H7]-Telotristat
  • inhibit,Telotristat,LP778902,Inhibitor,Tryptophan Hydroxylase,LP 778902,LP-778902
  • 1033805-28-5
  • C25H22ClF3N6O3